PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G17430.1
Common NameAIL2, BBM, T10B6.90
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family AP2
Protein Properties Length: 584aa    MW: 64545.2 Da    PI: 6.4343
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G17430.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP248.32.5e-15209268155
          AP2   1 sgykGVrwdkkrgrWvAeIrd.pse.ng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 
                  s y+GV++++++gr++A+++d  ++  g  ++ ++++lg ++ +e+Aa+a++ a++k++g
  AT5G17430.1 209 SIYRGVTRHRWTGRYEAHLWDnSCKrEGqtRKgRQVYLGGYDKEEKAARAYDLAALKYWG 268
                  57*******************999975578446*************************98 PP

2AP251.13.3e-16311362155
          AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                  s y+GV+++++ grW A+I  +     +k  +lg+fgt eeAa+a++ a+ k++g
  AT5G17430.1 311 SIYRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFGTQEEAAEAYDIAAIKFRG 362
                  57****************988532...5************************998 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541713.01E-17209278IPR016177DNA-binding domain
CDDcd000181.75E-21209278No hitNo description
PfamPF008477.8E-12209268IPR001471AP2/ERF domain
PROSITE profilePS5103219.164210276IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.109.7E-16210277IPR001471AP2/ERF domain
SMARTSM003801.3E-29210282IPR001471AP2/ERF domain
PRINTSPR003674.1E-6211222IPR001471AP2/ERF domain
SuperFamilySSF541711.7E-17311371IPR016177DNA-binding domain
CDDcd000184.33E-24311370No hitNo description
PfamPF008474.1E-11311362IPR001471AP2/ERF domain
PROSITE profilePS5103218.742312370IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.9E-17312370IPR001471AP2/ERF domain
SMARTSM003809.7E-33312376IPR001471AP2/ERF domain
PRINTSPR003674.1E-6352372IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0007275Biological Processmulticellular organism development
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000016anatomylateral root primordium
PO:0000025anatomyroot tip
PO:0000084anatomyplant sperm cell
PO:0009009anatomyplant embryo
Sequence ? help Back to Top
Protein Sequence    Length: 584 aa     Download sequence    Send to blast
MNSMNNWLGF SLSPHDQNHH RTDVDSSTTR TAVDVAGGYC FDLAAPSDES SAVQTSFLSP  60
FGVTLEAFTR DNNSHSRDWD INGGACNNIN NNEQNGPKLE NFLGRTTTIY NTNETVVDGN  120
GDCGGGDGGG GGSLGLSMIK TWLSNHSVAN ANHQDNGNGA RGLSLSMNSS TSDSNNYNNN  180
DDVVQEKTIV DVVETTPKKT IESFGQRTSI YRGVTRHRWT GRYEAHLWDN SCKREGQTRK  240
GRQVYLGGYD KEEKAARAYD LAALKYWGTT TTTNFPLSEY EKEVEEMKHM TRQEYVASLR  300
RKSSGFSRGA SIYRGVTRHH QHGRWQARIG RVAGNKDLYL GTFGTQEEAA EAYDIAAIKF  360
RGLSAVTNFD MNRYNVKAIL ESPSLPIGSS AKRLKDVNNP VPAMMISNNV SESANNVSGW  420
QNTAFQHHQG MDLSLLQQQQ ERYVGYYNGG NLSTESTRVC FKQEEEQQHF LRNSPSHMTN  480
VDHHSSTSDD SVTVCGNVVS YGGYQGFAIP VGTSVNYDPF TAAEIAYNAR NHYYYAQHQQ  540
QQQIQQSPGG DFPVAISNNH SSNMYFHGEG GGEGAPTFSV WNDT
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO1865236380.0
Genevisible246426_at0.0
Expression AtlasAT5G17430-
AtGenExpressAT5G17430-
ATTED-IIAT5G17430-
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in embryo throughout embryogenesis. Also present in free nuclear endosperm, but disappears once endosperm cellularization begins. {ECO:0000269|PubMed:12172019}.
UniprotTISSUE SPECIFICITY: Mostly expressed in developing seeds. Also expressed in roots, seedlings, and siliques, and, at low levels, in leaves. {ECO:0000269|PubMed:12172019, ECO:0000269|PubMed:15988559}.
Functional Description ? help Back to Top
Source Description
TAIREncodes an AP2-domain containing protein similar to ANT. Expressed in embryos and lateral root primordium.
UniProtTranscription factor that promotes cell proliferation, differentiation and morphogenesis, especially during embryogenesis. {ECO:0000269|PubMed:12172019}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00610ChIP-seqSRX377734Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G17430.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT3G44750(A), AT5G03740(A), AT5G22650(A)
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G17430
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankEF6878430.0EF687843.1 Arabidopsis thaliana ecotype C24 BABY BOOM (BBM) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_197245.20.0Integrase-type DNA-binding superfamily protein
SwissprotQ6PQQ40.0BBM_ARATH; AP2-like ethylene-responsive transcription factor BBM
TrEMBLA7L9U10.0A7L9U1_ARATH; BABY BOOM
STRINGAT5G17430.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM86552737
Representative plantOGRP11217209
Publications ? help Back to Top
  1. Todd J,Post-Beittenmiller D,Jaworski JG
    KCS1 encodes a fatty acid elongase 3-ketoacyl-CoA synthase affecting wax biosynthesis in Arabidopsis thaliana.
    Plant J., 1999. 17(2): p. 119-30
    [PMID:10074711]
  2. Krizek BA,Prost V,Macias A
    AINTEGUMENTA promotes petal identity and acts as a negative regulator of AGAMOUS.
    Plant Cell, 2000. 12(8): p. 1357-66
    [PMID:10948255]
  3. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  4. Boutilier K, et al.
    Ectopic expression of BABY BOOM triggers a conversion from vegetative to embryonic growth.
    Plant Cell, 2002. 14(8): p. 1737-49
    [PMID:12172019]
  5. Zhou C, et al.
    Expression and function of HD2-type histone deacetylases in Arabidopsis development.
    Plant J., 2004. 38(5): p. 715-24
    [PMID:15144374]
  6. Masaki T, et al.
    ACTIVATOR of Spomin::LUC1/WRINKLED1 of Arabidopsis thaliana transactivates sugar-inducible promoters.
    Plant Cell Physiol., 2005. 46(4): p. 547-56
    [PMID:15753106]
  7. Casson S,Spencer M,Walker K,Lindsey K
    Laser capture microdissection for the analysis of gene expression during embryogenesis of Arabidopsis.
    Plant J., 2005. 42(1): p. 111-23
    [PMID:15773857]
  8. Nawy T, et al.
    Transcriptional profile of the Arabidopsis root quiescent center.
    Plant Cell, 2005. 17(7): p. 1908-25
    [PMID:15937229]
  9. Nole-Wilson S,Tranby TL,Krizek BA
    AINTEGUMENTA-like (AIL) genes are expressed in young tissues and may specify meristematic or division-competent states.
    Plant Mol. Biol., 2005. 57(5): p. 613-28
    [PMID:15988559]
  10. Kim S,Soltis PS,Wall K,Soltis DE
    Phylogeny and domain evolution in the APETALA2-like gene family.
    Mol. Biol. Evol., 2006. 23(1): p. 107-20
    [PMID:16151182]
  11. Nakano T,Suzuki K,Fujimura T,Shinshi H
    Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
    Plant Physiol., 2006. 140(2): p. 411-32
    [PMID:16407444]
  12. Brand L, et al.
    A versatile and reliable two-component system for tissue-specific gene induction in Arabidopsis.
    Plant Physiol., 2006. 141(4): p. 1194-204
    [PMID:16896232]
  13. Panjabi P,Burma PK,Pental D
    Use of the transposable element Ac/Ds in conjunction with Spm/dSpm for gene tagging allows extensive genome coverage with a limited number of starter lines: functional analysis of a four-element system in Arabidopsis thaliana.
    Mol. Genet. Genomics, 2006. 276(6): p. 533-43
    [PMID:17004082]
  14. Galinha C, et al.
    PLETHORA proteins as dose-dependent master regulators of Arabidopsis root development.
    Nature, 2007. 449(7165): p. 1053-7
    [PMID:17960244]
  15. Wang X, et al.
    Overexpression of PGA37/MYB118 and MYB115 promotes vegetative-to-embryonic transition in Arabidopsis.
    Cell Res., 2009. 19(2): p. 224-35
    [PMID:18695688]
  16. El Ouakfaoui S, et al.
    Control of somatic embryogenesis and embryo development by AP2 transcription factors.
    Plant Mol. Biol., 2010. 74(4-5): p. 313-26
    [PMID:20798978]
  17. Lutz KA,Azhagiri A,Maliga P
    Transplastomics in Arabidopsis: progress toward developing an efficient method.
    Methods Mol. Biol., 2011. 774: p. 133-47
    [PMID:21822837]
  18. Causier B,Ashworth M,Guo W,Davies B
    The TOPLESS interactome: a framework for gene repression in Arabidopsis.
    Plant Physiol., 2012. 158(1): p. 423-38
    [PMID:22065421]
  19. Aoyama T, et al.
    AP2-type transcription factors determine stem cell identity in the moss Physcomitrella patens.
    Development, 2012. 139(17): p. 3120-9
    [PMID:22833122]
  20. Efroni I, et al.
    Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses.
    Dev. Cell, 2013. 24(4): p. 438-45
    [PMID:23449474]
  21. Horstman A,Willemsen V,Boutilier K,Heidstra R
    AINTEGUMENTA-LIKE proteins: hubs in a plethora of networks.
    Trends Plant Sci., 2014. 19(3): p. 146-57
    [PMID:24280109]
  22. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  23. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]
  24. Florez SL,Erwin RL,Maximova SN,Guiltinan MJ,Curtis WR
    Enhanced somatic embryogenesis in Theobroma cacao using the homologous BABY BOOM transcription factor.
    BMC Plant Biol., 2015. 15: p. 121
    [PMID:25976599]
  25. Lutz KA,Martin C,Khairzada S,Maliga P
    Steroid-inducible BABY BOOM system for development of fertile Arabidopsis thaliana plants after prolonged tissue culture.
    Plant Cell Rep., 2015. 34(10): p. 1849-56
    [PMID:26156330]
  26. Horstman A, et al.
    The BABY BOOM Transcription Factor Activates the LEC1-ABI3-FUS3-LEC2 Network to Induce Somatic Embryogenesis.
    Plant Physiol., 2017. 175(2): p. 848-857
    [PMID:28830937]
  27. Du Y,Scheres B
    PLETHORA transcription factors orchestrate de novo organ patterning during Arabidopsis lateral root outgrowth.
    Proc. Natl. Acad. Sci. U.S.A., 2017. 114(44): p. 11709-11714
    [PMID:29078398]
  28. Horstman A,Bemer M,Boutilier K
    A transcriptional view on somatic embryogenesis.
    Regeneration (Oxf), 2017. 4(4): p. 201-216
    [PMID:29299323]
  29. Klucher KM,Chow H,Reiser L,Fischer RL
    The AINTEGUMENTA gene of Arabidopsis required for ovule and female gametophyte development is related to the floral homeotic gene APETALA2.
    Plant Cell, 1996. 8(2): p. 137-53
    [PMID:8742706]
  30. Elliott RC, et al.
    AINTEGUMENTA, an APETALA2-like gene of Arabidopsis with pleiotropic roles in ovule development and floral organ growth.
    Plant Cell, 1996. 8(2): p. 155-68
    [PMID:8742707]
  31. Okamuro JK,Caster B,Villarroel R,Van Montagu M,Jofuku KD
    The AP2 domain of APETALA2 defines a large new family of DNA binding proteins in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 1997. 94(13): p. 7076-81
    [PMID:9192694]
  32. Schneitz K,Baker SC,Gasser CS,Redweik A
    Pattern formation and growth during floral organogenesis: HUELLENLOS and AINTEGUMENTA are required for the formation of the proximal region of the ovule primordium in Arabidopsis thaliana.
    Development, 1998. 125(14): p. 2555-63
    [PMID:9636071]