PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Bradi3g45590.2.p
Common NameBRADI_3g45590
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Brachypodieae; Brachypodium
Family C2H2
Protein Properties Length: 318aa    MW: 35866.1 Da    PI: 7.4515
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Bradi3g45590.2.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H211.90.000684159523
                      TTTEEESSHHHHHHHHHHT CS
           zf-C2H2  5 dCgksFsrksnLkrHirtH 23
                       Cgk+F +   L++H  +H
  Bradi3g45590.2.p 41 GCGKTFVDAGALRKHAHVH 59
                      6**************9887 PP

2zf-C2H215.84e-056488123
                      EEET..TTTEEESSHHHHHHHHHHT CS
           zf-C2H2  1 ykCp..dCgksFsrksnLkrHirtH 23
                      y C+   Cgk F ++s LkrH   H
  Bradi3g45590.2.p 64 YICHydGCGKKFLDSSKLKRHFLIH 88
                      89*******************8877 PP

3zf-C2H218.46.1e-0695118223
                       EET..TTTEEESSHHHHHHHHHHT CS
           zf-C2H2   2 kCp..dCgksFsrksnLkrHirtH 23 
                        C+   Cgk Fs   nLk H++tH
  Bradi3g45590.2.p  95 FCTyeGCGKAFSLDFNLKAHMKTH 118
                       688889*****************9 PP

4zf-C2H2187.8e-06124149123
                       EEET..TTTEEESSHHHHHHHHHH.T CS
           zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                       ++Cp   Cg++F++ s L+ H rt H
  Bradi3g45590.2.p 124 HPCPypECGRRFTQESKLRAHFRTqH 149
                       689999*****************999 PP

5zf-C2H212.20.00055188213123
                       EEET..TTTEEESSHHHHHHHHHH.T CS
           zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                       y+Cp   C k + + + L+ H+++ H
  Bradi3g45590.2.p 188 YVCPydGCAKAYIHEYKLNLHLKKeH 213
                       99*********************999 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM00355253859IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.601.2E-93961IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576676.78E-64184No hitNo description
Gene3DG3DSA:3.30.160.606.5E-146284IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015713.8176493IPR007087Zinc finger, C2H2
SMARTSM003550.00246488IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002806688IPR007087Zinc finger, C2H2
SuperFamilySSF576675.93E-1475128No hitNo description
Gene3DG3DSA:3.30.160.603.4E-1985119IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015711.57294123IPR007087Zinc finger, C2H2
SMARTSM003550.002694118IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028096118IPR007087Zinc finger, C2H2
PROSITE profilePS5015711.697124153IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.604.4E-8124147IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0057124149IPR015880Zinc finger, C2H2-like
SuperFamilySSF576671.4E-6125148No hitNo description
PROSITE patternPS000280126149IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.601.1E-8180210IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576671.4E-6183210No hitNo description
PROSITE profilePS501578.58188218IPR007087Zinc finger, C2H2
SMARTSM003550.012188213IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280190213IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 318 aa     Download sequence    Send to blast
MQAAAPRLRH RWVKEWIPQD LVIAGGPCAL YKWVREDSYD GCGKTFVDAG ALRKHAHVHG  60
ERQYICHYDG CGKKFLDSSK LKRHFLIHTG EKNFFCTYEG CGKAFSLDFN LKAHMKTHFA  120
DNYHPCPYPE CGRRFTQESK LRAHFRTQHE KNPGMPAAMN RNALGDHPHN TVKPPPVTPP  180
VPSAERPYVC PYDGCAKAYI HEYKLNLHLK KEHPNHFSDA GAQAGPSRST ASKSSRRSRP  240
SATAKMPLPK IPKRGAEYTT PSPAINIAEE HQWPRKVLYD DDSEETEEEG DKPADMGWGR  300
IAASSDDDDD EETEDEE*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C5e-343914710117PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapBradi3g45590.2.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010235528.10.0zinc finger transcription factor YY1 isoform X2
SwissprotQ2V3L31e-88YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A0Q3QDF60.0A0A0Q3QDF6_BRADI; Uncharacterized protein
STRINGBRADI3G45590.10.0(Brachypodium distachyon)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.13e-86C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]