PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G42520.1
Common NameATBPC6, BBR/BPC6, BPC6, MDH9.22
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family BBR-BPC
Protein Properties Length: 342aa    MW: 38239.3 Da    PI: 9.6471
Description basic pentacysteine 6
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G42520.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1GAGA_bind4041.9e-12313421301
    GAGA_bind   1 mdddgsre..rnkgyyepaaslken.lglqlmssiaerdakirernlalsekkaavaerdmaflqrdkalaernkalverdnkllalllvensla... 92 
                  mdd g+re  r+k+  + +  ++++   +q+ms+iaerda+i+ernla+sekkaavaerdmaflqrd+a+aern+a++erd++l+al+++ens++   
  AT5G42520.1   1 MDDGGHREngRHKAAVQGQWLMQHQpSMKQVMSIIAERDAAIQERNLAISEKKAAVAERDMAFLQRDTAIAERNNAIMERDSALTALQYRENSMVtap 98 
                  99***9988999997775533333213359***************************************************************999** PP

    GAGA_bind  93 ....salpvgvqvlsgtksidslqqlse......pqledsavelreeeklealpieeaaeeakekkkkkkrqrakkpkekkakkkkkksekskkkvkk 180
                      sa+p+g+q+++g+k++++ +++++      pql+++a+e+re+e ++ lp++  a ++ e++k+k+++r  +pk++++++++k+++k+++kvkk
  AT5G42520.1  99 aanmSACPPGCQISRGVKHLHHPHMHHHhqqhhiPQLTENAYETREMEPNDGLPTSPPAGSTLESAKPKRGKR-VNPKATTQTAANKRGPKNQRKVKK 195
                  **999*****************99976679999************************************7766.5799******************** PP

    GAGA_bind 181 esad.er.......................skaekksidl.vlngvslDestlPvPvCsCtGalrqCYkWGnGGWqSaCCtttiSvyPLPvstkrrga 253
                  es+d  +                       sk+++ks+++ +ln+v +De+t+P+PvCsCtG+lrqCYkWGnGGWqS+CCttt+S+yPLP+ +++r+a
  AT5G42520.1 196 ESEDdLNkimfvktthdytdedsskhiligSKSDWKSQEMvGLNQVVYDETTMPPPVCSCTGVLRQCYKWGNGGWQSSCCTTTLSMYPLPALPNKRHA 293
                  **985448********************************88******************************************************** PP

    GAGA_bind 254 RiagrKmSqgafkklLekLaaeG.ydlsnpvDLkdhWAkHGtnkfvtir 301
                  R++grKmS++af+klL++LaaeG +dlsnpvDLkdhWAkHGtn+++ti+
  AT5G42520.1 294 RVGGRKMSGSAFNKLLSRLAAEGhHDLSNPVDLKDHWAKHGTNRYITIK 342
                  ***********************88***********************8 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF062171.7E-1021342IPR010409GAGA-binding transcriptional activator
SMARTSM012264.6E-1871342IPR010409GAGA-binding transcriptional activator
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009723Biological Processresponse to ethylene
GO:0005730Cellular Componentnucleolus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0042803Molecular Functionprotein homodimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 342 aa     Download sequence    Send to blast
MDDGGHRENG RHKAAVQGQW LMQHQPSMKQ VMSIIAERDA AIQERNLAIS EKKAAVAERD  60
MAFLQRDTAI AERNNAIMER DSALTALQYR ENSMVTAPAA NMSACPPGCQ ISRGVKHLHH  120
PHMHHHHQQH HIPQLTENAY ETREMEPNDG LPTSPPAGST LESAKPKRGK RVNPKATTQT  180
AANKRGPKNQ RKVKKESEDD LNKIMFVKTT HDYTDEDSSK HILIGSKSDW KSQEMVGLNQ  240
VVYDETTMPP PVCSCTGVLR QCYKWGNGGW QSSCCTTTLS MYPLPALPNK RHARVGGRKM  300
SGSAFNKLLS RLAAEGHHDL SNPVDLKDHW AKHGTNRYIT IK
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.301650.0cell culture| flower| leaf
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO1453587610.0
Genevisible249199_at0.0
Expression AtlasAT5G42520-
AtGenExpressAT5G42520-
ATTED-IIAT5G42520-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in seedlings, leaves and pistils. Detected in the base of flowers and tips of carpels, in sepal vasculature, in young rosette, in the lateral and tip of primary roots, and in ovule at the exception of the outer integument. {ECO:0000269|PubMed:14731261, ECO:0000269|PubMed:21435046}.
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional regulator that specifically binds to GA-rich elements (GAGA-repeats) present in regulatory sequences of genes involved in developmental processes. {ECO:0000269|PubMed:14731261}.
Function -- GeneRIF ? help Back to Top
  1. characterization of AtBPC6
    [PMID: 21347358]
  2. Arabidopsis (Arabidopsis thaliana) GAGA-motif binding factor protein basic pentacysteine6 (BPC6) interacts with like heterochromatin protein1 (LHP1), a PRC1 component, and associates with vernalization2 (VRN2), a PRC2 component, in vivo.
    [PMID: 26025051]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00540DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G42520.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Interaction ? help Back to Top
Source Intact With
BioGRIDAT5G42520
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G42520
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankEF1231080.0EF123108.1 Arabidopsis thaliana GAGA-binding transcriptional activator (BBR/BPC6) mRNA, complete cds.
GenBankBT0248740.0BT024874.1 Arabidopsis thaliana At5g42520 mRNA, complete cds.
GenBankAK2272460.0AK227246.1 Arabidopsis thaliana mRNA for hypothetical protein, complete cds, clone: RAFL11-01-O04.
GenBankAK2217520.0AK221752.1 Arabidopsis thaliana mRNA for hypothetical protein, complete cds, clone: RAFL21-54-A10.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_568605.10.0basic pentacysteine 6
SwissprotQ8L9990.0BPC6_ARATH; Protein BASIC PENTACYSTEINE6
TrEMBLR0GAL80.0R0GAL8_9BRAS; Uncharacterized protein
STRINGAT5G42520.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM61692647
Representative plantOGRP28411331
Publications ? help Back to Top
  1. Santi L, et al.
    The GA octodinucleotide repeat binding factor BBR participates in the transcriptional regulation of the homeobox gene Bkn3.
    Plant J., 2003. 34(6): p. 813-26
    [PMID:12795701]
  2. Meister RJ, et al.
    Definition and interactions of a positive regulatory element of the Arabidopsis INNER NO OUTER promoter.
    Plant J., 2004. 37(3): p. 426-38
    [PMID:14731261]
  3. Wanke D, et al.
    Alanine zipper-like coiled-coil domains are necessary for homotypic dimerization of plant GAGA-factors in the nucleus and nucleolus.
    PLoS ONE, 2011. 6(2): p. e16070
    [PMID:21347358]
  4. Monfared MM, et al.
    Overlapping and antagonistic activities of BASIC PENTACYSTEINE genes affect a range of developmental processes in Arabidopsis.
    Plant J., 2011. 66(6): p. 1020-31
    [PMID:21435046]
  5. Hecker A, et al.
    The Arabidopsis GAGA-Binding Factor BASIC PENTACYSTEINE6 Recruits the POLYCOMB-REPRESSIVE COMPLEX1 Component LIKE HETEROCHROMATIN PROTEIN1 to GAGA DNA Motifs.
    Plant Physiol., 2015. 168(3): p. 1013-24
    [PMID:26025051]