PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT4G28500.1
Common NameANAC073, F20O9.190, NAC073, SND2
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family NAC
Protein Properties Length: 305aa    MW: 33696.8 Da    PI: 9.2697
Description NAC domain containing protein 73
Gene Model
Gene Model ID Type Source Coding Sequence
AT4G28500.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM109.92.8e-34592001128
          NAM   1 lppGfrFhPtdeelvveyLkkkvegkk......lelee...vikev.diykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratk.......sg 81 
                  lp+G++F+Ptd+e++ e+L+ kv+++       ++  e   +i+   +i++++P++Lp  v+++ +  +fF++ +k+y+tg+rk+r+++       + 
  AT4G28500.1  59 LPAGVKFDPTDQEVL-EHLEGKVRDDAkklhplID--EfirTIDGEnGICYTHPEKLP-GVNKDGTVRHFFHRPSKAYTTGTRKRRKVHtdsdvggET 152
                  799**********99.99******99966654422..22223554445**********.677788899******************744345555578 PP

          NAM  82 yWkatgkdkevlskkgelvglkktLvfy..kgrapkgektdWvmheyrl 128
                  +W++tgk+++vl+ +g++ g kk+Lv+y   g+++k+ekt+Wvmh+y+l
  AT4G28500.1 153 RWHKTGKTRPVLA-GGRVRGYKKILVLYtnYGKQKKPEKTNWVMHQYHL 200
                  8************.9*************6658999************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019418.24E-3853219IPR003441NAC domain
PROSITE profilePS5100533.31659219IPR003441NAC domain
PfamPF023653.6E-1560200IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0007275Biological Processmulticellular organism development
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:2000652Biological Processregulation of secondary cell wall biogenesis
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000230anatomyinflorescence meristem
PO:0000272anatomyprotoxylem
PO:0000293anatomyguard cell
PO:0005352anatomyxylem
PO:0005848anatomysecondary xylem
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0025022anatomycollective leaf structure
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 305 aa     Download sequence    Send to blast
MTWCNDRSDV QTVERIIPSP GAAESPVASL PVSCHKTCPS CGHNFKFHEQ AGIHDLPGLP  60
AGVKFDPTDQ EVLEHLEGKV RDDAKKLHPL IDEFIRTIDG ENGICYTHPE KLPGVNKDGT  120
VRHFFHRPSK AYTTGTRKRR KVHTDSDVGG ETRWHKTGKT RPVLAGGRVR GYKKILVLYT  180
NYGKQKKPEK TNWVMHQYHL GTSEEEKEGE LVVSKVFYQT QPRQCGGSVA AAATAKDRPY  240
LHGLGGGGGR HLHYHLHHNN GNGKSNGSGG TAGAGEYYHN IPAIISFNQT GIQNHLVHDS  300
QPFIP
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO1453475920.0
Genevisible253798_at0.0
Expression AtlasAT4G28500-
AtGenExpressAT4G28500-
ATTED-IIAT4G28500-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in protoxylem and elongating interfascicular fiber cells of elongating internodes, developing metaxylem cells and interfascicular fibers of non-elongating internodes and developing secondary xylem of roots. {ECO:0000269|PubMed:18952777}.
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that plays a regulatory role in the development of secondary cell wall fibers (PubMed:18952777,PubMed:22133261). Involved in the regulation of cellulose and hemicellulose biosynthetic genes as well as of genes involved in lignin polymerization and signaling (PubMed:22133261). Is not a direct target of SND1 (PubMed:18952777). {ECO:0000269|PubMed:18952777, ECO:0000269|PubMed:22133261}.
Function -- GeneRIF ? help Back to Top
  1. SND2 regulates cellulose and hemicellulose biosynthetic genes in addition to those involved in lignin polymerization and signalling.
    [PMID: 22133261]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00459DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT4G28500.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Upstream Regulators) ? help Back to Top
Source Upstream Regulator (A: Activate/R: Repress)
ATRM AT1G32770 (A)
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT4G28500
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankDQ0566580.0DQ056658.1 Arabidopsis thaliana no apical meristem family protein (At4g28500) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_194579.10.0NAC domain containing protein 73
SwissprotO494590.0NAC73_ARATH; NAC domain-containing protein 73
TrEMBLA0A078HCI70.0A0A078HCI7_BRANA; BnaA01g08370D protein
STRINGAT4G28500.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP5251585
MalvidsOGEM20122881
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Ooka H, et al.
    Comprehensive analysis of NAC family genes in Oryza sativa and Arabidopsis thaliana.
    DNA Res., 2003. 10(6): p. 239-47
    [PMID:15029955]
  3. Zhao C,Craig JC,Petzold HE,Dickerman AW,Beers EP
    The xylem and phloem transcriptomes from secondary tissues of the Arabidopsis root-hypocotyl.
    Plant Physiol., 2005. 138(2): p. 803-18
    [PMID:15923329]
  4. Andersson-Gunner
    Biosynthesis of cellulose-enriched tension wood in Populus: global analysis of transcripts and metabolites identifies biochemical and developmental regulators in secondary wall biosynthesis.
    Plant J., 2006. 45(2): p. 144-65
    [PMID:16367961]
  5. Zhong R,Demura T,Ye ZH
    SND1, a NAC domain transcription factor, is a key regulator of secondary wall synthesis in fibers of Arabidopsis.
    Plant Cell, 2006. 18(11): p. 3158-70
    [PMID:17114348]
  6. Ko JH,Yang SH,Park AH,Lerouxel O,Han KH
    ANAC012, a member of the plant-specific NAC transcription factor family, negatively regulates xylary fiber development in Arabidopsis thaliana.
    Plant J., 2007. 50(6): p. 1035-48
    [PMID:17565617]
  7. Zhong R,Richardson EA,Ye ZH
    The MYB46 transcription factor is a direct target of SND1 and regulates secondary wall biosynthesis in Arabidopsis.
    Plant Cell, 2007. 19(9): p. 2776-92
    [PMID:17890373]
  8. Lasserre E,Jobet E,Llauro C,Delseny M
    AtERF38 (At2g35700), an AP2/ERF family transcription factor gene from Arabidopsis thaliana, is expressed in specific cell types of roots, stems and seeds that undergo suberization.
    Plant Physiol. Biochem., 2008. 46(12): p. 1051-61
    [PMID:18723362]
  9. Pogorelko GV,Fursova OV
    A highly efficient miPCR method for isolating FSTs from transgenic Arabidopsis thaliana plants.
    J. Genet., 2008. 87(2): p. 133-40
    [PMID:18776641]
  10. Zhong R,Lee C,Zhou J,McCarthy RL,Ye ZH
    A battery of transcription factors involved in the regulation of secondary cell wall biosynthesis in Arabidopsis.
    Plant Cell, 2008. 20(10): p. 2763-82
    [PMID:18952777]
  11. Grant EH,Fujino T,Beers EP,Brunner AM
    Characterization of NAC domain transcription factors implicated in control of vascular cell differentiation in Arabidopsis and Populus.
    Planta, 2010. 232(2): p. 337-52
    [PMID:20458494]
  12. Hanada K, et al.
    Functional compensation of primary and secondary metabolites by duplicate genes in Arabidopsis thaliana.
    Mol. Biol. Evol., 2011. 28(1): p. 377-82
    [PMID:20736450]
  13. Gaudinier A, et al.
    Enhanced Y1H assays for Arabidopsis.
    Nat. Methods, 2011. 8(12): p. 1053-5
    [PMID:22037706]
  14. Hussey SG, et al.
    SND2, a NAC transcription factor gene, regulates genes involved in secondary cell wall development in Arabidopsis fibres and increases fibre cell area in Eucalyptus.
    BMC Plant Biol., 2011. 11: p. 173
    [PMID:22133261]
  15. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]