PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_009142650.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
Family WRKY
Protein Properties Length: 285aa    MW: 32201.1 Da    PI: 5.1173
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_009142650.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY87.51.1e-27101161259
                     --SS-EEEEEEE--TT-SS-EEEEEE-ST...T---EEEEEE-SSSTTEEEEEEES--SS- CS
            WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsa...gCpvkkkversaedpkvveitYegeHnhe 59 
                     dDgy+WrKYGqKe++gs +pr+Y+rCt++   +C + k+v++s++dp+++e++Y g+H+++
  XP_009142650.1 101 DDGYCWRKYGQKEIHGSINPRGYFRCTHRftqNCLAVKQVQKSDRDPSIFEVKYVGSHTCN 161
                     8***************************9999***************************97 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.801.4E-2593162IPR003657WRKY domain
PROSITE profilePS5081121.13895163IPR003657WRKY domain
SuperFamilySSF1182901.09E-2398161IPR003657WRKY domain
SMARTSM007749.5E-35100162IPR003657WRKY domain
PfamPF031068.2E-23101160IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010200Biological Processresponse to chitin
GO:0048527Biological Processlateral root development
GO:0005730Cellular Componentnucleolus
GO:0000987Molecular Functioncore promoter proximal region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 285 aa     Download sequence    Send to blast
MVMEEKLVIN ELEQGRELAQ RLMSNLKDTS SIESSKNLIS EILSIYQNAI SMLDDKKVLK  60
RSREIDDKDS KNVIKKRQVF EKKTEKVSFF VGAGQEKGSI DDGYCWRKYG QKEIHGSINP  120
RGYFRCTHRF TQNCLAVKQV QKSDRDPSIF EVKYVGSHTC NNTTTSPKTP NFSISMFQQE  180
DIKPTKTEEA MMSLEDLEST KNIFRTFSFS NYEIENAGGG WKGNLFHEDQ LSPAATTSGS  240
GITSEVATAP ASVENSETAD SYFSSLDNII DFGPDWLLSC DVLNW
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6ir8_A2e-2199160768OsWRKY45
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in guard cells, hypocotyls, and in the vascular tissues of cotyledon and root (PubMed:24773321). Mostly expressed in roots, at lower levels in leaves and petioles, and, to a lower extent, in stems, flowers and siliques (PubMed:22325892). {ECO:0000269|PubMed:22325892, ECO:0000269|PubMed:24773321}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the regulation of osmotic stress responses and stomatal movement (PubMed:24773321). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Positive regulator of EDS1-dependent defense against E.amylovora (PubMed:22316300). Together with WRKY70 and WRKY53, promotes resistance to P.syringae, probably by enhancing salicylic acid (SA)- dependent genes. Contributes to the suppression of jasmonic acid (MeJA)-induced expression of PDF1.2 (PubMed:22325892). Together with WRKY54 and WRKY70, promotes brassinosteroid (BR)-regulated plant growth but prevent drought response by modulating gene expression (PubMed:28576847). {ECO:0000250, ECO:0000269|PubMed:22316300, ECO:0000269|PubMed:22325892, ECO:0000269|PubMed:24773321, ECO:0000269|PubMed:28576847}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00112ampDAPTransfer from AT2G46400Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_009142650.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by drought, salt and hydrogen peroxide treatments (PubMed:24773321). Induced by salicylic acid (SA) (PubMed:22268143, PubMed:22325892). Up-regulated by E.amylovora (PubMed:22316300). Triggered by P.syringae (PubMed:22325892). {ECO:0000269|PubMed:22268143, ECO:0000269|PubMed:22316300, ECO:0000269|PubMed:22325892, ECO:0000269|PubMed:24773321}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHM5852840.0HM585284.1 Brassica rapa subsp. chinensis WRKY46 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009142650.10.0PREDICTED: probable WRKY transcription factor 46
RefseqXP_013671531.10.0probable WRKY transcription factor 46
RefseqXP_013710134.10.0probable WRKY transcription factor 46
RefseqXP_013752002.10.0probable WRKY transcription factor 46
SwissprotQ9SKD91e-142WRK46_ARATH; Probable WRKY transcription factor 46
TrEMBLM4CK060.0M4CK06_BRARP; Uncharacterized protein
STRINGBra004540.1-P0.0(Brassica rapa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM48882352
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G46400.11e-144WRKY DNA-binding protein 46
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Sheikh AH, et al.
    Regulation of WRKY46 Transcription Factor Function by Mitogen-Activated Protein Kinases in Arabidopsis thaliana.
    Front Plant Sci, 2016. 7: p. 61
    [PMID:26870073]
  3. Yan JY, et al.
    A WRKY Transcription Factor Regulates Fe Translocation under Fe Deficiency.
    Plant Physiol., 2016. 171(3): p. 2017-27
    [PMID:27208259]
  4. Chen J, et al.
    Arabidopsis WRKY46, WRKY54, and WRKY70 Transcription Factors Are Involved in Brassinosteroid-Regulated Plant Growth and Drought Responses.
    Plant Cell, 2017. 29(6): p. 1425-1439
    [PMID:28576847]
  5. Ma J, et al.
    Overexpression of TaWRKY146 Increases Drought Tolerance through Inducing Stomatal Closure in Arabidopsis thaliana.
    Front Plant Sci, 2017. 8: p. 2036
    [PMID:29225611]