PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G29000.3
Common NameF3F24.100, PHL1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family G2-like
Protein Properties Length: 370aa    MW: 41423.1 Da    PI: 5.4353
Description G2-like family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G29000.3genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like104.75.4e-33188242155
      G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 
                  k+r+rWtpeLHe+Fveav+qLGGse+AtPk++l+l++ +gLt++hvkSHLQkYR+
  AT5G29000.3 188 KQRMRWTPELHEAFVEAVNQLGGSERATPKAVLKLLNNPGLTIYHVKSHLQKYRT 242
                  79****************************************************8 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129410.486185245IPR017930Myb domain
SuperFamilySSF466892.51E-17186242IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.602.3E-30186244IPR009057Homeodomain-like
TIGRFAMsTIGR015574.9E-23188242IPR006447Myb domain, plants
PfamPF002496.8E-11190241IPR001005SANT/Myb domain
PfamPF143795.1E-22276322IPR025756MYB-CC type transcription factor, LHEQLE-containing domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0020030anatomycotyledon
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001185developmental stageplant embryo globular stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 370 aa     Download sequence    Send to blast
MNNPVPCQSV SGGNSGGYLF PSSSGYCNVS AVLPHGRNLQ NQPPVSTVPR DRLAMQDCPL  60
IAQSSLINHH PQEFIDPLHE FFDFSDHVPV QNLQAESSGV RVDSSVELHK KSEWQDWADQ  120
LISVDDGSEP NWSELLGDSS SHNPNSEIPT PFLDVPRLDI TANQQQQMVS SEDQLSGRNS  180
SSSVATSKQR MRWTPELHEA FVEAVNQLGG SERATPKAVL KLLNNPGLTI YHVKSHLQKY  240
RTARYKPETS EVTGEPQEKK MTSIEDIKSL DMKTSVEITQ ALRLQMEVQK RLHEQLEIQR  300
SLQLQIEKQG RYLQMMFEKQ QKIQDNKSSS SEASPKQCNG SFAEVEVGLE TLTGDQNESA  360
SASRKRVRED
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6j4k_A7e-29188246260Protein PHOSPHATE STARVATION RESPONSE 1
6j4k_B7e-29188246260Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_A7e-29188246260Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_C7e-29188246260Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_D7e-29188246260Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_F7e-29188246260Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_H7e-29188246260Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_J7e-29188246260Protein PHOSPHATE STARVATION RESPONSE 1
Search in ModeBase
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO425681240.0
Genevisible246724_at0.0
Expression AtlasAT5G29000-
AtGenExpressAT5G29000-
ATTED-IIAT5G29000-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in shoots and roots. {ECO:0000269|PubMed:20838596}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor acting as central integrator of phosphate starvation responses (PubMed:20838596). Regulates FER1 expression upon phosphate starvation, linking iron and phosphate homeostasis (PubMed:23788639). {ECO:0000269|PubMed:20838596, ECO:0000269|PubMed:23788639}.
Function -- GeneRIF ? help Back to Top
  1. PHR1 and PHL1 are partially redundant transcription factors acting as central integrators of phosphate starvation responses.[PHL1]
    [PMID: 20838596]
  2. The results reveal a previously unknown link between Pro metabolism and phosphate nutrition and show that Pro biosynthesis is target of cross talk between Abscisic Acid (ABA) signaling and regulation of phosphate homeostasis through PHR1- and PHL1-mediated transcriptional activation of the P5CS1 gene.
    [PMID: 28765275]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00532DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G29000.3
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Not up-regulated by Pi starvation. {ECO:0000269|PubMed:26586833}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Interaction ? help Back to Top
Source Intact With
BioGRIDAT1G14920
Phenotype -- Disruption Phenotype ? help Back to Top
Source Description
UniProtDISRUPTION PHENOTYPE: No effect on phosphate starvation responsiveness, due to the redundancy with PHR1. {ECO:0000269|PubMed:20838596}.
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G29000
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY0459430.0AY045943.1 Arabidopsis thaliana unknown protein (At5g29000) mRNA, partial cds.
GenBankAY0851540.0AY085154.1 Arabidopsis thaliana clone 13378 mRNA, complete sequence.
GenBankBT0023440.0BT002344.1 Arabidopsis thaliana clone C104936 unknown protein (At5g29000) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001078629.10.0Homeodomain-like superfamily protein
RefseqNP_568512.30.0Homeodomain-like superfamily protein
RefseqNP_851090.10.0Homeodomain-like superfamily protein
SwissprotQ8GUN50.0PHL1_ARATH; Protein PHR1-LIKE 1
TrEMBLA0A178ULC50.0A0A178ULC5_ARATH; PHL1
TrEMBLA0A178ULG00.0A0A178ULG0_ARATH; PHL1
TrEMBLQ94AL70.0Q94AL7_ARATH; Uncharacterized protein At5g29000 (Fragment)
STRINGAT5G29000.20.0(Arabidopsis thaliana)
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Rubio V, et al.
    A conserved MYB transcription factor involved in phosphate starvation signaling both in vascular plants and in unicellular algae.
    Genes Dev., 2001. 15(16): p. 2122-33
    [PMID:11511543]
  3. Rizhsky L, et al.
    When defense pathways collide. The response of Arabidopsis to a combination of drought and heat stress.
    Plant Physiol., 2004. 134(4): p. 1683-96
    [PMID:15047901]
  4. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  5. Truman W,de Zabala MT,Grant M
    Type III effectors orchestrate a complex interplay between transcriptional networks to modify basal defence responses during pathogenesis and resistance.
    Plant J., 2006. 46(1): p. 14-33
    [PMID:16553893]
  6. Ascencio-Ib
    Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.
    Plant Physiol., 2008. 148(1): p. 436-54
    [PMID:18650403]
  7. Bustos R, et al.
    A central regulatory system largely controls transcriptional activation and repression responses to phosphate starvation in Arabidopsis.
    PLoS Genet., 2010. 6(9): p. e1001102
    [PMID:20838596]
  8. Ou B, et al.
    A high-throughput screening system for Arabidopsis transcription factors and its application to Med25-dependent transcriptional regulation.
    Mol Plant, 2011. 4(3): p. 546-55
    [PMID:21343311]
  9. Elfving N, et al.
    The Arabidopsis thaliana Med25 mediator subunit integrates environmental cues to control plant development.
    Proc. Natl. Acad. Sci. U.S.A., 2011. 108(20): p. 8245-50
    [PMID:21536906]
  10. Klopffleisch K, et al.
    Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis.
    Mol. Syst. Biol., 2011. 7: p. 532
    [PMID:21952135]
  11. Efroni I, et al.
    Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses.
    Dev. Cell, 2013. 24(4): p. 438-45
    [PMID:23449474]
  12. Kim DY,Scalf M,Smith LM,Vierstra RD
    Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis.
    Plant Cell, 2013. 25(5): p. 1523-40
    [PMID:23667124]
  13. Bournier M, et al.
    Arabidopsis ferritin 1 (AtFer1) gene regulation by the phosphate starvation response 1 (AtPHR1) transcription factor reveals a direct molecular link between iron and phosphate homeostasis.
    J. Biol. Chem., 2013. 288(31): p. 22670-80
    [PMID:23788639]
  14. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  15. Mar
    Large-scale identification of gibberellin-related transcription factors defines group VII ETHYLENE RESPONSE FACTORS as functional DELLA partners.
    Plant Physiol., 2014. 166(2): p. 1022-32
    [PMID:25118255]
  16. Bonnot C, et al.
    A chemical genetic strategy identify the PHOSTIN, a synthetic molecule that triggers phosphate starvation responses in Arabidopsis thaliana.
    New Phytol., 2016. 209(1): p. 161-76
    [PMID:26243630]
  17. Sun L,Song L,Zhang Y,Zheng Z,Liu D
    Arabidopsis PHL2 and PHR1 Act Redundantly as the Key Components of the Central Regulatory System Controlling Transcriptional Responses to Phosphate Starvation.
    Plant Physiol., 2016. 170(1): p. 499-514
    [PMID:26586833]
  18. Aleksza D,Horváth GV,Sándor G,Szabados L
    Proline Accumulation Is Regulated by Transcription Factors Associated with Phosphate Starvation.
    Plant Physiol., 2017. 175(1): p. 555-567
    [PMID:28765275]