PlantRegMap
Plant Transcription Factor Database
PlantTFDB
v5.0
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT4G06634.3
Common NameAtYY1, YY1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family C2H2
Protein Properties Length: 380aa    MW: 44014.6 Da    PI: 6.2074
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT4G06634.3genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H210.80.00167092323
                 ET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2  3 Cp..dCgksFsrksnLkrHirtH 23
                 C+   Cgk+F + s L++H   H
  AT4G06634.3 70 CSydGCGKTFFDVSALRKHSHIH 92
                 78889**************7766 PP

2zf-C2H2171.6e-0597121123
                  EEET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                  y+C    Cgk F ++s LkrH   H
  AT4G06634.3  97 YVCDqeGCGKKFLDSSKLKRHYLIH 121
                  99*******************9988 PP

3zf-C2H211.60.00084127155123
                  EEET..TTT....EEESSHHHHHHHHHHT CS
      zf-C2H2   1 ykCp..dCg....ksFsrksnLkrHirtH 23 
                  y C+   Cg    + Fs   nL++H++tH
  AT4G06634.3 127 YICTyeGCGklwmQAFSLDFNLRSHMKTH 155
                  8899999*********************9 PP

4zf-C2H2130.00032223248123
                  EEET..TTTEEESSHHHHHHHHHH.T CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                  y Cp   C k + + + Lk H+++ H
  AT4G06634.3 223 YACPyeGCEKAYIHEYKLKLHLKReH 248
                  89*********************999 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.603.7E-146394IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576672.23E-56393No hitNo description
SMARTSM003550.00536892IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.9496897IPR007087Zinc finger, C2H2
PROSITE patternPS0002807092IPR007087Zinc finger, C2H2
SuperFamilySSF576671.69E-1184135No hitNo description
Gene3DG3DSA:3.30.160.604.8E-1495119IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.001197121IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015714.27497126IPR007087Zinc finger, C2H2
PROSITE patternPS00028099121IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.603.3E-18120152IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003551127155IPR015880Zinc finger, C2H2-like
SuperFamilySSF576675.03E-7141187No hitNo description
Gene3DG3DSA:3.30.160.604.6E-9153183IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.12161186IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280163186IPR007087Zinc finger, C2H2
SuperFamilySSF576671.31E-5218246No hitNo description
Gene3DG3DSA:3.30.160.606.6E-9219245IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.012223248IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.328223253IPR007087Zinc finger, C2H2
PROSITE patternPS000280225248IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000293anatomyguard cell
Sequence ? help Back to Top
Protein Sequence    Length: 380 aa     Download sequence    Send to blast
MDHQNYQYQN PFERRPILKS KAPAVKWIKE WVPQDIVATE DTFSRLKEKE KEPDVPEPEP  60
EPTTEILFLC SYDGCGKTFF DVSALRKHSH IHGERQYVCD QEGCGKKFLD SSKLKRHYLI  120
HTGERNYICT YEGCGKLWMQ AFSLDFNLRS HMKTHSQENY HICPYSGCVK RYAHEYKLKN  180
HVAAYHEKNG GGETPKYTPP AEKVLRTVKT PATVCGPSSD RPYACPYEGC EKAYIHEYKL  240
KLHLKREHPG HLQEENADTP TLNKHNGNDR NEIDDGSDQD VYRKHASNGK GQTHKQQSRA  300
KPNMRTPPAK VGKKGSTSSP AKARIAKKPW QAKETFEEVE REEEEDSEET EEDRDNVEDG  360
WRFGENNEDD DDDEETEYED
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C9e-35701858117PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.472640.0inflorescence| silique
Expression -- Microarray ? help Back to Top
Source ID
Expression AtlasAT4G06634
AtGenExpressAT4G06634
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Rapidly induced following seed germination, especially in tender cotyledons. {ECO:0000269|PubMed:26961720}.
UniprotTISSUE SPECIFICITY: Mostly expressed in flowers, to a lower extent in seedlings, stems and leaves, and, at low levels, in roots and senescent leaves. {ECO:0000269|PubMed:26961720}.
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Function -- GeneRIF ? help Back to Top
  1. genome-wide target gene analysis revealed that AtYY1 was involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism, and stress response[AtYY1]
    [PMID: 22508367]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT4G06634.3
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT4G06634
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0731620.0AB073162.1 Arabidopsis thaliana DNA, chromosome 4 centromere region, BAC clone:F8H12.
GenBankCP0026870.0CP002687.1 Arabidopsis thaliana chromosome 4 sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001190684.10.0zinc finger (C2H2 type) family protein
SwissprotQ2V3L30.0YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLF4JGT70.0F4JGT7_ARATH; Zinc finger (C2H2 type) family protein
STRINGAT4G06634.10.0(Arabidopsis thaliana)
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Reiland S, et al.
    Large-scale Arabidopsis phosphoproteome profiling reveals novel chloroplast kinase substrates and phosphorylation networks.
    Plant Physiol., 2009. 150(2): p. 889-903
    [PMID:19376835]
  3. Rehrauer H, et al.
    AGRONOMICS1: a new resource for Arabidopsis transcriptome profiling.
    Plant Physiol., 2010. 152(2): p. 487-99
    [PMID:20032078]
  4. Wu X,Cheng Y,Li T,Wang Z,Liu JY
    In vitro identification of DNA-binding motif for the new zinc finger protein AtYY1.
    Acta Biochim. Biophys. Sin. (Shanghai), 2012. 44(6): p. 483-9
    [PMID:22508367]
  5. Lai Z, et al.
    MED18 interaction with distinct transcription factors regulates multiple plant functions.
    Nat Commun, 2014. 5: p. 3064
    [PMID:24451981]
  6. Bieluszewski T, et al.
    AtEAF1 is a potential platform protein for Arabidopsis NuA4 acetyltransferase complex.
    BMC Plant Biol., 2015. 15: p. 75
    [PMID:25849764]
  7. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  8. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]