PlantTFDB
Plant Transcription Factor Database
v5.0
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G37800.1
Common NameATRSL1, BHLH86, EN113, K22F20.8, RSL1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 307aa    MW: 33325.7 Da    PI: 6.5159
Description RHD SIX-LIKE 1
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G37800.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH28.13.8e-09216257955
                  HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
          HLH   9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                   ++RR+ri +++  L+el+P+      +K++ +++LekA+ Y+k Lq
  AT5G37800.1 216 AKNRRERISERLKVLQELVPNG-----TKVDLVTMLEKAIGYVKFLQ 257
                  69******************97.....8******************9 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:4.10.280.105.9E-12207265IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088814.983207256IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474593.66E-13209267IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000839.54E-12209261No hitNo description
SMARTSM003533.8E-11213262IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000103.1E-6216257IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045944Biological Processpositive regulation of transcription from RNA polymerase II promoter
GO:0005634Cellular Componentnucleus
GO:0001046Molecular Functioncore promoter sequence-specific DNA binding
GO:0001228Molecular Functiontranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 307 aa     Download sequence    Send to blast
MSLINEHCNE RNYISTPNSS EDLSSPQNCG LDEGASASSS STINSDHQNN QGFVFYPSGE  60
TIEDHNSLMD FNASSFFTFD NHRSLISPVT NGGAFPVVDG NMSYSYDGWS HHQVDSISPR  120
VIKTPNSFET TSSFGLTSNS MSKPATNHGN GDWLYSGSTI VNIGSRHEST SPKLAGNKRP  180
FTGENTQLSK KPSSGTNGKI KPKATTSPKD PQSLAAKNRR ERISERLKVL QELVPNGTKV  240
DLVTMLEKAI GYVKFLQVQV KVLAADEFWP AQGGKAPDIS QVKEAIDAIL SSSQRDSNST  300
RETSIAE
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO184216880.0
Expression AtlasAT5G37800-
AtGenExpressAT5G37800-
Function -- GeneRIF ? help Back to Top
  1. data indicate that AtRHD6(At1g66470)and AtRSL1 (At5G37800) are bHLH transcription factors that are specifically required for the development of root hairs and act downstream of the genes that regulate epidermal pattern formation
    [PMID: 17556585]
  2. RSL1-PYL4 and RSL1-PYR1 interaction is localized to plasma membrane. RSL1 promoted PYL4 and PYR1 degradation in vivo and mediated in vitro ubiquitylation of the receptors.
    [PMID: 25330042]
  3. Expression of BdRSL class I genes in root hairless Arabidopsis thaliana root hair defective 6 (Atrhd6) Atrsl1 double mutants, devoid of RSL class I function, restores root hair development indicating that the function of these proteins has been conserved. However, neither AtRSL nor BdRSL class I genes is sufficient for root hair development in A. thaliana
    [PMID: 27494519]
  4. EIN3/EIL1 and RHD6/RSL1 coordinately enhance root hair initiation by selectively regulating a subset of core root hair genes.
    [PMID: 29233944]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G37800.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G37800
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0168730.0AB016873.1 Arabidopsis thaliana genomic DNA, chromosome 5, TAC clone:K22F20.
GenBankCP0026880.0CP002688.1 Arabidopsis thaliana chromosome 5 sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_198596.10.0RHD SIX-LIKE 1
SwissprotQ9FJ000.0BH086_ARATH; Putative transcription factor bHLH086
TrEMBLA0A178UPA10.0A0A178UPA1_ARATH; RSL1
STRINGAT5G37800.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM42602854
Representative plantOGRP35321326
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  5. Czechowski T,Bari RP,Stitt M,Scheible WR,Udvardi MK
    Real-time RT-PCR profiling of over 1400 Arabidopsis transcription factors: unprecedented sensitivity reveals novel root- and shoot-specific genes.
    Plant J., 2004. 38(2): p. 366-79
    [PMID:15078338]
  6. Osuna D, et al.
    Temporal responses of transcripts, enzyme activities and metabolites after adding sucrose to carbon-deprived Arabidopsis seedlings.
    Plant J., 2007. 49(3): p. 463-91
    [PMID:17217462]
  7. Menand B, et al.
    An ancient mechanism controls the development of cells with a rooting function in land plants.
    Science, 2007. 316(5830): p. 1477-80
    [PMID:17556585]
  8. Ohashi-Ito K,Bergmann DC
    Regulation of the Arabidopsis root vascular initial population by LONESOME HIGHWAY.
    Development, 2007. 134(16): p. 2959-68
    [PMID:17626058]
  9. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  10. Jang G,Yi K,Pires ND,Menand B,Dolan L
    RSL genes are sufficient for rhizoid system development in early diverging land plants.
    Development, 2011. 138(11): p. 2273-81
    [PMID:21558375]
  11. Efroni I, et al.
    Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses.
    Dev. Cell, 2013. 24(4): p. 438-45
    [PMID:23449474]
  12. Bueso E, et al.
    The single-subunit RING-type E3 ubiquitin ligase RSL1 targets PYL4 and PYR1 ABA receptors in plasma membrane to modulate abscisic acid signaling.
    Plant J., 2014. 80(6): p. 1057-71
    [PMID:25330042]
  13. Kim CM,Dolan L
    ROOT HAIR DEFECTIVE SIX-LIKE Class I Genes Promote Root Hair Development in the Grass Brachypodium distachyon.
    PLoS Genet., 2016. 12(8): p. e1006211
    [PMID:27494519]
  14. Feng Y, et al.
    Ethylene promotes root hair growth through coordinated EIN3/EIL1 and RHD6/RSL1 activity in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2017. 114(52): p. 13834-13839
    [PMID:29233944]