PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_009113093.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
Family WRKY
Protein Properties Length: 552aa    MW: 60454 Da    PI: 6.0773
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_009113093.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY97.68.2e-31318376259
                     --SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS
            WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 
                     +Dg++WrKYGqK+ kg+++pr+YYrCt+a gCpv+k+v+r+aed +++++tYeg+Hnh+
  XP_009113093.1 318 SDGCQWRKYGQKMAKGNPCPRAYYRCTMAtGCPVRKQVQRCAEDRSILITTYEGNHNHP 376
                     7***************************99****************************7 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.805.2E-34302378IPR003657WRKY domain
SuperFamilySSF1182903.53E-28310378IPR003657WRKY domain
PROSITE profilePS5081129.838312378IPR003657WRKY domain
SMARTSM007742.4E-37317377IPR003657WRKY domain
PfamPF031064.7E-27319376IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0010200Biological Processresponse to chitin
GO:0016036Biological Processcellular response to phosphate starvation
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0080169Biological Processcellular response to boron-containing substance deprivation
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 552 aa     Download sequence    Send to blast
MAGGWSGLTL DSSSLDLINP NRFKNNNHRR FLNPLTMSRM GDEDDQKTNM SIDGSEFRFP  60
VSLSGIRDRE DDDSSSGVGR ENDREVPGEV DFFSDKKSRV CQDEVDDAGL RVKKEEQDDR  120
TDVNTGLNLR TTVNARSDQS VIDNGESSEM EDKRANNELV KLQDELKKMT MENEKLRELL  180
TQVSNNYTSL HMHLVSLMQQ QQQQQNKALE AAGKHEETIV PRQFIDLGPS RASDEAEDLS  240
NSSSEDRTRS GGCSAVERRN NEVRDGKRLG REESPETESN KVQKVNNSSP PTFEQSTEAT  300
MRKARVSVRA RSEATMISDG CQWRKYGQKM AKGNPCPRAY YRCTMATGCP VRKQVQRCAE  360
DRSILITTYE GNHNHPLPPA AVAMASTTMA AANMLLSGSM SSHDGMMNPT NLLARAVLPC  420
STSMATISAS APFPTVTLDL THAPPLPNGS SPSTAAATNN HNSLMLRPQQ QMTNLPPNML  480
PHVIGQALYN QSKFSGLQFS SGSPSAAQSH AVADTISALT ADPNFTAALA SVISSMINGS  540
NHHDGEGNNK NQ
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ayd_A1e-22304380176WRKY transcription factor 1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Bra.8600.0root| seed
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Roots, leaves, shoots, flowers and siliques.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the control of processes related to senescence and pathogen defense (PubMed:12000796). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:12000796). Activates the transcription of the SIRK gene and represses its own expression and that of the WRKY42 genes (PubMed:12000796). Modulates phosphate homeostasis and Pi translocation by regulating PHO1 expression (PubMed:25733771). {ECO:0000269|PubMed:12000796, ECO:0000269|PubMed:25733771}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00209DAPTransfer from AT1G62300Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_009113093.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By salicylic acid, ethylene, jasmonic acid, pathogens, wounding and strongly during leaf senescence. {ECO:0000269|PubMed:11449049, ECO:0000269|PubMed:11722756}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKF4300290.0KF430029.1 Brassica rapa WRKY transcription factor 6 (WRKY6) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013713768.10.0WRKY transcription factor 6
SwissprotQ9C5190.0WRKY6_ARATH; WRKY transcription factor 6
TrEMBLM4EE460.0M4EE46_BRARP; Uncharacterized protein
STRINGBra027057.1-P0.0(Brassica rapa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM105728107
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G62300.10.0WRKY family protein
Publications ? help Back to Top
  1. Zhou F, et al.
    High humidity suppresses ssi4-mediated cell death and disease resistance upstream of MAP kinase activation, H2O2 production and defense gene expression.
    Plant J., 2004. 39(6): p. 920-32
    [PMID:15341634]
  2. Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P
    An extracellular subtilase switch for immune priming in Arabidopsis.
    PLoS Pathog., 2013. 9(6): p. e1003445
    [PMID:23818851]
  3. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  4. Singh V,Roy S,Singh D,Nandi AK
    Arabidopsis flowering locus D influences systemic-acquired-resistance- induced expression and histone modifications of WRKY genes.
    J. Biosci., 2014. 39(1): p. 119-26
    [PMID:24499796]
  5. Ali MA,Wieczorek K,Kreil DP,Bohlmann H
    The beet cyst nematode Heterodera schachtii modulates the expression of WRKY transcription factors in syncytia to favour its development in Arabidopsis roots.
    PLoS ONE, 2014. 9(7): p. e102360
    [PMID:25033038]
  6. Chai J,Liu J,Zhou J,Xing D
    Mitogen-activated protein kinase 6 regulates NPR1 gene expression and activation during leaf senescence induced by salicylic acid.
    J. Exp. Bot., 2014. 65(22): p. 6513-28
    [PMID:25210078]
  7. Vermeirssen V,De Clercq I,Van Parys T,Van Breusegem F,Van de Peer Y
    Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress.
    Plant Cell, 2014. 26(12): p. 4656-79
    [PMID:25549671]
  8. Xiao D, et al.
    SENESCENCE-SUPPRESSED PROTEIN PHOSPHATASE Directly Interacts with the Cytoplasmic Domain of SENESCENCE-ASSOCIATED RECEPTOR-LIKE KINASE and Negatively Regulates Leaf Senescence in Arabidopsis.
    Plant Physiol., 2015. 169(2): p. 1275-91
    [PMID:26304848]
  9. Bakshi M, et al.
    WRKY6 restricts Piriformospora indica-stimulated and phosphate-induced root development in Arabidopsis.
    BMC Plant Biol., 2015. 15: p. 305
    [PMID:26718529]
  10. Huang Y,Feng CZ,Ye Q,Wu WH,Chen YF
    Arabidopsis WRKY6 Transcription Factor Acts as a Positive Regulator of Abscisic Acid Signaling during Seed Germination and Early Seedling Development.
    PLoS Genet., 2016. 12(2): p. e1005833
    [PMID:26829043]
  11. Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P
    Correction: An Extracellular Subtilase Switch for Immune Priming in Arabidopsis.
    PLoS Pathog., 2016. 12(11): p. e1006003
    [PMID:27806116]
  12. Li H, et al.
    BZR1 Positively Regulates Freezing Tolerance via CBF-Dependent and CBF-Independent Pathways in Arabidopsis.
    Mol Plant, 2017. 10(4): p. 545-559
    [PMID:28089951]
  13. Stetter MG,Benz M,Ludewig U
    Increased root hair density by loss of WRKY6 in Arabidopsis thaliana.
    PeerJ, 2017. 5: p. e2891
    [PMID:28149680]
  14. Zhou X, et al.
    StMYB44 negatively regulates phosphate transport by suppressing expression of PHOSPHATE1 in potato.
    J. Exp. Bot., 2017. 68(5): p. 1265-1281
    [PMID:28338870]
  15. Bakshi M, et al.
    Piriformospora indica Reprograms Gene Expression in Arabidopsis Phosphate Metabolism Mutants But Does Not Compensate for Phosphate Limitation.
    Front Microbiol, 2017. 8: p. 1262
    [PMID:28747898]
  16. Zhang Y, et al.
    DELLA proteins negatively regulate dark-induced senescence and chlorophyll degradation in Arabidopsis through interaction with the transcription factor WRKY6.
    Plant Cell Rep., 2018. 37(7): p. 981-992
    [PMID:29574486]