PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G07310.1
Common NameERF115, T2I1.20
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family ERF
Protein Properties Length: 263aa    MW: 29405.7 Da    PI: 7.0869
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G07310.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP261.61.7e-1991140255
          AP2   2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 
                  +y+GVr+++ +g+W+AeIrdp     + +r++lg+f tae Aa a+++a++k++g
  AT5G07310.1  91 HYRGVRQRP-WGKWAAEIRDPQ----KaARVWLGTFETAEAAALAYDNAALKFKG 140
                  7********.**********93....36************************987 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.730.109.2E-3390149IPR001471AP2/ERF domain
PROSITE profilePS5103224.92291148IPR001471AP2/ERF domain
SuperFamilySSF541714.9E-2291149IPR016177DNA-binding domain
PfamPF008472.2E-1391140IPR001471AP2/ERF domain
CDDcd000182.57E-2391149No hitNo description
SMARTSM003808.8E-3791154IPR001471AP2/ERF domain
PRINTSPR003671.7E-1192103IPR001471AP2/ERF domain
PRINTSPR003671.7E-11114130IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009873Biological Processethylene-activated signaling pathway
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 263 aa     Download sequence    Send to blast
MANSGNYGKR PFRGDESDEK KEADDDENIF PFFSARSQYD MRAMVSALTQ VIGNQSSSHD  60
NNQHQPVVYN QQDPNPPAPP TQDQGLLRKR HYRGVRQRPW GKWAAEIRDP QKAARVWLGT  120
FETAEAAALA YDNAALKFKG SKAKLNFPER AQLASNTSTT TGPPNYYSSN NQIYYSNPQT  180
NPQTIPYFNQ YYYNQYLHQG GNSNDALSYS LAGGETGGSM YNHQTLSTTN SSSSGGSSRQ  240
QDDEQDYARY LRFGDSSPPN SGF
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2gcc_A4e-2690151466ATERF1
3gcc_A4e-2690151466ATERF1
Search in ModeBase
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO184154580.0
Genevisible250622_at0.0
Expression AtlasAT5G07310-
AtGenExpressAT5G07310-
ATTED-IIAT5G07310-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Restricted to dividing quiescent center cells. {ECO:0000269|PubMed:24158907}.
Functional Description ? help Back to Top
Source Description
TAIRencodes a member of the ERF (ethylene response factor) subfamily B-4 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 7 members in this subfamily.
UniProtActs as a transcriptional activator of the phytosulfokine PSK5 peptide hormone. Binds to the GCC-box pathogenesis-related promoter element. Rate-limiting factor of quiescent center cell division active when surrounding stem cells are damaged. Is a proteolytic target of APC/C-FZR1 complex. {ECO:0000269|PubMed:24158907}.
Function -- GeneRIF ? help Back to Top
  1. Together, these two antagonistic mechanisms delimit ERF115 activity, which is called upon when surrounding stem cells are damaged, revealing a cell cycle regulatory mechanism accounting for stem cell niche longevity.
    [PMID: 24158907]
  2. The heterodimeric transcription factor complex ETHYLENE RESPONSE FACTOR115 (ERF115)-PHYTOCHROME A SIGNAL TRANSDUCTION1 (PAT1) sustains meristem function by promoting cell renewal after stem cell loss.
    [PMID: 27797356]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00495DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G07310.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by brassinosteroid, but not regulated by ethylene. {ECO:0000269|PubMed:24158907}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Interaction ? help Back to Top
Source Intact With
IntActSearch Q9LY29
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G07310
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY5608850.0AY560885.1 Arabidopsis thaliana putative AP2/EREBP transcription factor (At5g07310) mRNA, complete cds.
GenBankBT0257170.0BT025717.1 Arabidopsis thaliana At5g07310 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_196348.10.0Integrase-type DNA-binding superfamily protein
SwissprotQ9LY290.0EF115_ARATH; Ethylene-responsive transcription factor ERF115
TrEMBLA0A178UG220.0A0A178UG22_ARATH; Uncharacterized protein
STRINGAT5G07310.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM52921851
Representative plantOGRP6161718
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Lee BH,Henderson DA,Zhu JK
    The Arabidopsis cold-responsive transcriptome and its regulation by ICE1.
    Plant Cell, 2005. 17(11): p. 3155-75
    [PMID:16214899]
  3. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  4. Nakano T,Suzuki K,Fujimura T,Shinshi H
    Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
    Plant Physiol., 2006. 140(2): p. 411-32
    [PMID:16407444]
  5. Ma S,Gong Q,Bohnert HJ
    Dissecting salt stress pathways.
    J. Exp. Bot., 2006. 57(5): p. 1097-107
    [PMID:16510518]
  6. Underwood BA,Vanderhaeghen R,Whitford R,Town CD,Hilson P
    Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.
    Plant Biotechnol. J., 2006. 4(3): p. 317-24
    [PMID:17147637]
  7. Van Leene J, et al.
    Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana.
    Mol. Syst. Biol., 2010. 6: p. 397
    [PMID:20706207]
  8. Heyman J, et al.
    ERF115 controls root quiescent center cell division and stem cell replenishment.
    Science, 2013. 342(6160): p. 860-3
    [PMID:24158907]
  9. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  10. Zhang Y, et al.
    Shade avoidance 6 encodes an Arabidopsis flap endonuclease required for maintenance of genome integrity and development.
    Nucleic Acids Res., 2016. 44(3): p. 1271-84
    [PMID:26721386]
  11. Zhang Y, et al.
    TOPOISOMERASE1α Acts through Two Distinct Mechanisms to Regulate Stele and Columella Stem Cell Maintenance.
    Plant Physiol., 2016. 171(1): p. 483-93
    [PMID:26969721]
  12. Heyman J, et al.
    The heterodimeric transcription factor complex ERF115-PAT1 grants regeneration competence.
    Nat Plants, 2016. 2(11): p. 16165
    [PMID:27797356]
  13. Kong X, et al.
    PHB3 Maintains Root Stem Cell Niche Identity through ROS-Responsive AP2/ERF Transcription Factors in Arabidopsis.
    Cell Rep, 2018. 22(5): p. 1350-1363
    [PMID:29386120]