PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID GSBRNA2T00069548001
Common NameGSBRNA2T00069548001
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
Family E2F/DP
Protein Properties Length: 290aa    MW: 32773.3 Da    PI: 8.0153
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
GSBRNA2T00069548001genomeGenoscopeView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP75.17.3e-2450132371
              E2F_TDP   3 eksLrlltqkflklleksee.givtlnevakeLvse.................dvknkrRRiYDilNVLealnliekkekneirwkg 71 
                          + +Lr+++ +   +++k e+ +i+t++eva+e++s+                 ++kn+rRR+YD+lNV++al++i++ +k+eirwkg
  GSBRNA2T00069548001  50 GGGLRQFSVM---VCQKLEAkKITTYKEVADEIISDfatikqnaekplndneyNEKNIRRRVYDALNVFMALDIIAR-DKKEIRWKG 132
                          6799999999...****9999********************************************************.*******98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0094041.6E-987285IPR015648Transcription factor DP
Gene3DG3DSA:1.10.10.104.5E-3645136IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.7E-2948132IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023197.1E-2051132IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.24E-1851133IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF1440745.75E-37139277No hitNo description
SMARTSM011381.7E-48139289IPR014889Transcription factor DP, C-terminal
CDDcd144586.05E-30139240IPR014889Transcription factor DP, C-terminal
PfamPF087813.0E-33140262IPR014889Transcription factor DP, C-terminal
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0007049Biological Processcell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 290 aa     Download sequence    Send to blast
MEMDLFVTPE KQRNHPPSVS LGKTPVRRKL IVDDDNEVVS EKKGQSRTSG GGLRQFSVMV  60
CQKLEAKKIT TYKEVADEII SDFATIKQNA EKPLNDNEYN EKNIRRRVYD ALNVFMALDI  120
IARDKKEIRW KGLPITCKKD VEEVKMDRNK IMNSVQKKAA FLKELREKVS SLESLMSRNK  180
EMVVKTEGPA EGFTLPFILL ETNPHAVVEI EISEDMQLVH LDFNNTPFSV HDDAYILKLM  240
QEHKQQQQHR VSSPSSTHQH SSAHSSSSSC IASGTSGPVC WNSGTNDTR*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_B3e-2642134390PROTEIN (TRANSCRIPTION FACTOR DP-2)
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Bna.140290.0seed
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Low expression at the G1/S transition and increases during the S phase. S/G2 transitions. {ECO:0000269|PubMed:11669580}.
UniprotTISSUE SPECIFICITY: Strongly expressed in the actively dividing tissues of the shoot apical meristem, young leaf primordia, the vascular tissues of the maturing leaf primordia and axillary buds. {ECO:0000269|PubMed:11889041}.
Functional Description ? help Back to Top
Source Description
UniProtInvolved in the regulation of the G1/S transition. Increases the DNA binding and the transactivation activities of E2F proteins after heterodimerization. The complex DPA/E2FA promotes cell division and acts as a regulator of the endocycle. Positively regulates the activity of S phase-specific genes. {ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapGSBRNA2T00069548001
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by the transcription factor ERF114. {ECO:0000269|PubMed:23616605}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAJ2945310.0AJ294531.1 Arabidopsis thaliana mRNA for DP-like protein (dpa gene).
GenBankAJ3190270.0AJ319027.1 Arabidopsis thaliana partial mRNA for E2F dimerisation partner protein (dp2a gene).
GenBankAK1171350.0AK117135.1 Arabidopsis thaliana At5g02470 mRNA for putative DP-2 transcription factor, complete cds, clone: RAFL16-67-D16.
GenBankBT0052860.0BT005286.1 Arabidopsis thaliana At5g02470 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009122777.10.0PREDICTED: transcription factor-like protein DPA
SwissprotQ9FNY30.0DPA_ARATH; Transcription factor-like protein DPA
TrEMBLA0A078HSW00.0A0A078HSW0_BRANA; BnaA10g27090D protein
STRINGBra009586.1-P0.0(Brassica rapa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM116412233
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G02470.31e-174Transcription factor DP
Publications ? help Back to Top
  1. Chalhoub B, et al.
    Plant genetics. Early allopolyploid evolution in the post-Neolithic Brassica napus oilseed genome.
    Science, 2014. 345(6199): p. 950-3
    [PMID:25146293]