PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G65640.1
Common NamebHLH093, BHLH93, EN47, K21L13.16
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 351aa    MW: 39484.2 Da    PI: 4.5417
Description beta HLH protein 93
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G65640.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH38.42.2e-12180223654
                  HHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHH CS
          HLH   6 nerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksL 54 
                   ++ErrRR+r+N++++ Lr+++Pk +      K++  +iL  A++Y+k+L
  AT5G65640.1 180 LMAERRRRKRLNDRLSMLRSIVPKiS------KMDRTSILGDAIDYMKEL 223
                  589*********************66......****************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088815.643174223IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474592.62E-16177242IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000104.4E-10180223IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.6E-12180229IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.101.1E-16181241IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000834.21E-5181223No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0007275Biological Processmulticellular organism development
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 351 aa     Download sequence    Send to blast
MELSTQMNVF EELLVPTKQE TTDNNINNLS FNGGFDHHHH QFFPNGYNID YLCFNNEEED  60
ENTLLYPSSF MDLISQPPPL LLHQPPPLQP LSPPLSSSAT AGATFDYPFL EALQEIIDSS  120
SSSPPLILQN GQEENFNNPM SYPSPLMESD QSKSFSVGYC GGETNKKKSK KLEGQPSKNL  180
MAERRRRKRL NDRLSMLRSI VPKISKMDRT SILGDAIDYM KELLDKINKL QDEEQELGNS  240
NNSHHSKLFG DLKDLNANEP LVRNSPKFEI DRRDEDTRVD ICCSPKPGLL LSTVNTLETL  300
GLEIEQCVIS CFSDFSLQAS CSEGAEQRDF ITSEDIKQAL FRNAGYGGSC L
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1165187KKKSKKLEGQPSKNLMAERRRRK
2182189ERRRRKRL
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.288970.0floral meristem| flower| inflorescence| leaf
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO1865327830.0
Genevisible247151_at0.0
Expression AtlasAT5G65640-
AtGenExpressAT5G65640-
ATTED-IIAT5G65640-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Broadly expressed. {ECO:0000269|PubMed:17088607}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor. May be involved in the differentiation of stomatal guard cells. {ECO:0000269|PubMed:17088607}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G65640.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G65640
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0256650.0BT025665.1 Arabidopsis thaliana At5g65640 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_569014.10.0transcription factor bHLH93
SwissprotQ9LSL10.0BH093_ARATH; Transcription factor bHLH93
TrEMBLM4E6K00.0M4E6K0_BRARP; Uncharacterized protein
STRINGAT5G65640.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM20432878
Representative plantOGRP26361130
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Sorensen AM, et al.
    The Arabidopsis ABORTED MICROSPORES (AMS) gene encodes a MYC class transcription factor.
    Plant J., 2003. 33(2): p. 413-23
    [PMID:12535353]
  3. Chinnusamy V, et al.
    ICE1: a regulator of cold-induced transcriptome and freezing tolerance in Arabidopsis.
    Genes Dev., 2003. 17(8): p. 1043-54
    [PMID:12672693]
  4. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  5. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  6. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  7. Hoth S, et al.
    Monitoring genome-wide changes in gene expression in response to endogenous cytokinin reveals targets in Arabidopsis thaliana.
    FEBS Lett., 2003. 554(3): p. 373-80
    [PMID:14623097]
  8. Scheible WR, et al.
    Genome-wide reprogramming of primary and secondary metabolism, protein synthesis, cellular growth processes, and the regulatory infrastructure of Arabidopsis in response to nitrogen.
    Plant Physiol., 2004. 136(1): p. 2483-99
    [PMID:15375205]
  9. Nagata T,Yamada H,Du Z,Todoriki S,Kikuchi S
    Microarray analysis of genes that respond to gamma-irradiation in Arabidopsis.
    J. Agric. Food Chem., 2005. 53(4): p. 1022-30
    [PMID:15713015]
  10. Oono Y, et al.
    Monitoring expression profiles of Arabidopsis genes during cold acclimation and deacclimation using DNA microarrays.
    Funct. Integr. Genomics, 2006. 6(3): p. 212-34
    [PMID:16463051]
  11. Ohashi-Ito K,Bergmann DC
    Arabidopsis FAMA controls the final proliferation/differentiation switch during stomatal development.
    Plant Cell, 2006. 18(10): p. 2493-505
    [PMID:17088607]
  12. Kanaoka MM, et al.
    SCREAM/ICE1 and SCREAM2 specify three cell-state transitional steps leading to arabidopsis stomatal differentiation.
    Plant Cell, 2008. 20(7): p. 1775-85
    [PMID:18641265]
  13. Hanada K, et al.
    Functional compensation of primary and secondary metabolites by duplicate genes in Arabidopsis thaliana.
    Mol. Biol. Evol., 2011. 28(1): p. 377-82
    [PMID:20736450]