PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G56780.1
Common NameATET2, ET2, MIK19.25
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family HRT-like
Protein Properties Length: 483aa    MW: 54589.2 Da    PI: 9.0529
Description effector of transcription2
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G56780.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HRT-like52.48.6e-17277307131
     HRT-like   1 iCGviledGsvCkrqPvkgRKRCeeHKGmRi 31 
                  +CGv+ledG +C r+PvkgRKRC eHKG+R+
  AT5G56780.1 277 VCGVLLEDGGCCIRSPVKGRKRCIEHKGQRV 307
                  7*****************************7 PP

2HRT-like51.41.8e-16337367131
     HRT-like   1 iCGviledGsvCkrqPvkgRKRCeeHKGmRi 31 
                  +CGvil d  +C++ Pv+gRKRCe HKGmRi
  AT5G56780.1 337 VCGVILPDMEPCNKRPVPGRKRCEDHKGMRI 367
                  7*****************************7 PP

3HRT-like29.21.6e-09406432228
     HRT-like   2 CGviledGsvCkrqPvkgRKRCeeHKG 28 
                  C +++++G +C+r+  kg KRC++HK 
  AT5G56780.1 406 CEATTKNGLPCTRSSPKGSKRCWQHKE 432
                  99************************7 PP

4HRT-like60.72.3e-19453482231
     HRT-like   2 CGviledGsvCkrqPvkgRKRCeeHKGmRi 31 
                  CGv+l++G +C+r+PvkgRKRCeeHKGmRi
  AT5G56780.1 453 CGVKLGNGLICERSPVKGRKRCEEHKGMRI 482
                  *****************************7 PP

Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:2000033Biological Processregulation of seed dormancy process
GO:0005634Cellular Componentnucleus
GO:0005737Cellular Componentcytoplasm
GO:0097100Molecular Functionsupercoiled DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000037anatomyshoot apex
PO:0000293anatomyguard cell
PO:0009009anatomyplant embryo
PO:0009046anatomyflower
PO:0020100anatomyhypocotyl
PO:0025195anatomypollen tube cell
PO:0025281anatomypollen
PO:0001016developmental stageL mature pollen stage
PO:0001017developmental stageM germinated pollen stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007611developmental stagepetal differentiation and expansion stage
Sequence ? help Back to Top
Protein Sequence    Length: 483 aa     Download sequence    Send to blast
MEFGDGVSFA VVPTVFKRED YKRTKHDTVF SKWQVLIGSN DWEDFKNGKD GVGRYRVQNL  60
PRKSCPGLYE LGVAVIGQEQ CRKLEPDIVL ASYLGQAESV RSRLQRYGRS GAHLRNVNNL  120
NDCETIESPV KAVTGGLFED IFSKGGSILY RWAPMGSKRE AEATEGMLLS TFDYAWNKGS  180
NGERRQLDLL KKLGDREFMS KRKSGISRML FPFLRNQVGI RIKGEKHVLK EERKLTCDVD  240
EEKSNNFLTS ILKLTRSRPQ PVSDRFDEVD GSCSDIVCGV LLEDGGCCIR SPVKGRKRCI  300
EHKGQRVCRV SPEKQTPPKS EIFTGQDHHN HKDSDVVCGV ILPDMEPCNK RPVPGRKRCE  360
DHKGMRINAF LFLLNQTDRE KTVKDEKPDP ESHTESIEEE ALTRFCEATT KNGLPCTRSS  420
PKGSKRCWQH KEKTSSDTSP VYFQPEAAKN VACGVKLGNG LICERSPVKG RKRCEEHKGM  480
RIT
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.293660.0leaf
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO1453593320.0
Genevisible247974_at0.0
Expression AtlasAT5G56780-
AtGenExpressAT5G56780-
ATTED-IIAT5G56780-
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: During embryogenesis, expressed in the embryo at the late torpedo/cotyledon stage, at the onset of maturation. Not expressed during early stages of seed development or in mature seeds. {ECO:0000269|PubMed:22226340}.
UniprotTISSUE SPECIFICITY: Expressed in vascular tissues of stems, hypocotyls, leaves and flowers. Expressed in the vascular bundles of xylem in shoot parenchyma cells. Expressed in the remnant cytoplasm of differentiated fiber cells and in protoxylem element of parenchymal cells. {ECO:0000269|PubMed:17991462}.
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional regulator involved in the regulation of cell differentiation in meristems. Probably regulates the expression of various KNAT genes involved in the maintenance of the cells in an undifferentiated, merismastic state. Plays a role in the regulation of gibberellin 20 oxidase and the gibberellin-regulated protein GASA4. Localizes in the nucleus during the cellular differentiation state and may act via a single strand cutting domain (PubMed:17991462). Transcriptional regulator required for the induction of dormancy during late seed development. Interacts genetically with FUS3 and may be component of the same regulatory pathway during embryogenesis. Binds both linear and supercoiled DNA without sequence preference (PubMed:22226340). {ECO:0000269|PubMed:17991462, ECO:0000269|PubMed:22226340}.
Function -- GeneRIF ? help Back to Top
  1. A mutation analysis showed that AtET2 (At5g56780) affects the expression of various KNAT genes involved in the maintenance of the undifferentiated state of cambial meristem cells and plays a role in the regulation of GA5 and the cell-cycle-related GASA4.
    [PMID: 17991462]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G56780.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Disruption Phenotype ? help Back to Top
Source Description
UniProtDISRUPTION PHENOTYPE: Reduced levels of lignin in leaves and stems (PubMed:17991462). Reduced seed germination rate (PubMed:22226340). {ECO:0000269|PubMed:17991462, ECO:0000269|PubMed:22226340}.
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G56780
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankCP0026880.0CP002688.1 Arabidopsis thaliana chromosome 5 sequence.
GenBankAB0133920.0AB013392.1 Arabidopsis thaliana genomic DNA, chromosome 5, P1 clone:MIK19.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_200489.20.0effector of transcription2
SwissprotF4K9330.0ET2_ARATH; Protein EFFECTOR OF TRANSCRIPTION 2
TrEMBLD7MM690.0D7MM69_ARALL; Putative uncharacterized protein
STRINGAT5G56780.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM29542763
Representative plantOGRP52481420
Publications ? help Back to Top
  1. Ellerstr
    Ectopic expression of EFFECTOR OF TRANSCRIPTION perturbs gibberellin-mediated plant developmental processes.
    Plant Mol. Biol., 2005. 59(4): p. 663-81
    [PMID:16244914]
  2. Culligan KM,Robertson CE,Foreman J,Doerner P,Britt AB
    ATR and ATM play both distinct and additive roles in response to ionizing radiation.
    Plant J., 2006. 48(6): p. 947-61
    [PMID:17227549]
  3. Ivanov R, et al.
    EFFECTOR OF TRANSCRIPTION2 is involved in xylem differentiation and includes a functional DNA single strand cutting domain.
    Dev. Biol., 2008. 313(1): p. 93-106
    [PMID:17991462]
  4. Wang Y, et al.
    Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.
    Plant Physiol., 2008. 148(3): p. 1201-11
    [PMID:18775970]
  5. Hanada K, et al.
    Functional compensation of primary and secondary metabolites by duplicate genes in Arabidopsis thaliana.
    Mol. Biol. Evol., 2011. 28(1): p. 377-82
    [PMID:20736450]
  6. Ivanov R,Tiedemann J,Czihal A,Baumlein H
    Transcriptional regulator AtET2 is required for the induction of dormancy during late seed development.
    J. Plant Physiol., 2012. 169(5): p. 501-8
    [PMID:22226340]