PlantRegMap
Plant Transcription Factor Database
PlantTFDB
v5.0
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID GSBRNA2T00059301001
Common NameGSBRNA2T00059301001
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
Family bZIP
Protein Properties Length: 234aa    MW: 25769.6 Da    PI: 4.6118
Description bZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
GSBRNA2T00059301001genomeGenoscopeView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1bZIP_125.13.9e-08138168434
                          XCHHHCHHHHHHHHHHHHHHHHHHHHHHHHH CS
               bZIP_1   4 lkrerrkqkNReAArrsRqRKkaeieeLeek 34 
                           k+ rr+ +NR AA rsR+RKk+++  Le+k
  GSBRNA2T00059301001 138 AKKRRRRVRNRDAAVRSRERKKEYVTDLEKK 168
                          6999*************************87 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.20.5.1709.4E-8131168No hitNo description
PROSITE profilePS502179.14137168IPR004827Basic-leucine zipper domain
PfamPF077161.5E-4139168IPR004827Basic-leucine zipper domain
SuperFamilySSF579597.73E-7139169No hitNo description
PROSITE patternPS000360142157IPR004827Basic-leucine zipper domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 234 aa     Download sequence    Send to blast
MAEELGCVGF LGEDDDLFLD FDLSLFTETP IAGDFIRSSP DSANSWIGDI ESQLMNDEDN  60
QNCLELDQQS VSEFLADIFV DDPTADSVTG KVDDVPTQGS DDAGKEKAVE KKRNDSGSEN  120
LDEAKVESEI SGDDDAIAKK RRRRVRNRDA AVRSRERKKE YVTDLEKKRW WKCFHDDKAG  180
VCCALVGIPA VGFPALVSGR HHLPIPPSPP TKDLLPSSGS RRTRKAGSKR ARE*
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1138143KKRRRR
2139144KRRRRV
3139158KRRRRVRNRDAAVRSRERKK
4141158RRRVRNRDAAVRSRERKK
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Bna.85174e-39flower| leaf| seed
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in seedlings, rosette and cauline leaves, stems, buds, flowers, siliques, immature seeds, anthers and pollen grains. {ECO:0000269|PubMed:19017746}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Plays a role in plant immunity and abiotic stress responses. {ECO:0000269|PubMed:15781873, ECO:0000269|PubMed:18574595, ECO:0000269|PubMed:19017746, ECO:0000269|PubMed:21482766, ECO:0000269|PubMed:22359644}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapGSBRNA2T00059301001
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By tunicamycin, DTT and azetidine-2-carboxylate. Isoform 2 is induced by heat. {ECO:0000269|PubMed:15781873, ECO:0000269|PubMed:21482766}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009107646.11e-112PREDICTED: bZIP transcription factor 60
SwissprotQ9C7S03e-27BZP60_ARATH; bZIP transcription factor 60
TrEMBLA0A078HDK01e-168A0A078HDK0_BRANA; BnaA08g04620D protein
STRINGBra034925.1-P1e-168(Brassica rapa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM46342848
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G42990.14e-24basic region/leucine zipper motif 60
Publications ? help Back to Top
  1. Deng Y,Srivastava R,Howell SH
    Protein kinase and ribonuclease domains of IRE1 confer stress tolerance, vegetative growth, and reproductive development in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2013. 110(48): p. 19633-8
    [PMID:24145452]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Nagashima Y,Iwata Y,Ashida M,Mishiba K,Koizumi N
    Exogenous salicylic acid activates two signaling arms of the unfolded protein response in Arabidopsis.
    Plant Cell Physiol., 2014. 55(10): p. 1772-8
    [PMID:25138441]
  4. Chalhoub B, et al.
    Plant genetics. Early allopolyploid evolution in the post-Neolithic Brassica napus oilseed genome.
    Science, 2014. 345(6199): p. 950-3
    [PMID:25146293]
  5. Parra-Rojas J,Moreno AA,Mitina I,Orellana A
    The dynamic of the splicing of bZIP60 and the proteins encoded by the spliced and unspliced mRNAs reveals some unique features during the activation of UPR in Arabidopsis thaliana.
    PLoS ONE, 2015. 10(4): p. e0122936
    [PMID:25860807]
  6. Zhang L,Chen H,Brandizzi F,Verchot J,Wang A
    The UPR branch IRE1-bZIP60 in plants plays an essential role in viral infection and is complementary to the only UPR pathway in yeast.
    PLoS Genet., 2015. 11(4): p. e1005164
    [PMID:25875739]
  7. Walley J, et al.
    Plastid-produced interorgannellar stress signal MEcPP potentiates induction of the unfolded protein response in endoplasmic reticulum.
    Proc. Natl. Acad. Sci. U.S.A., 2015. 112(19): p. 6212-7
    [PMID:25922532]
  8. Ma ZX, et al.
    The THERMOSENSITIVE MALE STERILE 1 Interacts with the BiPs via DnaJ Domain and Stimulates Their ATPase Enzyme Activities in Arabidopsis.
    PLoS ONE, 2015. 10(7): p. e0132500
    [PMID:26186593]
  9. Sagor GH, et al.
    The polyamine spermine induces the unfolded protein response via the MAPK cascade in Arabidopsis.
    Front Plant Sci, 2015. 6: p. 687
    [PMID:26442007]
  10. Deng Y, et al.
    IRE1, a component of the unfolded protein response signaling pathway, protects pollen development in Arabidopsis from heat stress.
    Plant J., 2016. 88(2): p. 193-204
    [PMID:27304577]
  11. Gaguancela OA, et al.
    The IRE1/bZIP60 Pathway and Bax Inhibitor 1 Suppress Systemic Accumulation of Potyviruses and Potexviruses in Arabidopsis and Nicotiana benthamiana Plants.
    Mol. Plant Microbe Interact., 2016. 29(10): p. 750-766
    [PMID:27578623]
  12. Meng Z,Ruberti C,Gong Z,Brandizzi F
    CPR5 modulates salicylic acid and the unfolded protein response to manage tradeoffs between plant growth and stress responses.
    Plant J., 2017. 89(3): p. 486-501
    [PMID:27747970]
  13. Wang B,Du H,Zhang Z,Xu W,Deng X
    BhbZIP60 from Resurrection Plant Boea hygrometrica Is an mRNA Splicing-Activated Endoplasmic Reticulum Stress Regulator Involved in Drought Tolerance.
    Front Plant Sci, 2017. 8: p. 245
    [PMID:28286511]
  14. Li Q, et al.
    Unfolded protein response activation compensates endoplasmic reticulum-associated degradation deficiency in Arabidopsis.
    J Integr Plant Biol, 2017. 59(7): p. 506-521
    [PMID:28418178]
  15. Zhang SS, et al.
    Tissue-Specific Transcriptomics Reveals an Important Role of the Unfolded Protein Response in Maintaining Fertility upon Heat Stress in Arabidopsis.
    Plant Cell, 2017. 29(5): p. 1007-1023
    [PMID:28442596]
  16. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]
  17. Ruberti C,Lai Y,Brandizzi F
    Recovery from temporary endoplasmic reticulum stress in plants relies on the tissue-specific and largely independent roles of bZIP28 and bZIP60, as well as an antagonizing function of BAX-Inhibitor 1 upon the pro-adaptive signaling mediated by bZIP28.
    Plant J., 2018. 93(1): p. 155-165
    [PMID:29124827]
  18. Kim JS,Yamaguchi-Shinozaki K,Shinozaki K
    ER-Anchored Transcription Factors bZIP17 and bZIP28 Regulate Root Elongation.
    Plant Physiol., 2018. 176(3): p. 2221-2230
    [PMID:29367234]