PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G07580.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family ERF
Protein Properties Length: 274aa    MW: 31159.9 Da    PI: 5.6601
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G07580.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP251.42.6e-16176226255
          AP2   2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                  +y+GVr+++ +g+++AeIrdp +  k  r++lg+f +  +Aa+a++ a+ kl+g
  AT5G07580.1 176 HYRGVRRRP-WGKFAAEIRDPAK--KGSRIWLGTFESDVDAARAYDCAAFKLRG 226
                  7********.**********954..34**********99*************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.730.101.2E-30175235IPR001471AP2/ERF domain
SuperFamilySSF541713.2E-22176235IPR016177DNA-binding domain
PfamPF008474.4E-11176226IPR001471AP2/ERF domain
SMARTSM003808.3E-36176240IPR001471AP2/ERF domain
CDDcd000185.62E-30176234No hitNo description
PROSITE profilePS5103224.487176234IPR001471AP2/ERF domain
PRINTSPR003675.9E-13177188IPR001471AP2/ERF domain
PRINTSPR003675.9E-13216236IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009409Biological Processresponse to cold
GO:0009414Biological Processresponse to water deprivation
GO:0009737Biological Processresponse to abscisic acid
GO:0009873Biological Processethylene-activated signaling pathway
GO:1902074Biological Processresponse to salt
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 274 aa     Download sequence    Send to blast
MTPSLKPLRE RQNHSFFFVS LPHPWLLKSC DYLLVSFLFS FPLLYKNQNI HSFCSIITCR  60
FFLSFVKMAS FEESSDLEAI QSHLLEDLLV CDGFMGDFDF DASFVSGLWC IEPHVPKQEP  120
DSPVLDPDSF VNEFLQVEGE SSSSSSPELN SSSSTYETDQ SVKKAERFEE EVDARHYRGV  180
RRRPWGKFAA EIRDPAKKGS RIWLGTFESD VDAARAYDCA AFKLRGRKAV LNFPLDAGKY  240
EAPANSGRKR KRSDVHEELQ RTQSNSSSSS CDAF
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2gcc_A1e-28174235364ATERF1
3gcc_A1e-28174235364ATERF1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.264190.0floral meristem| root
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO795084050.0
Genevisible250582_at0.0
Expression AtlasAT5G07580-
AtGenExpressAT5G07580-
ATTED-IIAT5G07580-
Functional Description ? help Back to Top
Source Description
TAIRencodes a member of the ERF (ethylene response factor) subfamily B-3 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 18 members in this subfamily including ATERF-1, ATERF-2, AND ATERF-5.
UniProtProbably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.
Function -- GeneRIF ? help Back to Top
  1. We propose a model whereby vascular cell division is regulated both by PXY signalling and ethylene/ERF signalling
    [PMID: 23166504]
  2. DEWAX2-mediated transcriptional repression may contribute to the total wax load in Arabidopsis leaves.[DEWAX2]
    [PMID: 29425344]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G07580.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDethylene
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G07580
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0100700.0AB010070.1 Arabidopsis thaliana genomic DNA, chromosome 5, P1 clone:MBK20.
GenBankAL1639120.0AL163912.1 Arabidopsis thaliana DNA chromosome 5, BAC clone T2I1 (ESSA project).
GenBankCP0026880.0CP002688.1 Arabidopsis thaliana chromosome 5 sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_196375.31e-149ethylene-responsive transcription factor
SwissprotQ9LY051e-150EF106_ARATH; Ethylene-responsive transcription factor ERF106
TrEMBLA0A178UH671e-147A0A178UH67_ARATH; Uncharacterized protein
STRINGAT5G07580.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM32292766
Representative plantOGRP6161718
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Gutierrez RA,Ewing RM,Cherry JM,Green PJ
    Identification of unstable transcripts in Arabidopsis by cDNA microarray analysis: rapid decay is associated with a group of touch- and specific clock-controlled genes.
    Proc. Natl. Acad. Sci. U.S.A., 2002. 99(17): p. 11513-8
    [PMID:12167669]
  3. Schein M,Yang Z,Mitchell-Olds T,Schmid KJ
    Rapid evolution of a pollen-specific oleosin-like gene family from Arabidopsis thaliana and closely related species.
    Mol. Biol. Evol., 2004. 21(4): p. 659-69
    [PMID:14739246]
  4. Fiebig A,Kimport R,Preuss D
    Comparisons of pollen coat genes across Brassicaceae species reveal rapid evolution by repeat expansion and diversification.
    Proc. Natl. Acad. Sci. U.S.A., 2004. 101(9): p. 3286-91
    [PMID:14970339]
  5. Liu F, et al.
    Global transcription profiling reveals comprehensive insights into hypoxic response in Arabidopsis.
    Plant Physiol., 2005. 137(3): p. 1115-29
    [PMID:15734912]
  6. Ehlting J, et al.
    Global transcript profiling of primary stems from Arabidopsis thaliana identifies candidate genes for missing links in lignin biosynthesis and transcriptional regulators of fiber differentiation.
    Plant J., 2005. 42(5): p. 618-40
    [PMID:15918878]
  7. Mazzella MA, et al.
    Phytochrome control of the Arabidopsis transcriptome anticipates seedling exposure to light.
    Plant Cell, 2005. 17(9): p. 2507-16
    [PMID:16024587]
  8. Branco-Price C,Kawaguchi R,Ferreira RB,Bailey-Serres J
    Genome-wide analysis of transcript abundance and translation in Arabidopsis seedlings subjected to oxygen deprivation.
    Ann. Bot., 2005. 96(4): p. 647-60
    [PMID:16081496]
  9. Wang J, et al.
    Genomewide nonadditive gene regulation in Arabidopsis allotetraploids.
    Genetics, 2006. 172(1): p. 507-17
    [PMID:16172500]
  10. Pischke MS,Huttlin EL,Hegeman AD,Sussman MR
    A transcriptome-based characterization of habituation in plant tissue culture.
    Plant Physiol., 2006. 140(4): p. 1255-78
    [PMID:16489130]
  11. Truman W,de Zabala MT,Grant M
    Type III effectors orchestrate a complex interplay between transcriptional networks to modify basal defence responses during pathogenesis and resistance.
    Plant J., 2006. 46(1): p. 14-33
    [PMID:16553893]
  12. van der Graaff E, et al.
    Transcription analysis of arabidopsis membrane transporters and hormone pathways during developmental and induced leaf senescence.
    Plant Physiol., 2006. 141(2): p. 776-92
    [PMID:16603661]
  13. Broekgaarden C, et al.
    Genotypic variation in genome-wide transcription profiles induced by insect feeding: Brassica oleracea--Pieris rapae interactions.
    BMC Genomics, 2007. 8: p. 239
    [PMID:17640338]
  14. Etchells JP,Provost CM,Turner SR
    Plant vascular cell division is maintained by an interaction between PXY and ethylene signalling.
    PLoS Genet., 2012. 8(11): p. e1002997
    [PMID:23166504]
  15. Kim H,Go YS,Suh MC
    DEWAX2 Transcription Factor Negatively Regulates Cuticular Wax Biosynthesis in Arabidopsis Leaves.
    Plant Cell Physiol., 2018. 59(5): p. 966-977
    [PMID:29425344]
  16. Riechmann JL,Meyerowitz EM
    The AP2/EREBP family of plant transcription factors.
    Biol. Chem., 1998. 379(6): p. 633-46
    [PMID:9687012]