PlantTFDB
Plant Transcription Factor Database
v5.0
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT4G33880.1
Common NameBHLH85, EN115, F17I5.70, RSL2
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 352aa    MW: 38770.4 Da    PI: 4.5879
Description ROOT HAIR DEFECTIVE 6-LIKE 2
Gene Model
Gene Model ID Type Source Coding Sequence
AT4G33880.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH31.92.4e-102823221055
                  HHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
          HLH  10 rrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                  r+RR+riN+++  L+ l+P+      +K++ +++Le+Av+Y+k Lq
  AT4G33880.1 282 RKRRERINERLRILQNLVPNG-----TKVDISTMLEEAVHYVKFLQ 322
                  9******************97.....8******************9 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088814.85272321IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474595.89E-14274338IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.104.8E-12277331IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003534.1E-11278327IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.44E-11281326No hitNo description
PfamPF000101.4E-7282322IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009733Biological Processresponse to auxin
GO:0016049Biological Processcell growth
GO:0045944Biological Processpositive regulation of transcription from RNA polymerase II promoter
GO:0048766Biological Processroot hair initiation
GO:0005634Cellular Componentnucleus
GO:0001046Molecular Functioncore promoter sequence-specific DNA binding
GO:0001228Molecular Functiontranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 352 aa     Download sequence    Send to blast
MEAMGEWSNN LGGMYTYATE EADFMNQLLA SYDHPGTGSS SGAAASGDHQ GLYWNLGSHH  60
NHLSLVSEAG SFCFSQESSS YSAGNSGYYT VVPPTVEENQ NETMDFGMED VTINTNSYLV  120
GEETSECDVE KYSSGKTLMP LETVVENHDD EESLLQSEIS VTTTKSLTGS KKRSRATSTD  180
KNKRARVNKR AQKNVEMSGD NNEGEEEEGE TKLKKRKNGA MMSRQNSSTT FCTEEESNCA  240
DQDGGGEDSS SKEDDPSKAL NLNGKTRASR GAATDPQSLY ARKRRERINE RLRILQNLVP  300
NGTKVDISTM LEEAVHYVKF LQLQIKLLSS DDLWMYAPIA FNGMDIGLSS PR
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.315420.0root
Expression -- Microarray ? help Back to Top
Source ID
Expression AtlasAT4G33880
AtGenExpressAT4G33880
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Roots. {ECO:0000269|PubMed:12679534}.
Functional Description ? help Back to Top
Source Description
TAIRRSL2 was expressed concurrently with RSL4 and its expression was controlled by RHD6 and RSL1. Required for root-hair growth.
Function -- GeneRIF ? help Back to Top
  1. Results suggest that OBF BINDING PROTEIN4 (OBP4)-mediated transcriptional repression of ROOT HAIR DEFECTIVE6-LIKE2 (RSL2) promoter to repress RSL2 contributes to the abscisic acid (ABA)-dependent inhibition of root hair growth.
    [PMID: 28167701]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT4G33880.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By jasmonic acid (JA) treatment. {ECO:0000269|PubMed:12679534}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT4G33880
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK2281100.0AK228110.1 Arabidopsis thaliana mRNA for putative bHLH transcription factor, complete cds, clone: RAFL14-58-P18.
GenBankBT0031370.0BT003137.1 Arabidopsis thaliana At4g33880 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_195114.20.0ROOT HAIR DEFECTIVE 6-LIKE 2
SwissprotQ84WK00.0BH085_ARATH; Transcription factor bHLH85
TrEMBLA0A178V2430.0A0A178V243_ARATH; RSL2
STRINGAT4G33880.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM28342663
Representative plantOGRP10481454
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  5. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  6. Czechowski T,Bari RP,Stitt M,Scheible WR,Udvardi MK
    Real-time RT-PCR profiling of over 1400 Arabidopsis transcription factors: unprecedented sensitivity reveals novel root- and shoot-specific genes.
    Plant J., 2004. 38(2): p. 366-79
    [PMID:15078338]
  7. Yi K,Menand B,Bell E,Dolan L
    A basic helix-loop-helix transcription factor controls cell growth and size in root hairs.
    Nat. Genet., 2010. 42(3): p. 264-7
    [PMID:20139979]
  8. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  9. Efroni I, et al.
    Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses.
    Dev. Cell, 2013. 24(4): p. 438-45
    [PMID:23449474]
  10. Rymen B, et al.
    ABA Suppresses Root Hair Growth via the OBP4 Transcriptional Regulator.
    Plant Physiol., 2017. 173(3): p. 1750-1762
    [PMID:28167701]
  11. Han H, et al.
    Altered expression of the TaRSL2 gene contributed to variation in root hair length during allopolyploid wheat evolution.
    Planta, 2017. 246(5): p. 1019-1028
    [PMID:28770336]