PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT4G30980.1
Common NameBHLH69, EN94, F6I18.110, LRL2
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 310aa    MW: 32879.7 Da    PI: 6.8451
Description LJRHL1-like 2
Gene Model
Gene Model ID Type Source Coding Sequence
AT4G30980.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH36.21.1e-11141186555
                  HHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
          HLH   5 hnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                  h+++Er RR+ri +++  L+el+P+ +      K +Ka++L + ++Y+k Lq
  AT4G30980.1 141 HSIAERLRRERIAERMKSLQELVPNgN------KTDKASMLDEIIDYVKFLQ 186
                  99***********************55......******************9 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF474596.54E-17134195IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000833.31E-13134190No hitNo description
PROSITE profilePS5088817.301136185IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.103.0E-16138195IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000105.5E-9141186IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003538.0E-14142191IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045944Biological Processpositive regulation of transcription from RNA polymerase II promoter
GO:0048767Biological Processroot hair elongation
GO:0005634Cellular Componentnucleus
GO:0001046Molecular Functioncore promoter sequence-specific DNA binding
GO:0001228Molecular Functiontranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000293anatomyguard cell
Sequence ? help Back to Top
Protein Sequence    Length: 310 aa     Download sequence    Send to blast
MNSSSLLTPS SSPSPHLQSP ATFDHDDFLH HIFSSTPWPS SVLDDTPPPT SDCAPVTGFH  60
HHDADSRNQI TMIPLSHNHP NDALFNGFST GSLPFHLPQG SGGQTQTQSQ ATASATTGGA  120
TAQPQTKPKV RARRGQATDP HSIAERLRRE RIAERMKSLQ ELVPNGNKTD KASMLDEIID  180
YVKFLQLQVK VLSMSRLGGA ASASSQISED AGGSHENTSS SGEAKMTEHQ VAKLMEEDMG  240
SAMQYLQGKG LCLMPISLAT TISTATCPSR SPFVKDTGVP LSPNLSTTIV ANGNGSSLVT  300
VKDAPSVSKP
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1145150RLRRER
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO1453502400.0
Expression AtlasAT4G30980-
AtGenExpressAT4G30980-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed constitutively in roots, leaves, stems, and flowers. {ECO:0000269|PubMed:12679534}.
Functional Description ? help Back to Top
Source Description
TAIREncodes a basic helix-loop-helix (bHLH) protein that regulates root hair development. One of the three Arabidopsis homologs of the Lotus japonicus ROOTHAIRLESS1 (LjRHL1) gene: At2g24260 (AtLRL1), At4g30980 (AtLRL2), and At5g58010 (AtLRL3).
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00462DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT4G30980.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by heat treatment. {ECO:0000269|PubMed:12679534}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT4G30980
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF4886010.0AF488601.1 Arabidopsis thaliana clone bHLH069 putative bHLH transcription factor mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001320095.10.0LJRHL1-like 2
RefseqNP_194827.30.0LJRHL1-like 2
SwissprotQ8S3D50.0BH069_ARATH; Transcription factor bHLH69
TrEMBLA0A1P8B7F00.0A0A1P8B7F0_ARATH; LJRHL1-like 2
TrEMBLA0A384LMW20.0A0A384LMW2_ARATH; LRL2
TrEMBLC0SVK80.0C0SVK8_ARATH; Uncharacterized protein At4g30980 (Fragment)
STRINGAT4G30980.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM30422763
Representative plantOGRP5816313
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Dal Bosco C, et al.
    Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana.
    J. Biol. Chem., 2004. 279(2): p. 1060-9
    [PMID:14576160]
  5. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  6. Maher C,Stein L,Ware D
    Evolution of Arabidopsis microRNA families through duplication events.
    Genome Res., 2006. 16(4): p. 510-9
    [PMID:16520461]
  7. Hanano S, et al.
    A systematic survey in Arabidopsis thaliana of transcription factors that modulate circadian parameters.
    BMC Genomics, 2008. 9: p. 182
    [PMID:18426557]
  8. Karas B, et al.
    Conservation of lotus and Arabidopsis basic helix-loop-helix proteins reveals new players in root hair development.
    Plant Physiol., 2009. 151(3): p. 1175-85
    [PMID:19675148]
  9. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  10. Hanada K, et al.
    Functional compensation of primary and secondary metabolites by duplicate genes in Arabidopsis thaliana.
    Mol. Biol. Evol., 2011. 28(1): p. 377-82
    [PMID:20736450]
  11. Lin Q, et al.
    GLABRA2 Directly Suppresses Basic Helix-Loop-Helix Transcription Factor Genes with Diverse Functions in Root Hair Development.
    Plant Cell, 2015. 27(10): p. 2894-906
    [PMID:26486447]
  12. Zhang J, et al.
    Sperm cells are passive cargo of the pollen tube in plant fertilization.
    Nat Plants, 2017. 3: p. 17079
    [PMID:28585562]