PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G62020.1
Common NameAT-HSFB2A, HSF22, HSF6, HSFB2A, MTG10.4
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family HSF
Protein Properties Length: 299aa    MW: 34050.8 Da    PI: 6.0656
Description heat shock transcription factor B2A
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G62020.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind115.82.6e-36241152102
                   HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS
  HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 
                   Fl+k+++++ed++++++isw+e+g+sf+v+++++fak++Lpk+Fkh+nf+SFvRQLn+YgFkkv  ++         weF+++ Fk+g+k+ll++i+
   AT5G62020.1  24 FLTKTFNLVEDSSIDDVISWNEDGSSFIVWNPTDFAKDLLPKHFKHNNFSSFVRQLNTYGFKKVVPDR---------WEFSNDFFKRGEKRLLREIQ 111
                   9*****************************************************************99.........******************** PP

                   XXXX CS
  HSF_DNA-bind  99 rkks 102
                   r+k 
   AT5G62020.1 112 RRKI 115
                   *985 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM004151.1E-5420113IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene3DG3DSA:1.10.10.102.2E-3721113IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467853.94E-3421113IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF004471.1E-3124113IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000565.4E-192447IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000565.4E-196274IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS0043406387IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000565.4E-197587IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010200Biological Processresponse to chitin
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000037anatomyshoot apex
PO:0000293anatomyguard cell
PO:0009005anatomyroot
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020100anatomyhypocotyl
PO:0025022anatomycollective leaf structure
PO:0025195anatomypollen tube cell
PO:0025281anatomypollen
PO:0001017developmental stageM germinated pollen stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 299 aa     Download sequence    Send to blast
MNSPPVDAMI TGESSSQRSI PTPFLTKTFN LVEDSSIDDV ISWNEDGSSF IVWNPTDFAK  60
DLLPKHFKHN NFSSFVRQLN TYGFKKVVPD RWEFSNDFFK RGEKRLLREI QRRKITTTHQ  120
TVVAPSSEQR NQTMVVSPSN SGEDNNNNQV MSSSPSSWYC HQTKTTGNGG LSVELLEENE  180
KLRSQNIQLN RELTQMKSIC DNIYSLMSNY VGSQPTDRSY SPGGSSSQPM EFLPAKRFSE  240
MEIEEEEEAS PRLFGVPIGL KRTRSEGVQV KTTAVVGENS DEETPWLRHY NRTNQRVCN
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5d5u_B4e-23611312129Heat shock factor protein 1
5d5v_B4e-23611312129Heat shock factor protein 1
5d5v_D4e-23611312129Heat shock factor protein 1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.59730.0leaf
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO425687010.0
Genevisible247509_at0.0
Expression AtlasAT5G62020-
AtGenExpressAT5G62020-
ATTED-IIAT5G62020-
Functional Description ? help Back to Top
Source Description
TAIRmember of Heat Stress Transcription Factor (Hsf) family
UniProtTranscriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).
Function -- GeneRIF ? help Back to Top
  1. Regulation of gene expression at the HSFB2a locus influences vegetative and gametophytic development in Arabidopsis.
    [PMID: 24874772]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00575DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G62020.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Upstream Regulators) ? help Back to Top
Source Upstream Regulator (A: Activate/R: Repress)
ATRM AT2G30250 (A)
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT5G44420(A)
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G62020
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0086580.0BT008658.1 Arabidopsis thaliana clone RAFL21-11-D17 (R51273) putative heat shock factor 6 (At5g62020) mRNA, complete cds.
GenBankBT0085420.0BT008542.1 Arabidopsis thaliana clone U51273 putative heat shock factor 6 (At5g62020) mRNA, complete cds.
GenBankAK2296900.0AK229690.1 Arabidopsis thaliana mRNA for heat shock factor 6, complete cds, clone: RAFL21-11-D17.
GenBankAJ2518670.0AJ251867.1 Arabidopsis thaliana mRNA for heat shock factor 6 (hsf6 gene).
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_201008.20.0heat stress transcription factor B-2a
SwissprotQ9SCW40.0HFB2A_ARATH; Heat stress transcription factor B-2a
TrEMBLC0SVV50.0C0SVV5_ARATH; Putative uncharacterized protein At5g62020 (Fragment)
STRINGAT5G62020.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM96528111
Representative plantOGRP9617233
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Nover L, et al.
    Arabidopsis and the heat stress transcription factor world: how many heat stress transcription factors do we need?
    Cell Stress Chaperones, 2001. 6(3): p. 177-89
    [PMID:11599559]
  3. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  4. Truman W,de Zabala MT,Grant M
    Type III effectors orchestrate a complex interplay between transcriptional networks to modify basal defence responses during pathogenesis and resistance.
    Plant J., 2006. 46(1): p. 14-33
    [PMID:16553893]
  5. Lee J, et al.
    Analysis of transcription factor HY5 genomic binding sites revealed its hierarchical role in light regulation of development.
    Plant Cell, 2007. 19(3): p. 731-49
    [PMID:17337630]
  6. Ma S,Bohnert HJ
    Integration of Arabidopsis thaliana stress-related transcript profiles, promoter structures, and cell-specific expression.
    Genome Biol., 2007. 8(4): p. R49
    [PMID:17408486]
  7. Libault M,Wan J,Czechowski T,Udvardi M,Stacey G
    Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-ligase genes responding to chitin, a plant-defense elicitor.
    Mol. Plant Microbe Interact., 2007. 20(8): p. 900-11
    [PMID:17722694]
  8. Guo J, et al.
    Genome-wide analysis of heat shock transcription factor families in rice and Arabidopsis.
    J Genet Genomics, 2008. 35(2): p. 105-18
    [PMID:18407058]
  9. Wang Y, et al.
    Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.
    Plant Physiol., 2008. 148(3): p. 1201-11
    [PMID:18775970]
  10. Li S,Fu Q,Huang W,Yu D
    Functional analysis of an Arabidopsis transcription factor WRKY25 in heat stress.
    Plant Cell Rep., 2009. 28(4): p. 683-93
    [PMID:19125253]
  11. Ikeda M,Ohme-Takagi M
    A novel group of transcriptional repressors in Arabidopsis.
    Plant Cell Physiol., 2009. 50(5): p. 970-5
    [PMID:19324928]
  12. Kanchiswamy CN, et al.
    Regulation of Arabidopsis defense responses against Spodoptera littoralis by CPK-mediated calcium signaling.
    BMC Plant Biol., 2010. 10: p. 97
    [PMID:20504319]
  13. Nishizawa-Yokoi A, et al.
    HsfA1d and HsfA1e involved in the transcriptional regulation of HsfA2 function as key regulators for the Hsf signaling network in response to environmental stress.
    Plant Cell Physiol., 2011. 52(5): p. 933-45
    [PMID:21471117]
  14. Zhu X,Thalor SK,Takahashi Y,Berberich T,Kusano T
    An inhibitory effect of the sequence-conserved upstream open-reading frame on the translation of the main open-reading frame of HsfB1 transcripts in Arabidopsis.
    Plant Cell Environ., 2012. 35(11): p. 2014-30
    [PMID:22571635]
  15. Wunderlich M,Gross-Hardt R,Sch
    Heat shock factor HSFB2a involved in gametophyte development of Arabidopsis thaliana and its expression is controlled by a heat-inducible long non-coding antisense RNA.
    Plant Mol. Biol., 2014. 85(6): p. 541-50
    [PMID:24874772]
  16. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]