PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G50915.2
Common NameBHLH137, EN89, K3K7
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 286aa    MW: 31773.4 Da    PI: 6.4033
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G50915.2genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH27.65.3e-09146193455
                  HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
          HLH   4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                  +h+ +Er RR++i +++ +L+ l+P +    +k   Ka +L + ++Y++ Lq
  AT5G50915.2 146 SHSLAERVRREKISERMRTLQNLVPGC----DKVTGKALMLDEIINYVQTLQ 193
                  8*************************9....555****************99 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF474599.68E-17140207IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000839.93E-11140197No hitNo description
Gene3DG3DSA:4.10.280.101.8E-16142204IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088815.453142192IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.8E-6146193IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003533.0E-9148198IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009739Biological Processresponse to gibberellin
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000084anatomyplant sperm cell
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 286 aa     Download sequence    Send to blast
MATFSYFQNY PHSLLDPLLF PTPHSSINLT SFIDQNHLYP LPNISTVEDI SFLEYNVDKT  60
ENSGSEKLAN TTKTATTGSS SCDQLSHGPS AITNTGKTRG RKARNSNNSK EGVEGRKSKK  120
QKRGSKEEPP TDYIHVRARR GQATDSHSLA ERVRREKISE RMRTLQNLVP GCDKVTGKAL  180
MLDEIINYVQ TLQTQVEFLS MKLTSISPVV YDFGSDLDGL ILQSEMGSPE VGTSFTNAMP  240
TTTPIFPSLL DNSVVPTHAQ VQEEGEEREN FVDRSGFNNN NFCSFP
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.236010.0silique
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible248460_at0.0
Expression AtlasAT5G50915-
AtGenExpressAT5G50915-
ATTED-IIAT5G50915-
Function -- GeneRIF ? help Back to Top
  1. Data show that TTG1-bHLH-MYB complex directly regulating activators and repressors and the movement of repressors to affect trichome patterning on the Arabidopsis leaf.
    [PMID: 18434419]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G50915.2
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G50915
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY1130590.0AY113059.1 Arabidopsis thaliana At5g50917/At5g50917 mRNA, complete cds.
GenBankAY0876020.0AY087602.1 Arabidopsis thaliana clone 36971 mRNA, complete sequence.
GenBankAY0575490.0AY057549.1 Arabidopsis thaliana probable DNA-binding protein mRNA, complete cds.
GenBankAF4283500.0AF428350.1 Arabidopsis thaliana unknown protein mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_568745.10.0transcription factor bHLH137
RefseqNP_851163.10.0transcription factor bHLH137
SwissprotQ93W880.0BH137_ARATH; Transcription factor bHLH137
TrEMBLD7MQU81e-179D7MQU8_ARALL; Basic helix-loop-helix family protein
STRINGAT5G50915.10.0(Arabidopsis thaliana)
Publications ? help Back to Top
  1. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  2. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  3. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  4. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  5. Kiba T, et al.
    Combinatorial microarray analysis revealing arabidopsis genes implicated in cytokinin responses through the His->Asp Phosphorelay circuitry.
    Plant Cell Physiol., 2005. 46(2): p. 339-55
    [PMID:15695462]
  6. Hannah MA,Heyer AG,Hincha DK
    A global survey of gene regulation during cold acclimation in Arabidopsis thaliana.
    PLoS Genet., 2005. 1(2): p. e26
    [PMID:16121258]
  7. Cao D,Cheng H,Wu W,Soo HM,Peng J
    Gibberellin mobilizes distinct DELLA-dependent transcriptomes to regulate seed germination and floral development in Arabidopsis.
    Plant Physiol., 2006. 142(2): p. 509-25
    [PMID:16920880]
  8. Lee DJ, et al.
    Genome-wide expression profiling of ARABIDOPSIS RESPONSE REGULATOR 7(ARR7) overexpression in cytokinin response.
    Mol. Genet. Genomics, 2007. 277(2): p. 115-37
    [PMID:17061125]
  9. Bezhani S, et al.
    Unique, shared, and redundant roles for the Arabidopsis SWI/SNF chromatin remodeling ATPases BRAHMA and SPLAYED.
    Plant Cell, 2007. 19(2): p. 403-16
    [PMID:17293567]
  10. Johnston AJ, et al.
    Genetic subtraction profiling identifies genes essential for Arabidopsis reproduction and reveals interaction between the female gametophyte and the maternal sporophyte.
    Genome Biol., 2007. 8(10): p. R204
    [PMID:17915010]
  11. Zentella R, et al.
    Global analysis of della direct targets in early gibberellin signaling in Arabidopsis.
    Plant Cell, 2007. 19(10): p. 3037-57
    [PMID:17933900]
  12. Chan CW,Wohlbach DJ,Rodesch MJ,Sussman MR
    Transcriptional changes in response to growth of Arabidopsis in high external calcium.
    FEBS Lett., 2008. 582(6): p. 967-76
    [PMID:18307990]
  13. Zhao M,Morohashi K,Hatlestad G,Grotewold E,Lloyd A
    The TTG1-bHLH-MYB complex controls trichome cell fate and patterning through direct targeting of regulatory loci.
    Development, 2008. 135(11): p. 1991-9
    [PMID:18434419]
  14. Ascencio-Ib
    Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.
    Plant Physiol., 2008. 148(1): p. 436-54
    [PMID:18650403]
  15. Josse EM, et al.
    A DELLA in disguise: SPATULA restrains the growth of the developing Arabidopsis seedling.
    Plant Cell, 2011. 23(4): p. 1337-51
    [PMID:21478445]