PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G60120.1
Common NameMGO3.10, TOE2
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family AP2
Protein Properties Length: 485aa    MW: 53164.2 Da    PI: 7.2621
Description target of early activation tagged (EAT) 2
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G60120.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP253.27.4e-17159208155
          AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 
                  s+y+GV++++++grW+++I+d      + k+++lg f+ta  Aa+a+++a+ k++g
  AT5G60120.1 159 SQYRGVTFYRRTGRWESHIWD------CgKQVYLGGFDTAHAAARAYDRAAVKFRG 208
                  78*******************......55***********************9997 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF008471.2E-8159208IPR001471AP2/ERF domain
SuperFamilySSF541713.14E-15159216IPR016177DNA-binding domain
CDDcd000182.20E-11159215No hitNo description
SMARTSM003804.0E-30160222IPR001471AP2/ERF domain
PROSITE profilePS5103217.332160216IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.102.0E-16160215IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009873Biological Processethylene-activated signaling pathway
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005515Molecular Functionprotein binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 485 aa     Download sequence    Send to blast
MLDLNLDVDS TESTQNERDS ITVKGVSLNQ MDESVTSNSS VVNAEASSCI DGEDELCSTR  60
TVKFQFEILK GGGEEEEEDD DERSAVMMTK EFFPVAKGMN FMDSSAQSSR STVDISFQRG  120
KQGGDFIGSG SGGGDASRVM QPPSQPVKKS RRGPRSKSSQ YRGVTFYRRT GRWESHIWDC  180
GKQVYLGGFD TAHAAARAYD RAAVKFRGLE ADINFVIGDY EEDLKQMANL SKEEVVQVLR  240
RQSSGFSRNN SRYQGVALQK IGGWGAQMEQ LHGNMGCDKA AVQWKGREAA SLIEPHASRM  300
IPEAANVKLD LNLGISLSLG DGPKQKDRAL RLHHVPNNSV CGRNTMMENH MAAAACDTPF  360
NFLKRGSDHL NNRHALPSAF FSPMERTPEK GLMLRSHQSF PARTWQGHDQ SSGGTAVAAT  420
APPLFSNAAS SGFSLSATRP PSSTAIHHPS QPFVNLNQPG LYVIHPSDYI SQHQHNLMNR  480
PQPPP
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.291840.0flower| seed
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible247664_at0.0
Expression AtlasAT5G60120-
AtGenExpressAT5G60120-
ATTED-IIAT5G60120-
Functional Description ? help Back to Top
Source Description
UniProtProbably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Regulates negatively the transition to flowering time and confers flowering time delay. {ECO:0000250, ECO:0000269|PubMed:14555699}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00616PBM24477691Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G60120.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR172a-2/EAT. {ECO:0000269|PubMed:14555699}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- MicroRNA ? help Back to Top
Source Description
miRTarBaseRegulated by ath-miR172b
Interaction ? help Back to Top
Source Intact With
BioGRIDAT1G14920, AT1G24625, AT1G28360
IntActSearch Q9LVG2
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G60120
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0019160.0BT001916.1 Arabidopsis thaliana clone C105157 putative APETALA2 protein (At5g60120) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_200820.30.0AP2-like ethylene-responsive transcription factor TOE2
SwissprotQ9LVG20.0TOE2_ARATH; AP2-like ethylene-responsive transcription factor TOE2
TrEMBLF4JXG90.0F4JXG9_ARATH; AP2-like ethylene-responsive transcription factor TOE2
STRINGAT5G60120.20.0(Arabidopsis thaliana)
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Kasschau KD, et al.
    P1/HC-Pro, a viral suppressor of RNA silencing, interferes with Arabidopsis development and miRNA unction.
    Dev. Cell, 2003. 4(2): p. 205-17
    [PMID:12586064]
  3. Aukerman MJ,Sakai H
    Regulation of flowering time and floral organ identity by a MicroRNA and its APETALA2-like target genes.
    Plant Cell, 2003. 15(11): p. 2730-41
    [PMID:14555699]
  4. Schmid M, et al.
    Dissection of floral induction pathways using global expression analysis.
    Development, 2003. 130(24): p. 6001-12
    [PMID:14573523]
  5. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  6. Axtell MJ,Bartel DP
    Antiquity of microRNAs and their targets in land plants.
    Plant Cell, 2005. 17(6): p. 1658-73
    [PMID:15849273]
  7. Nole-Wilson S,Tranby TL,Krizek BA
    AINTEGUMENTA-like (AIL) genes are expressed in young tissues and may specify meristematic or division-competent states.
    Plant Mol. Biol., 2005. 57(5): p. 613-28
    [PMID:15988559]
  8. Kim S,Soltis PS,Wall K,Soltis DE
    Phylogeny and domain evolution in the APETALA2-like gene family.
    Mol. Biol. Evol., 2006. 23(1): p. 107-20
    [PMID:16151182]
  9. Nakano T,Suzuki K,Fujimura T,Shinshi H
    Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
    Plant Physiol., 2006. 140(2): p. 411-32
    [PMID:16407444]
  10. Zhang B,Pan X,Cannon CH,Cobb GP,Anderson TA
    Conservation and divergence of plant microRNA genes.
    Plant J., 2006. 46(2): p. 243-59
    [PMID:16623887]
  11. Heyl A, et al.
    The transcriptional repressor ARR1-SRDX suppresses pleiotropic cytokinin activities in Arabidopsis.
    Plant Physiol., 2008. 147(3): p. 1380-95
    [PMID:18502977]
  12. GlaziƄska P,Zienkiewicz A,Wojciechowski W,Kopcewicz J
    The putative miR172 target gene InAPETALA2-like is involved in the photoperiodic flower induction of Ipomoea nil.
    J. Plant Physiol., 2009. 166(16): p. 1801-13
    [PMID:19560230]
  13. Arabidopsis Interactome Mapping Consortium
    Evidence for network evolution in an Arabidopsis interactome map.
    Science, 2011. 333(6042): p. 601-7
    [PMID:21798944]
  14. Causier B,Ashworth M,Guo W,Davies B
    The TOPLESS interactome: a framework for gene repression in Arabidopsis.
    Plant Physiol., 2012. 158(1): p. 423-38
    [PMID:22065421]
  15. Efroni I, et al.
    Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses.
    Dev. Cell, 2013. 24(4): p. 438-45
    [PMID:23449474]
  16. Mar
    Large-scale identification of gibberellin-related transcription factors defines group VII ETHYLENE RESPONSE FACTORS as functional DELLA partners.
    Plant Physiol., 2014. 166(2): p. 1022-32
    [PMID:25118255]