PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G01900.1
Common NameATWRKY62, T20L15.170, WRKY62
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family WRKY
Protein Properties Length: 263aa    MW: 30442.5 Da    PI: 6.3568
Description WRKY DNA-binding protein 62
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G01900.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY742e-23110170259
                  --SS-EEEEEEE--TT-SS-EEEEEE-ST...T---EEEEEE-SSSTTEEEEEEES--SS- CS
         WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsa...gCpvkkkversaedpkvveitYegeHnhe 59 
                  +Dg+ WrKYGqK++k+se+ rsYY+C+++   +C++kk+v++ +++p +  +tY g+H ++
  AT5G01900.1 110 HDGFLWRKYGQKQIKESEYQRSYYKCAYTkdqNCEAKKQVQKIQHNPPLYSTTYFGQHICQ 170
                  6**************************988899*************************986 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.801.6E-23101170IPR003657WRKY domain
PROSITE profilePS5081120.426104167IPR003657WRKY domain
SuperFamilySSF1182902.75E-22105171IPR003657WRKY domain
SMARTSM007747.0E-34109171IPR003657WRKY domain
PfamPF031061.9E-22111170IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009863Biological Processsalicylic acid mediated signaling pathway
GO:0042742Biological Processdefense response to bacterium
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005515Molecular Functionprotein binding
GO:0043565Molecular Functionsequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000293anatomyguard cell
Sequence ? help Back to Top
Protein Sequence    Length: 263 aa     Download sequence    Send to blast
MNSCQQKAME KLLHGHGCAN QLLIMDQTES DSSMEREDLA KSVLHCFSDA LSILIDTNDH  60
QDDQSNNSSP QDSSPVLESS RKPLHKRGRK TSMAESSDYH RHESSTPIYH DGFLWRKYGQ  120
KQIKESEYQR SYYKCAYTKD QNCEAKKQVQ KIQHNPPLYS TTYFGQHICQ LHQAYATFPI  180
DTSDFEEHEG SHMIRFGHPN ISFSSSTSNL RQHQNHQDRI KDEYMKPVIA EDWSPSQWMS  240
SEVALAVEAF EFNPFWTSHD LSS
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO425675810.0
Expression AtlasAT5G01900-
AtGenExpressAT5G01900-
Functional Description ? help Back to Top
Source Description
TAIRmember of WRKY Transcription Factor; Group III
UniProtTranscription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250}.
Function -- GeneRIF ? help Back to Top
  1. WRKY62, a member of WRKY group III transcription factors, was induced by methyl jasmonate and salicylic acid treatment; it acts downstream of cytosolic NPR1 and negatively regulates JA-responsive gene expression.
    [PMID: 17510065]
  2. WRKY38 and WRKY62 are transcriptional activators in plant cells that function additively as negative regulators of plant basal defense, but their activation activities are abolished by overexpressed HDA19.
    [PMID: 18776063]
  3. results suggest that PKS5 functions at the upstream of NPR1 and might mediate expression of WRKY38 and WRKY62 possibly by interacting with and phosphorylating NPR1.
    [PMID: 20621018]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00070PBM25215497Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G01900.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By salicylic acid. {ECO:0000269|PubMed:11449049}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT1G64280(A), AT2G14610(R), AT3G45140(R), AT5G24770(R)
Interaction ? help Back to Top
Source Intact With
IntActSearch Q9LZV6
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G01900
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB4937300.0AB493730.1 Arabidopsis thaliana At5g01900 mRNA for hypothetical protein, partial cds, clone: RAAt5g01900.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_195810.20.0putative WRKY transcription factor 62
SwissprotQ9LZV60.0WRK62_ARATH; Probable WRKY transcription factor 62
TrEMBLC0SVM70.0C0SVM7_ARATH; Putative uncharacterized protein At5g01900 (Fragment)
STRINGAT5G01900.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP1417875
MalvidsOGEM145051522
Publications ? help Back to Top
  1. Eulgem T,Rushton PJ,Robatzek S,Somssich IE
    The WRKY superfamily of plant transcription factors.
    Trends Plant Sci., 2000. 5(5): p. 199-206
    [PMID:10785665]
  2. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  3. Yu D,Chen C,Chen Z
    Evidence for an important role of WRKY DNA binding proteins in the regulation of NPR1 gene expression.
    Plant Cell, 2001. 13(7): p. 1527-40
    [PMID:11449049]
  4. Miao Y,Laun T,Zimmermann P,Zentgraf U
    Targets of the WRKY53 transcription factor and its role during leaf senescence in Arabidopsis.
    Plant Mol. Biol., 2004. 55(6): p. 853-67
    [PMID:15604721]
  5. Li P, et al.
    Effects of chronic ozone exposure on gene expression in Arabidopsis thaliana ecotypes and in Thellungiella halophila.
    Plant Cell Environ., 2006. 29(5): p. 854-68
    [PMID:17087469]
  6. Mao P,Duan M,Wei C,Li Y
    WRKY62 transcription factor acts downstream of cytosolic NPR1 and negatively regulates jasmonate-responsive gene expression.
    Plant Cell Physiol., 2007. 48(6): p. 833-42
    [PMID:17510065]
  7. Kim KC,Lai Z,Fan B,Chen Z
    Arabidopsis WRKY38 and WRKY62 transcription factors interact with histone deacetylase 19 in basal defense.
    Plant Cell, 2008. 20(9): p. 2357-71
    [PMID:18776063]
  8. Xie C,Zhou X,Deng X,Guo Y
    PKS5, a SNF1-related kinase, interacts with and phosphorylates NPR1, and modulates expression of WRKY38 and WRKY62.
    J Genet Genomics, 2010. 37(6): p. 359-69
    [PMID:20621018]
  9. Jeong HJ, et al.
    Nonsense-mediated mRNA decay factors, UPF1 and UPF3, contribute to plant defense.
    Plant Cell Physiol., 2011. 52(12): p. 2147-56
    [PMID:22025558]
  10. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]