PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G25160.1
Common NameF21J6.6, ZFP3
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family C2H2
Protein Properties Length: 235aa    MW: 26351 Da    PI: 6.9065
Description zinc finger protein 3
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G25160.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H2157e-056183123
                 EEETTTTEEESSHHHHHHHHHHT CS
      zf-C2H2  1 ykCpdCgksFsrksnLkrHirtH 23
                 ++C++C ++F ++  L  H++ H
  AT5G25160.1 61 FSCNYCQRTFYSSQALGGHQNAH 83
                 89******************988 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.602.5E-45287IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576672.59E-75688No hitNo description
PROSITE profilePS5015711.6356188IPR007087Zinc finger, C2H2
PROSITE patternPS0002806383IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008270Molecular Functionzinc ion binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000037anatomyshoot apex
PO:0009005anatomyroot
PO:0009046anatomyflower
PO:0020100anatomyhypocotyl
PO:0007611developmental stagepetal differentiation and expansion stage
Sequence ? help Back to Top
Protein Sequence    Length: 235 aa     Download sequence    Send to blast
MDASIVSSST AFPYQDSLNQ SIEDEERDVH NSSHELNLID CIDDTTSIVN ESTTSTEQKL  60
FSCNYCQRTF YSSQALGGHQ NAHKRERTLA KRGQRMAASA SAFGHPYGFS PLPFHGQYNN  120
HRSLGIQAHS ISHKLSSYNG FGGHYGQINW SRLPFDQQPA IGKFPSMDNF HHHHHQMMMM  180
APSVNSRSNN IDSPSNTGRV LEGSPTLEQW HGDKGLLLST SHHEEQQKLD LSLKL
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.16420.0root
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible246933_at0.0
Expression AtlasAT5G25160-
AtGenExpressAT5G25160-
ATTED-IIAT5G25160-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in the chalaze of seeds, hypocotyls, cotyledons, roots, emerging lateral roots, leaves, sepals and stamens. These data suggest that ZFP3 is expressed in most organs, showing high expression in vascular tissues.
Functional Description ? help Back to Top
Source Description
TAIREncodes a zinc finger protein containing only a single zinc finger.
UniProtActs as negative regulator of abscisic acid (ABA) signaling during germination and early seedling development. Involved in the regulation of vegetative development and fertility. Modulates red light signaling in seedling photomorphogenesis. {ECO:0000269|PubMed:24808098}.
Function -- GeneRIF ? help Back to Top
  1. results suggest that ZFP3 is involved in salt and osmotic stress response.
    [PMID: 27977750]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G25160.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by abscisic acid (ABA). {ECO:0000269|PubMed:24808098}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G25160
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC0062590.0AC006259.1 Arabidopsis thaliana BAC F21J6 from chromosome V, containing KNAT3 and mapping near 60.5 cM, complete sequence.
GenBankAK2277060.0AK227706.1 Arabidopsis thaliana mRNA for ZFP3 zinc finger protein, complete cds, clone: RAFL14-29-I08.
GenBankATHZFPC0.0L39646.1 Arabidopsis thaliana zinc finger protein (ZFP3) mRNA, complete cds.
GenBankBT0083080.0BT008308.1 Arabidopsis thaliana At5g25160 gene, complete cds.
GenBankCP0026880.0CP002688.1 Arabidopsis thaliana chromosome 5 sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_197898.11e-177zinc finger protein 3
SwissprotQ392621e-178ZFP3_ARATH; Zinc finger protein 3
TrEMBLA0A384LK931e-176A0A384LK93_ARATH; ZFP3
TrEMBLQ0WT561e-176Q0WT56_ARATH; ZFP3 zinc finger protein
STRINGAT5G25160.11e-177(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM18932771
Representative plantOGRP8215137
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  3. Englbrecht CC,Schoof H,B
    Conservation, diversification and expansion of C2H2 zinc finger proteins in the Arabidopsis thaliana genome.
    BMC Genomics, 2004. 5(1): p. 39
    [PMID:15236668]
  4. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  5. Cao D,Cheng H,Wu W,Soo HM,Peng J
    Gibberellin mobilizes distinct DELLA-dependent transcriptomes to regulate seed germination and floral development in Arabidopsis.
    Plant Physiol., 2006. 142(2): p. 509-25
    [PMID:16920880]
  6. Gaudinier A, et al.
    Enhanced Y1H assays for Arabidopsis.
    Nat. Methods, 2011. 8(12): p. 1053-5
    [PMID:22037706]
  7. Joseph MP, et al.
    The Arabidopsis ZINC FINGER PROTEIN3 Interferes with Abscisic Acid and Light Signaling in Seed Germination and Plant Development.
    Plant Physiol., 2014. 165(3): p. 1203-1220
    [PMID:24808098]
  8. Zhang A, et al.
    The Arabidopsis Gene zinc finger protein 3(ZFP3) Is Involved in Salt Stress and Osmotic Stress Response.
    PLoS ONE, 2016. 11(12): p. e0168367
    [PMID:27977750]
  9. Tague BW,Goodman HM
    Characterization of a family of Arabidopsis zinc finger protein cDNAs.
    Plant Mol. Biol., 1995. 28(2): p. 267-79
    [PMID:7599312]