PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G65510.1
Common NameAIL7, K21L13.1, PLT7
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family AP2
Protein Properties Length: 498aa    MW: 55448.1 Da    PI: 6.5127
Description AINTEGUMENTA-like 7
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G65510.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP243.39e-14230289155
          AP2   1 sgykGVrwdkkrgrWvAeIrd.pse.ng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 
                  s y+GV++++++gr++A+++d  +   g  ++ ++++lg ++ ++ Aa+a++ a++k++g
  AT5G65510.1 230 SIYRGVTRHRWTGRYEAHLWDnSCRrEGqaRKgRQVYLGGYDKEDRAARAYDLAALKYWG 289
                  57*******************666664478446**********99*************98 PP

2AP249.97.8e-16332383155
          AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                  s y+GV++++++grW A+I  +     +k  +lg+f t+eeAa+a++ a+ k++g
  AT5G65510.1 332 SIYRGVTRHHQQGRWQARIGRVAG---NKDLYLGTFATEEEAAEAYDIAAIKFRG 383
                  57****************988532...5************************997 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541718.5E-17230299IPR016177DNA-binding domain
PfamPF008477.4E-11230289IPR001471AP2/ERF domain
CDDcd000181.68E-22230299No hitNo description
PROSITE profilePS5103218.993231297IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.102.0E-15231298IPR001471AP2/ERF domain
SMARTSM003802.1E-28231303IPR001471AP2/ERF domain
PRINTSPR003674.0E-6232243IPR001471AP2/ERF domain
CDDcd000181.66E-11332391No hitNo description
PfamPF008473.3E-10332383IPR001471AP2/ERF domain
SuperFamilySSF541718.5E-18332392IPR016177DNA-binding domain
Gene3DG3DSA:3.30.730.104.4E-18333391IPR001471AP2/ERF domain
PROSITE profilePS5103219.111333391IPR001471AP2/ERF domain
SMARTSM003806.3E-30333397IPR001471AP2/ERF domain
PRINTSPR003674.0E-6373393IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009873Biological Processethylene-activated signaling pathway
GO:0010492Biological Processmaintenance of shoot apical meristem identity
GO:0060772Biological Processleaf phyllotactic patterning
GO:0060774Biological Processauxin mediated signaling pathway involved in phyllotactic patterning
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000037anatomyshoot apex
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009046anatomyflower
PO:0020100anatomyhypocotyl
PO:0025022anatomycollective leaf structure
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007611developmental stagepetal differentiation and expansion stage
Sequence ? help Back to Top
Protein Sequence    Length: 498 aa     Download sequence    Send to blast
MAPPMTNCLT FSLSPMEMLK STDQSHFSSS YDDSSTPYLI DNFYAFKEEA EIEAAAASMA  60
DSTTLSTFFD HSQTQIPKLE DFLGDSFVRY SDNQTETQDS SSLTPFYDPR HRTVAEGVTG  120
FFSDHHQPDF KTINSGPEIF DDSTTSNIGG THLSSHVVES STTAKLGFNG DCTTTGGVLS  180
LGVNNTSDQP LSCNNGERGG NSNKKKTVSK KETSDDSKKK IVETLGQRTS IYRGVTRHRW  240
TGRYEAHLWD NSCRREGQAR KGRQVYLGGY DKEDRAARAY DLAALKYWGS TATTNFPVSS  300
YSKELEEMNH MTKQEFIASL RRKSSGFSRG ASIYRGVTRH HQQGRWQARI GRVAGNKDLY  360
LGTFATEEEA AEAYDIAAIK FRGINAVTNF EMNRYDIEAV MNSSLPVGGA AAKRHKLKLA  420
LESPSSSSSD HNLQQQQLLP SSSPSDQNPN SIPCGIPFEP SVLYYHQNFF QHYPLVSDST  480
IQAPMNQAEF FLWPNQSY
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO2402564820.0
Genevisible247196_at0.0
Expression AtlasAT5G65510-
AtGenExpressAT5G65510-
ATTED-IIAT5G65510-
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Confined to the central region of inflorescence ane floral meristems, progressively restricted to the innermost cells of the dome. Also detected in developing stamen locules and later in sporogonous cells within locules. In carpel primordia, found in placenta and in young ovule primordia. {ECO:0000269|PubMed:15988559}.
UniprotTISSUE SPECIFICITY: Expressed in roots, seedlings, inflorescence, and siliques. Also detected at low levels in leaves. {ECO:0000269|PubMed:15988559}.
Functional Description ? help Back to Top
Source Description
UniProtProbably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.
Function -- GeneRIF ? help Back to Top
  1. PLT proteins are key regulators of PIN1 activity in control of phyllotaxis. PLT3, PLT5, and PLT7 are essential for normal phyllotaxis. [PLT7]
    [PMID: 21700457]
  2. ANT, AIL6 and AIL7 are expressed in distinct domains within the vegetative shoot apical meristem. Triple mutant shoot apical meristems exhibit morphological and cell division defects.
    [PMID: 22380923]
  3. In A. thaliana, three transcriptional regulators implicated in phyllotaxis, PLETHORA3 (PLT3), PLT5, and PLT7, are expressed in incipient lateral root primordia where they are required for primordium development and lateral root emergence.[PLT7]
    [PMID: 23684976]
  4. AIL genes exhibit unequal genetic redundancy with roles for AIL5, AIL6, and AIL7 only revealed in the absence of ANT function. AIL5, AIL6, and AIL7 act in a dose dependent manners in ant and other mutant backgrounds.
    [PMID: 25956884]
  5. This study characterized the effects of three PLETHORA (PLT) transcription factors, PLT3, PLT5, and PLT7, during lateral root outgrowth.
    [PMID: 29078398]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00589DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G65510.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G65510
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY5608870.0AY560887.1 Arabidopsis thaliana putative AP2/EREBP transcription factor (At5g65510) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001318882.10.0AINTEGUMENTA-like 7
RefseqNP_201354.50.0AINTEGUMENTA-like 7
SwissprotQ6J9N80.0AIL7_ARATH; AP2-like ethylene-responsive transcription factor AIL7
TrEMBLA0A1P8BA690.0A0A1P8BA69_ARATH; AINTEGUMENTA-like 7
STRINGAT5G65510.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM33332765
Representative plantOGRP11217209
Publications ? help Back to Top
  1. Todd J,Post-Beittenmiller D,Jaworski JG
    KCS1 encodes a fatty acid elongase 3-ketoacyl-CoA synthase affecting wax biosynthesis in Arabidopsis thaliana.
    Plant J., 1999. 17(2): p. 119-30
    [PMID:10074711]
  2. Krizek BA,Prost V,Macias A
    AINTEGUMENTA promotes petal identity and acts as a negative regulator of AGAMOUS.
    Plant Cell, 2000. 12(8): p. 1357-66
    [PMID:10948255]
  3. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  4. Nole-Wilson S,Tranby TL,Krizek BA
    AINTEGUMENTA-like (AIL) genes are expressed in young tissues and may specify meristematic or division-competent states.
    Plant Mol. Biol., 2005. 57(5): p. 613-28
    [PMID:15988559]
  5. Kim S,Soltis PS,Wall K,Soltis DE
    Phylogeny and domain evolution in the APETALA2-like gene family.
    Mol. Biol. Evol., 2006. 23(1): p. 107-20
    [PMID:16151182]
  6. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  7. Nakano T,Suzuki K,Fujimura T,Shinshi H
    Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
    Plant Physiol., 2006. 140(2): p. 411-32
    [PMID:16407444]
  8. Che P,Lall S,Nettleton D,Howell SH
    Gene expression programs during shoot, root, and callus development in Arabidopsis tissue culture.
    Plant Physiol., 2006. 141(2): p. 620-37
    [PMID:16648215]
  9. Prasad K, et al.
    Arabidopsis PLETHORA transcription factors control phyllotaxis.
    Curr. Biol., 2011. 21(13): p. 1123-8
    [PMID:21700457]
  10. Mudunkothge JS,Krizek BA
    Three Arabidopsis AIL/PLT genes act in combination to regulate shoot apical meristem function.
    Plant J., 2012. 71(1): p. 108-21
    [PMID:22380923]
  11. Pinon V,Prasad K,Grigg SP,Sanchez-Perez GF,Scheres B
    Local auxin biosynthesis regulation by PLETHORA transcription factors controls phyllotaxis in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2013. 110(3): p. 1107-12
    [PMID:23277580]
  12. Hofhuis H, et al.
    Phyllotaxis and rhizotaxis in Arabidopsis are modified by three PLETHORA transcription factors.
    Curr. Biol., 2013. 23(11): p. 956-62
    [PMID:23684976]
  13. Krizek BA
    AINTEGUMENTA-LIKE genes have partly overlapping functions with AINTEGUMENTA but make distinct contributions to Arabidopsis thaliana flower development.
    J. Exp. Bot., 2015. 66(15): p. 4537-49
    [PMID:25956884]
  14. Santuari L, et al.
    The PLETHORA Gene Regulatory Network Guides Growth and Cell Differentiation in Arabidopsis Roots.
    Plant Cell, 2016. 28(12): p. 2937-2951
    [PMID:27920338]
  15. Du Y,Scheres B
    PLETHORA transcription factors orchestrate de novo organ patterning during Arabidopsis lateral root outgrowth.
    Proc. Natl. Acad. Sci. U.S.A., 2017. 114(44): p. 11709-11714
    [PMID:29078398]
  16. Elliott RC, et al.
    AINTEGUMENTA, an APETALA2-like gene of Arabidopsis with pleiotropic roles in ovule development and floral organ growth.
    Plant Cell, 1996. 8(2): p. 155-68
    [PMID:8742707]
  17. Okamuro JK,Caster B,Villarroel R,Van Montagu M,Jofuku KD
    The AP2 domain of APETALA2 defines a large new family of DNA binding proteins in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 1997. 94(13): p. 7076-81
    [PMID:9192694]