PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G43170.1
Common NameAZF3, MMG4.21, ZF3
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family C2H2
Protein Properties Length: 193aa    MW: 21019.6 Da    PI: 8.865
Description zinc-finger protein 3
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G43170.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H213.40.000237597123
                 EEETTTTEEESSHHHHHHHHHHT CS
      zf-C2H2  1 ykCpdCgksFsrksnLkrHirtH 23
                 ykC+ C k+Fs+   L  H  +H
  AT5G43170.1 75 YKCGVCYKTFSSYQALGGHKASH 97
                 9***********99999998887 PP

2zf-C2H211.90.00071118137120
                  EEETTTTEEESSHHHHHHHH CS
      zf-C2H2   1 ykCpdCgksFsrksnLkrHi 20 
                  ++C+ CgksF +   L  H 
  AT5G43170.1 118 HVCSVCGKSFATGQALGGHK 137
                  79********9988776665 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576672.53E-1075140No hitNo description
PfamPF139123.9E-127599IPR007087Zinc finger, C2H2
PROSITE profilePS501579.397597IPR007087Zinc finger, C2H2
SMARTSM003550.197597IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002807797IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.1E-5116140IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.346118140IPR007087Zinc finger, C2H2
PfamPF139122.1E-12118142IPR007087Zinc finger, C2H2
SMARTSM003550.051118140IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280120140IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009409Biological Processresponse to cold
GO:0010200Biological Processresponse to chitin
GO:0042538Biological Processhyperosmotic salinity response
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005515Molecular Functionprotein binding
GO:0008270Molecular Functionzinc ion binding
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000084anatomyplant sperm cell
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001017developmental stageM germinated pollen stage
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 193 aa     Download sequence    Send to blast
MALEALNSPR LVEDPLRFNG VEQWTKCKKR SKRSRSDLHH NHRLTEEEYL AFCLMLLARD  60
GGDLDSVTVA EKPSYKCGVC YKTFSSYQAL GGHKASHRSL YGGGENDKST PSTAVKSHVC  120
SVCGKSFATG QALGGHKRCH YDGGVSNSEG VGSTSHVSSS SHRGFDLNII PVQGFSPDDE  180
VMSPMATKKP RLK
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO306942240.0
Genevisible249139_at0.0
Expression AtlasAT5G43170-
AtGenExpressAT5G43170-
ATTED-IIAT5G43170-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in roots. {ECO:0000269|PubMed:10806347, ECO:0000269|PubMed:15333755}.
Functional Description ? help Back to Top
Source Description
TAIREncodes zinc finger protein. mRNA levels are elevated in response to high salinity and low temperature. The protein is localized to the nucleus and acts as a transcriptional repressor.
UniProtTranscriptional repressor probably involved in abiotic stress responses. Binds DNA in a sequence-specific manner and can repress the transactivation activity of other transcription factors. {ECO:0000269|PubMed:15333755}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G43170.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By abscisic acid (ABA), ethylene, salt, cold and heat. {ECO:0000269|PubMed:10806347, ECO:0000269|PubMed:15333755, ECO:0000269|PubMed:21852415}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Interaction ? help Back to Top
Source Intact With
BioGRIDAT5G51190, AT1G77450
IntActSearch Q9SSW0
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G43170
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankCP0026880.0CP002688.1 Arabidopsis thaliana chromosome 5 sequence.
GenBankAB0082670.0AB008267.1 Arabidopsis thaliana genomic DNA, chromosome 5, P1 clone:MMG4.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_199131.11e-143zinc-finger protein 3
SwissprotQ9SSW01e-145AZF3_ARATH; Zinc finger protein AZF3
TrEMBLD7MQ001e-110D7MQ00_ARALL; Putative uncharacterized protein
STRINGAT5G43170.11e-143(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM12112898
Representative plantOGRP13115149
Publications ? help Back to Top
  1. Sakamoto H,Araki T,Meshi T,Iwabuchi M
    Expression of a subset of the Arabidopsis Cys(2)/His(2)-type zinc-finger protein gene family under water stress.
    Gene, 2000. 248(1-2): p. 23-32
    [PMID:10806347]
  2. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  3. Englbrecht CC,Schoof H,B
    Conservation, diversification and expansion of C2H2 zinc finger proteins in the Arabidopsis thaliana genome.
    BMC Genomics, 2004. 5(1): p. 39
    [PMID:15236668]
  4. Sakamoto H, et al.
    Arabidopsis Cys2/His2-type zinc-finger proteins function as transcription repressors under drought, cold, and high-salinity stress conditions.
    Plant Physiol., 2004. 136(1): p. 2734-46
    [PMID:15333755]
  5. Miao Y,Laun T,Zimmermann P,Zentgraf U
    Targets of the WRKY53 transcription factor and its role during leaf senescence in Arabidopsis.
    Plant Mol. Biol., 2004. 55(6): p. 853-67
    [PMID:15604721]
  6. Libault M,Wan J,Czechowski T,Udvardi M,Stacey G
    Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-ligase genes responding to chitin, a plant-defense elicitor.
    Mol. Plant Microbe Interact., 2007. 20(8): p. 900-11
    [PMID:17722694]
  7. Rossel JB, et al.
    Systemic and intracellular responses to photooxidative stress in Arabidopsis.
    Plant Cell, 2007. 19(12): p. 4091-110
    [PMID:18156220]
  8. Dortay H, et al.
    Toward an interaction map of the two-component signaling pathway of Arabidopsis thaliana.
    J. Proteome Res., 2008. 7(9): p. 3649-60
    [PMID:18642946]
  9. Kodaira KS, et al.
    Arabidopsis Cys2/His2 zinc-finger proteins AZF1 and AZF2 negatively regulate abscisic acid-repressive and auxin-inducible genes under abiotic stress conditions.
    Plant Physiol., 2011. 157(2): p. 742-56
    [PMID:21852415]
  10. Lumba S, et al.
    A mesoscale abscisic acid hormone interactome reveals a dynamic signaling landscape in Arabidopsis.
    Dev. Cell, 2014. 29(3): p. 360-72
    [PMID:24823379]