PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT4G38960.1
Common NameBBX19, DBB1B, F19H22.60, STH5
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family DBB
Protein Properties Length: 183aa    MW: 20146.6 Da    PI: 5.3013
Description DBB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT4G38960.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-B_box20.68.9e-07433534
     zf-B_box  5 kCpeHeekelqlfCedCqqllCedClleeH 34
                  C+ +e+  +++fC  ++  lC+ C ++ H
  AT4G38960.1  4 LCDACENAAAIIFCAADEAALCRPCDEKVH 33
                 6*******9******************998 PP

2zf-B_box26.71.2e-085291237
     zf-B_box  2 eerkCpeHeekelqlfCedCqqllCedClleeHkg....H 37
                 ++++C+ +e+ ++ ++Ce +++ lC +C +  H g    H
  AT4G38960.1 52 NAPCCDICENAPAFFYCEIDGSSLCLQCDMVVHVGgkrtH 91
                 789***************************9996555556 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5011910.267147IPR000315B-box-type zinc finger
CDDcd000216.00E-6345No hitNo description
SMARTSM003361.4E-7447IPR000315B-box-type zinc finger
PfamPF006432.7E-5442IPR000315B-box-type zinc finger
SMARTSM003362.2E-125196IPR000315B-box-type zinc finger
PROSITE profilePS501198.9165196IPR000315B-box-type zinc finger
PfamPF006431.7E-65291IPR000315B-box-type zinc finger
CDDcd000219.76E-85696No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0007623Biological Processcircadian rhythm
GO:0010100Biological Processnegative regulation of photomorphogenesis
GO:0010228Biological Processvegetative to reproductive phase transition of meristem
GO:0005634Cellular Componentnucleus
GO:0000989Molecular Functiontranscription factor activity, transcription factor binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005515Molecular Functionprotein binding
GO:0008270Molecular Functionzinc ion binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020100anatomyhypocotyl
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 183 aa     Download sequence    Send to blast
MRILCDACEN AAAIIFCAAD EAALCRPCDE KVHMCNKLAS RHVRVGLAEP SNAPCCDICE  60
NAPAFFYCEI DGSSLCLQCD MVVHVGGKRT HGRFLLLRQR IEFPGDKPKE NNTRDNLQNQ  120
RVSTNGNGEA NGKIDDEMID LNANPQRVHE PSSNNNGIDV NNENNHEPAG LVPVGPFKRE  180
SEK
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.726070.0bud| flower| leaf| root| seed| silique
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible252917_at1e-155
Expression AtlasAT4G38960-
AtGenExpressAT4G38960-
ATTED-IIAT4G38960-
Functional Description ? help Back to Top
Source Description
UniProtActs as negative regulator of seedling photomorphogenesis. {ECO:0000269|PubMed:18540109}.
Function -- GeneRIF ? help Back to Top
  1. Results implicate BBX19 as a circadian clock output that depletes the active CO pool to accurately monitor daylength and precisely time FT expression.
    [PMID: 25228341]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT4G38960.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Interaction ? help Back to Top
Source Intact With
BioGRIDAT5G15840
IntActSearch C0SVM5
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT4G38960
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB4937280.0AB493728.1 Arabidopsis thaliana At4g38960 mRNA for hypothetical protein, partial cds, clone: RAAt4g38960.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_195607.21e-133B-box type zinc finger-containing protein
SwissprotC0SVM51e-135BBX19_ARATH; B-box zinc finger protein 19
TrEMBLD7MFQ51e-129D7MFQ5_ARALL; Zinc finger (B-box type) family protein
STRINGscaffold_700091.11e-129(Arabidopsis lyrata)
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Fowler S,Thomashow MF
    Arabidopsis transcriptome profiling indicates that multiple regulatory pathways are activated during cold acclimation in addition to the CBF cold response pathway.
    Plant Cell, 2002. 14(8): p. 1675-90
    [PMID:12172015]
  3. Hudson ME,Lisch DR,Quail PH
    The FHY3 and FAR1 genes encode transposase-related proteins involved in regulation of gene expression by the phytochrome A-signaling pathway.
    Plant J., 2003. 34(4): p. 453-71
    [PMID:12753585]
  4. S
    ABA activates ADPR cyclase and cADPR induces a subset of ABA-responsive genes in Arabidopsis.
    Plant J., 2004. 38(3): p. 381-95
    [PMID:15086800]
  5. Tepperman JM, et al.
    Expression profiling of phyB mutant demonstrates substantial contribution of other phytochromes to red-light-regulated gene expression during seedling de-etiolation.
    Plant J., 2004. 38(5): p. 725-39
    [PMID:15144375]
  6. Vogel JT,Zarka DG,Van Buskirk HA,Fowler SG,Thomashow MF
    Roles of the CBF2 and ZAT12 transcription factors in configuring the low temperature transcriptome of Arabidopsis.
    Plant J., 2005. 41(2): p. 195-211
    [PMID:15634197]
  7. Stanley Kim H, et al.
    Transcriptional divergence of the duplicated oxidative stress-responsive genes in the Arabidopsis genome.
    Plant J., 2005. 41(2): p. 212-20
    [PMID:15634198]
  8. Kumagai T, et al.
    The common function of a novel subfamily of B-Box zinc finger proteins with reference to circadian-associated events in Arabidopsis thaliana.
    Biosci. Biotechnol. Biochem., 2008. 72(6): p. 1539-49
    [PMID:18540109]
  9. Ascencio-Ib
    Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.
    Plant Physiol., 2008. 148(1): p. 436-54
    [PMID:18650403]
  10. Datta S, et al.
    LZF1/SALT TOLERANCE HOMOLOG3, an Arabidopsis B-box protein involved in light-dependent development and gene expression, undergoes COP1-mediated ubiquitination.
    Plant Cell, 2008. 20(9): p. 2324-38
    [PMID:18796637]
  11. Khanna R, et al.
    The Arabidopsis B-box zinc finger family.
    Plant Cell, 2009. 21(11): p. 3416-20
    [PMID:19920209]
  12. Li G, et al.
    Coordinated transcriptional regulation underlying the circadian clock in Arabidopsis.
    Nat. Cell Biol., 2011. 13(5): p. 616-22
    [PMID:21499259]
  13. Arabidopsis Interactome Mapping Consortium
    Evidence for network evolution in an Arabidopsis interactome map.
    Science, 2011. 333(6042): p. 601-7
    [PMID:21798944]
  14. Yamawaki S,Yamashino T,Nakamichi N,Nakanishi H,Mizuno T
    Light-responsive double B-box containing transcription factors are conserved in Physcomitrella patens.
    Biosci. Biotechnol. Biochem., 2011. 75(10): p. 2037-41
    [PMID:21979077]
  15. Wang CQ,Guthrie C,Sarmast MK,Dehesh K
    BBX19 interacts with CONSTANS to repress FLOWERING LOCUS T transcription, defining a flowering time checkpoint in Arabidopsis.
    Plant Cell, 2014. 26(9): p. 3589-602
    [PMID:25228341]
  16. Wang CQ,Sarmast MK,Jiang J,Dehesh K
    The Transcriptional Regulator BBX19 Promotes Hypocotyl Growth by Facilitating COP1-Mediated EARLY FLOWERING3 Degradation in Arabidopsis.
    Plant Cell, 2015. 27(4): p. 1128-39
    [PMID:25841036]