PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT4G04450.1
Common NameAtWRKY42, T26N6.6, WRKY42
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family WRKY
Protein Properties Length: 528aa    MW: 58071.5 Da    PI: 7.0877
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT4G04450.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY97.87.2e-31292350259
                  --SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS
         WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 
                  +Dg++WrKYGqK+ kg+++pr+YYrCt+a gCpv+k+v+r+aed +++++tYeg+Hnh+
  AT4G04450.1 292 SDGCQWRKYGQKMAKGNPCPRAYYRCTMAvGCPVRKQVQRCAEDRTILITTYEGNHNHP 350
                  7*********************************************************7 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.809.7E-34276352IPR003657WRKY domain
SuperFamilySSF1182907.59E-28284352IPR003657WRKY domain
PROSITE profilePS5081129.838286352IPR003657WRKY domain
SMARTSM007742.6E-37291351IPR003657WRKY domain
PfamPF031061.7E-26293350IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000293anatomyguard cell
PO:0009046anatomyflower
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 528 aa     Download sequence    Send to blast
MFRFPVSLGG GPRENLKPSD EQHQRAVVNE VDFFRSAEKR DRVSREEQNI IADETHRVHV  60
KRENSRVDDH DDRSTDHINI GLNLLTANTG SDESMVDDGL SVDMEEKRTK CENAQLREEL  120
KKASEDNQRL KQMLSQTTNN FNSLQMQLVA VMRQQEDHHH LATTENNDNV KNRHEVPEMV  180
PRQFIDLGPH SDEVSSEERT TVRSGSPPSL LEKSSSRQNG KRVLVREESP ETESNGWRNP  240
NKVPKHHASS SICGGNGSEN ASSKVIEQAA AEATMRKARV SVRARSEAPM LSDGCQWRKY  300
GQKMAKGNPC PRAYYRCTMA VGCPVRKQVQ RCAEDRTILI TTYEGNHNHP LPPAAMNMAS  360
TTTAAASMLL SGSTMSNQDG LMNPTNLLAR TILPCSSSMA TISASAPFPT ITLDLTESPN  420
GNNPTNNPLM QFSQRSGLVE LNQSVLPHMM GQALYYNQQS KFSGLHMPSQ PLNAGESVSA  480
ATAAIASNPN FAAALAAAIT SIINGSNNQQ NGNNNNSNVT TSNVDNRQ
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ayd_A3e-22278354176WRKY transcription factor 1
Search in ModeBase
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO1865115240.0
Genevisible255337_at0.0
Expression AtlasAT4G04450-
AtGenExpressAT4G04450-
ATTED-IIAT4G04450-
Functional Description ? help Back to Top
Source Description
TAIRmember of WRKY Transcription Factor; Group II-b
UniProtTranscription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Modulates phosphate homeostasis and Pi translocation by regulating PHO1 expression (PubMed:25733771). {ECO:0000250, ECO:0000269|PubMed:25733771}.
Function -- GeneRIF ? help Back to Top
  1. AtWRKY42 modulated Pi homeostasis by regulating the expression of PHO1 and PHT1;1 to adapt to environmental changes in inorganic phosphate (Pi) availability.
    [PMID: 25733771]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00428DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT4G04450.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Upstream Regulators) ? help Back to Top
Source Upstream Regulator (A: Activate/R: Repress)
ATRM AT1G62300 (R)
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT3G23430(R)
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT4G04450
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY0526500.0AY052650.1 Arabidopsis thaliana WRKY transcription factor 42 (WRKY42) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_192354.10.0putative WRKY transcription factor 42
SwissprotQ9XEC30.0WRK42_ARATH; Probable WRKY transcription factor 42
TrEMBLQ1PEB90.0Q1PEB9_ARATH; Putative uncharacterized protein At4g04450
STRINGAT4G04450.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP1417875
MalvidsOGEM105728107
Publications ? help Back to Top
  1. Eulgem T,Rushton PJ,Robatzek S,Somssich IE
    The WRKY superfamily of plant transcription factors.
    Trends Plant Sci., 2000. 5(5): p. 199-206
    [PMID:10785665]
  2. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  3. Asai T, et al.
    MAP kinase signalling cascade in Arabidopsis innate immunity.
    Nature, 2002. 415(6875): p. 977-83
    [PMID:11875555]
  4. Robatzek S,Somssich IE
    Targets of AtWRKY6 regulation during plant senescence and pathogen defense.
    Genes Dev., 2002. 16(9): p. 1139-49
    [PMID:12000796]
  5. Zou X,Seemann JR,Neuman D,Shen QJ
    A WRKY gene from creosote bush encodes an activator of the abscisic acid signaling pathway.
    J. Biol. Chem., 2004. 279(53): p. 55770-9
    [PMID:15504732]
  6. Miao Y,Laun T,Zimmermann P,Zentgraf U
    Targets of the WRKY53 transcription factor and its role during leaf senescence in Arabidopsis.
    Plant Mol. Biol., 2004. 55(6): p. 853-67
    [PMID:15604721]
  7. Manzano C,Abraham Z,L
    Identification of ubiquitinated proteins in Arabidopsis.
    Plant Mol. Biol., 2008. 68(1-2): p. 145-58
    [PMID:18535787]
  8. Chen YF, et al.
    The WRKY6 transcription factor modulates PHOSPHATE1 expression in response to low Pi stress in Arabidopsis.
    Plant Cell, 2009. 21(11): p. 3554-66
    [PMID:19934380]
  9. Su T, et al.
    WRKY42 modulates phosphate homeostasis through regulating phosphate translocation and acquisition in Arabidopsis.
    Plant Physiol., 2015. 167(4): p. 1579-91
    [PMID:25733771]
  10. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]