PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT4G26150.1
Common NameCGA1, F20B18.260, GATA22, GNL
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family GATA
Protein Properties Length: 352aa    MW: 39345.3 Da    PI: 9.5931
Description cytokinin-responsive gata factor 1
Gene Model
Gene Model ID Type Source Coding Sequence
AT4G26150.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1GATA60.22.6e-19201234134
         GATA   1 CsnCgttkTplWRrgpdgnktLCnaCGlyyrkkg 34 
                  Cs C+ttkTplWR+gp+g+k+LCnaCG+++rk +
  AT4G26150.1 201 CSDCNTTKTPLWRSGPRGPKSLCNACGIRQRKAR 234
                  *******************************987 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM004014.1E-20195247IPR000679Zinc finger, GATA-type
SuperFamilySSF577161.95E-12198235No hitNo description
Gene3DG3DSA:3.30.50.102.8E-15199234IPR013088Zinc finger, NHR/GATA-type
CDDcd002022.11E-13200230No hitNo description
PROSITE profilePS5011412.44201231IPR000679Zinc finger, GATA-type
PfamPF003205.0E-17201234IPR000679Zinc finger, GATA-type
PROSITE patternPS003440201226IPR000679Zinc finger, GATA-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0007623Biological Processcircadian rhythm
GO:0009416Biological Processresponse to light stimulus
GO:0009735Biological Processresponse to cytokinin
GO:0009740Biological Processgibberellic acid mediated signaling pathway
GO:0009910Biological Processnegative regulation of flower development
GO:0010187Biological Processnegative regulation of seed germination
GO:0010380Biological Processregulation of chlorophyll biosynthetic process
GO:0010468Biological Processregulation of gene expression
GO:0030154Biological Processcell differentiation
GO:0045944Biological Processpositive regulation of transcription from RNA polymerase II promoter
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0000977Molecular FunctionRNA polymerase II regulatory region sequence-specific DNA binding
GO:0001085Molecular FunctionRNA polymerase II transcription factor binding
GO:0001228Molecular Functiontranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0003682Molecular Functionchromatin binding
GO:0008270Molecular Functionzinc ion binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000037anatomyshoot apex
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009025anatomyvascular leaf
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0025022anatomycollective leaf structure
PO:0001185developmental stageplant embryo globular stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 352 aa     Download sequence    Send to blast
MGSNFHYTID LNEDQNHQPF FASLGSSLHH HLQQQQQQQQ HFHHQASSNP SSLMSPSLSY  60
FPFLINSRQD QVYVGYNNNT FHDVLDTHIS QPLETKNFVS DGGSSSSDQM VPKKETRLKL  120
TIKKKDNHQD QTDLPQSPIK DMTGTNSLKW ISSKVRLMKK KKAIITTSDS SKQHTNNDQS  180
SNLSNSERQN GYNNDCVIRI CSDCNTTKTP LWRSGPRGPK SLCNACGIRQ RKARRAAMAT  240
ATATAVSGVS PPVMKKKMQN KNKISNGVYK ILSPLPLKVN TCKRMITLEE TALAEDLETQ  300
SNSTMLSSSD NIYFDDLALL LSKSSAYQQV FPQDEKEAAI LLMALSHGMV HG
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO306871270.0
Genevisible254016_at0.0
Expression AtlasAT4G26150-
AtGenExpressAT4G26150-
ATTED-IIAT4G26150-
Functional Description ? help Back to Top
Source Description
TAIREncodes a member of the GATA factor family of zinc finger transcription factors.
UniProtTranscriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. {ECO:0000250}.
Function -- GeneRIF ? help Back to Top
  1. CGA1 encodes a GATA factor, whose expression is rapidly induced by both the light and cytokinin signals in Arabidopsis thaliana.
    [PMID: 17587690]
  2. GNC and CGA1 regulate chlorophyll production, and positively regulate chloroplast growth in the hypocotyl.
    [PMID: 22811435]
  3. Constitutive Cga1 overexpression increases both chloroplast biogenesis and starch production but also results in delayed senescence and reduced grain filling. Cga1 regulates chloroplast development in higher plants.
    [PMID: 23548780]
  4. a cross-repressive interaction of GNC and GNL on the one side and SOC1 on the other in the control of flowering time, greening, and cold tolerance
    [PMID: 23739688]
  5. Data indicate that CARBON-METABOLISM INVOLVED (GNC) and GNC-LIKE (GNL)/CYTOKININ-RESPONSIVE GATA FACTOR1 (CGA1) expression is repressed by AUXIN RESPONSE FACTO ARF2 and ARF7.
    [PMID: 23878229]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT4G26150.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Upstream Regulators) ? help Back to Top
Source Upstream Regulator (A: Activate/R: Repress)
ATRM AT3G54340 (R), AT5G20240 (R)
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT1G57990(A), AT2G15890(A/R), AT2G29350(A), AT4G29130(R), AT4G30270(A), AT4G35770(A), AT5G26340(A/R)
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDcytokinin
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT4G26150
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankCP0026870.0CP002687.1 Arabidopsis thaliana chromosome 4 sequence.
GenBankAL1615640.0AL161564.2 Arabidopsis thaliana DNA chromosome 4, contig fragment No. 64.
GenBankAL0494830.0AL049483.1 Arabidopsis thaliana DNA chromosome 4, BAC clone F20B18 (ESSA project).
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_194345.10.0putative GATA transcription factor 22
SwissprotQ9SZI60.0GAT22_ARATH; Putative GATA transcription factor 22
TrEMBLD7MFC41e-175D7MFC4_ARALL; Zinc finger family protein
STRINGAT4G26150.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP6817287
MalvidsOGEM21092675
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Jeong MJ,Jeong MJ,Shih MC
    Interaction of a GATA factor with cis-acting elements involved in light regulation of nuclear genes encoding chloroplast glyceraldehyde-3-phosphate dehydrogenase in Arabidopsis.
    Biochem. Biophys. Res. Commun., 2003. 300(2): p. 555-62
    [PMID:12504119]
  3. Reyes JC,Muro-Pastor MI,Florencio FJ
    The GATA family of transcription factors in Arabidopsis and rice.
    Plant Physiol., 2004. 134(4): p. 1718-32
    [PMID:15084732]
  4. S
    ABA activates ADPR cyclase and cADPR induces a subset of ABA-responsive genes in Arabidopsis.
    Plant J., 2004. 38(3): p. 381-95
    [PMID:15086800]
  5. Wang R, et al.
    Genomic analysis of the nitrate response using a nitrate reductase-null mutant of Arabidopsis.
    Plant Physiol., 2004. 136(1): p. 2512-22
    [PMID:15333754]
  6. Scheible WR, et al.
    Genome-wide reprogramming of primary and secondary metabolism, protein synthesis, cellular growth processes, and the regulatory infrastructure of Arabidopsis in response to nitrogen.
    Plant Physiol., 2004. 136(1): p. 2483-99
    [PMID:15375205]
  7. Kiba T, et al.
    Combinatorial microarray analysis revealing arabidopsis genes implicated in cytokinin responses through the His->Asp Phosphorelay circuitry.
    Plant Cell Physiol., 2005. 46(2): p. 339-55
    [PMID:15695462]
  8. Brenner WG,Romanov GA,K
    Immediate-early and delayed cytokinin response genes of Arabidopsis thaliana identified by genome-wide expression profiling reveal novel cytokinin-sensitive processes and suggest cytokinin action through transcriptional cascades.
    Plant J., 2005. 44(2): p. 314-33
    [PMID:16212609]
  9. Bi YM, et al.
    Genetic analysis of Arabidopsis GATA transcription factor gene family reveals a nitrate-inducible member important for chlorophyll synthesis and glucose sensitivity.
    Plant J., 2005. 44(4): p. 680-92
    [PMID:16262716]
  10. Che P,Lall S,Nettleton D,Howell SH
    Gene expression programs during shoot, root, and callus development in Arabidopsis tissue culture.
    Plant Physiol., 2006. 141(2): p. 620-37
    [PMID:16648215]
  11. Nemhauser JL,Hong F,Chory J
    Different plant hormones regulate similar processes through largely nonoverlapping transcriptional responses.
    Cell, 2006. 126(3): p. 467-75
    [PMID:16901781]
  12. Lee DJ, et al.
    Genome-wide expression profiling of ARABIDOPSIS RESPONSE REGULATOR 7(ARR7) overexpression in cytokinin response.
    Mol. Genet. Genomics, 2007. 277(2): p. 115-37
    [PMID:17061125]
  13. Manfield IW,Devlin PF,Jen CH,Westhead DR,Gilmartin PM
    Conservation, convergence, and divergence of light-responsive, circadian-regulated, and tissue-specific expression patterns during evolution of the Arabidopsis GATA gene family.
    Plant Physiol., 2007. 143(2): p. 941-58
    [PMID:17208962]
  14. Osuna D, et al.
    Temporal responses of transcripts, enzyme activities and metabolites after adding sucrose to carbon-deprived Arabidopsis seedlings.
    Plant J., 2007. 49(3): p. 463-91
    [PMID:17217462]
  15. Kleine T,Kindgren P,Benedict C,Hendrickson L,Strand A
    Genome-wide gene expression analysis reveals a critical role for CRYPTOCHROME1 in the response of Arabidopsis to high irradiance.
    Plant Physiol., 2007. 144(3): p. 1391-406
    [PMID:17478635]
  16. Naito T,Kiba T,Koizumi N,Yamashino T,Mizuno T
    Characterization of a unique GATA family gene that responds to both light and cytokinin in Arabidopsis thaliana.
    Biosci. Biotechnol. Biochem., 2007. 71(6): p. 1557-60
    [PMID:17587690]
  17. Chevalier F, et al.
    GeBP and GeBP-like proteins are noncanonical leucine-zipper transcription factors that regulate cytokinin response in Arabidopsis.
    Plant Physiol., 2008. 146(3): p. 1142-54
    [PMID:18162594]
  18. Mara CD,Irish VF
    Two GATA transcription factors are downstream effectors of floral homeotic gene action in Arabidopsis.
    Plant Physiol., 2008. 147(2): p. 707-18
    [PMID:18417639]
  19. Richter R,Behringer C,M
    The GATA-type transcription factors GNC and GNL/CGA1 repress gibberellin signaling downstream from DELLA proteins and PHYTOCHROME-INTERACTING FACTORS.
    Genes Dev., 2010. 24(18): p. 2093-104
    [PMID:20844019]
  20. K
    Ectopic expression of different cytokinin-regulated transcription factor genes of Arabidopsis thaliana alters plant growth and development.
    J. Plant Physiol., 2011. 168(12): p. 1320-7
    [PMID:21453984]
  21. Hudson D, et al.
    GNC and CGA1 modulate chlorophyll biosynthesis and glutamate synthase (GLU1/Fd-GOGAT) expression in Arabidopsis.
    PLoS ONE, 2011. 6(11): p. e26765
    [PMID:22102866]
  22. Chiang YH, et al.
    Functional characterization of the GATA transcription factors GNC and CGA1 reveals their key role in chloroplast development, growth, and division in Arabidopsis.
    Plant Physiol., 2012. 160(1): p. 332-48
    [PMID:22811435]
  23. Zhang X, et al.
    Transcription repressor HANABA TARANU controls flower development by integrating the actions of multiple hormones, floral organ specification genes, and GATA3 family genes in Arabidopsis.
    Plant Cell, 2013. 25(1): p. 83-101
    [PMID:23335616]
  24. Hudson D, et al.
    Rice cytokinin GATA transcription Factor1 regulates chloroplast development and plant architecture.
    Plant Physiol., 2013. 162(1): p. 132-44
    [PMID:23548780]
  25. Richter R,Bastakis E,Schwechheimer C
    Cross-repressive interactions between SOC1 and the GATAs GNC and GNL/CGA1 in the control of greening, cold tolerance, and flowering time in Arabidopsis.
    Plant Physiol., 2013. 162(4): p. 1992-2004
    [PMID:23739688]
  26. Richter R,Behringer C,Zourelidou M,Schwechheimer C
    Convergence of auxin and gibberellin signaling on the regulation of the GATA transcription factors GNC and GNL in Arabidopsis thaliana.
    Proc. Natl. Acad. Sci. U.S.A., 2013. 110(32): p. 13192-7
    [PMID:23878229]
  27. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]