PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G58010.1
Common NameBHLH82, EN96, F2C19.2, LRL3
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 297aa    MW: 31470.3 Da    PI: 6.0377
Description LJRHL1-like 3
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G58010.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH36.49.5e-12110155555
                  HHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
          HLH   5 hnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                  h+++Er RR+ri +++  L+el+P+       K +Ka++L + +eY++ Lq
  AT5G58010.1 110 HSIAERLRRERIAERMKSLQELVPNT-----NKTDKASMLDEIIEYVRFLQ 155
                  99***********************7.....5******************9 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000837.72E-13103159No hitNo description
SuperFamilySSF474597.59E-17103164IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088817.028105154IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.102.0E-16107164IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000104.6E-9110155IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003535.2E-13111160IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045944Biological Processpositive regulation of transcription from RNA polymerase II promoter
GO:0080147Biological Processroot hair cell development
GO:0005634Cellular Componentnucleus
GO:0001046Molecular Functioncore promoter sequence-specific DNA binding
GO:0001228Molecular Functiontranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000256anatomyroot hair cell
PO:0000262anatomytrichoblast
PO:0000282anatomytrichome
PO:0003015anatomyprimary root differentiation zone
Sequence ? help Back to Top
Protein Sequence    Length: 297 aa     Download sequence    Send to blast
MENGNGEGKG EFINQNNDFF LDSMSMLSSL PPCWDPSLPP PPPPPQSLFH ALAVDAPFPD  60
QFHHPQESGG PTMGSQEGLQ PQGTVSTTSA PVVRQKPRVR ARRGQATDPH SIAERLRRER  120
IAERMKSLQE LVPNTNKTDK ASMLDEIIEY VRFLQLQVKV LSMSRLGGAG SVGPRLNGLS  180
AEAGGRLNAL TAPCNGLNGN GNATGSSNES LRSTEQRVAK LMEEDMGSAM QYLQGKGLCL  240
MPISLATAIS SSTTHSRGSL FNPISSAVAA EDSNVTATAV AAPEASSTMD DVSASKA
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1114119RLRRER
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO795393230.0
Genevisible247895_at0.0
Expression AtlasAT5G58010-
AtGenExpressAT5G58010-
ATTED-IIAT5G58010-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in trichomes of the root maturation zone. Detected constitutively in flowers. {ECO:0000269|PubMed:12679534, ECO:0000269|PubMed:16581911}.
Functional Description ? help Back to Top
Source Description
TAIREncodes a basic helix-loop-helix (bHLH) protein that regulates root hair development. One of the three Arabidopsis homologs of the Lotus japonicus ROOTHAIRLESS1 (LjRHL1) gene: At2g24260 (AtLRL1), At4g30980 (AtLRL2), and At5g58010 (AtLRL3).
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G58010.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by heat treatment. {ECO:0000269|PubMed:12679534}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G58010
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF4886140.0AF488614.1 Arabidopsis thaliana clone bHLH082 putative bHLH transcription factor mRNA, partial sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_200609.10.0LJRHL1-like 3
SwissprotQ9LSQ30.0BH082_ARATH; Transcription factor bHLH82
TrEMBLA0A178UI770.0A0A178UI77_ARATH; LRL3
STRINGAT5G58010.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM115851733
Representative plantOGRP5816313
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  5. Lee JY, et al.
    Transcriptional and posttranscriptional regulation of transcription factor expression in Arabidopsis roots.
    Proc. Natl. Acad. Sci. U.S.A., 2006. 103(15): p. 6055-60
    [PMID:16581911]
  6. Karas B, et al.
    Conservation of lotus and Arabidopsis basic helix-loop-helix proteins reveals new players in root hair development.
    Plant Physiol., 2009. 151(3): p. 1175-85
    [PMID:19675148]
  7. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  8. Bruex A, et al.
    A gene regulatory network for root epidermis cell differentiation in Arabidopsis.
    PLoS Genet., 2012. 8(1): p. e1002446
    [PMID:22253603]
  9. Efroni I, et al.
    Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses.
    Dev. Cell, 2013. 24(4): p. 438-45
    [PMID:23449474]
  10. Tam TH,Catarino B,Dolan L
    Conserved regulatory mechanism controls the development of cells with rooting functions in land plants.
    Proc. Natl. Acad. Sci. U.S.A., 2015. 112(29): p. E3959-68
    [PMID:26150509]
  11. Zhang J, et al.
    Sperm cells are passive cargo of the pollen tube in plant fertilization.
    Nat Plants, 2017. 3: p. 17079
    [PMID:28585562]