PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT4G01120.1
Common NameATBZIP54, BZIP54, F2N1.12, GBF2
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bZIP
Protein Properties Length: 360aa    MW: 38788.7 Da    PI: 9.1746
Description G-box binding factor 2
Gene Model
Gene Model ID Type Source Coding Sequence
AT4G01120.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1bZIP_171.41.3e-22247310164
                  XXXXCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC CS
       bZIP_1   1 ekelkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkevaklkseve 64 
                  eke+kre+rkq+NRe+ArrsR+RK+ae+e+L  kv++L aeN++L+++l +l++e++kl+ e+e
  AT4G01120.1 247 EKEVKREKRKQSNRESARRSRLRKQAETEQLSVKVDALVAENMSLRSKLGQLNNESEKLRLENE 310
                  89*********************************************************99885 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF077776.4E-30195IPR012900G-box binding protein, multifunctional mosaic region
PfamPF165962.9E-14129229No hitNo description
Gene3DG3DSA:1.20.5.1704.2E-17242306No hitNo description
SMARTSM003384.0E-20247311IPR004827Basic-leucine zipper domain
PfamPF001703.7E-21247309IPR004827Basic-leucine zipper domain
PROSITE profilePS5021712.53249312IPR004827Basic-leucine zipper domain
SuperFamilySSF579592.56E-10250306No hitNo description
CDDcd147023.18E-20252301No hitNo description
PROSITE patternPS000360254269IPR004827Basic-leucine zipper domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009637Biological Processresponse to blue light
GO:0005634Cellular Componentnucleus
GO:0005737Cellular Componentcytoplasm
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000084anatomyplant sperm cell
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025195anatomypollen tube cell
PO:0025281anatomypollen
PO:0001017developmental stageM germinated pollen stage
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 360 aa     Download sequence    Send to blast
MGSNEEGNPT NNSDKPSQAA APEQSNVHVY HHDWAAMQAY YGPRVGIPQY YNSNLAPGHA  60
PPPYMWASPS PMMAPYGAPY PPFCPPGGVY AHPGVQMGSQ PQGPVSQSAS GVTTPLTIDA  120
PANSAGNSDH GFMKKLKEFD GLAMSISNNK VGSAEHSSSE HRSSQSSEND GSSNGSDGNT  180
TGGEQSRRKR RQQRSPSTGE RPSSQNSLPL RGENEKPDVT MGTPVMPTAM SFQNSAGMNG  240
VPQPWNEKEV KREKRKQSNR ESARRSRLRK QAETEQLSVK VDALVAENMS LRSKLGQLNN  300
ESEKLRLENE AILDQLKAQA TGKTENLISR VDKNNSVSGS KTVQHQLLNA SPITDPVAAS
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1263269RRSRLRK
2263270RRSRLRKQ
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.230010.0leaf| root| silique| vegetative tissue
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO306788170.0
Genevisible255625_at0.0
Expression AtlasAT4G01120-
AtGenExpressAT4G01120-
ATTED-IIAT4G01120-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Found in both light and dark grown leaves. {ECO:0000269|PubMed:1373374}.
Functional Description ? help Back to Top
Source Description
TAIRbZIP (basic leucine zipper) transcription factor that binds to the G-box regulatory element found in many plant promoters. GBF2 nuclear localization is increased by blue light
UniProtBinds to the G-box motif (5'-CCACGTGG-3') of the rbcS-1A gene promoter. G-box and G-box-like motifs are cis-acting elements defined in promoters of certain plant genes which are regulated by such diverse stimuli as light-induction or hormone control. GBF2 is found to bind asymmetrically to the G-box. {ECO:0000269|PubMed:1373374}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT4G01120.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Interaction ? help Back to Top
Source Intact With
BioGRIDAT5G11260, AT1G03970
IntActSearch P42775
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT4G01120
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY0626670.0AY062667.1 Arabidopsis thaliana Unknown protein (GBF2) mRNA, complete cds.
GenBankAY0933160.0AY093316.1 Arabidopsis thaliana unknown protein (GBF2) mRNA, complete cds.
GenBankX638950.0X63895.1 A.thaliana mRNA GBF2 for G-box binding factor 2.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_192021.10.0G-box binding factor 2
SwissprotP427750.0GBF2_ARATH; G-box-binding factor 2
TrEMBLQ8LE350.0Q8LE35_ARATH; GBF2, G-box binding factor
STRINGAT4G01120.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM35712661
Representative plantOGRP43461123
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Jakoby M, et al.
    bZIP transcription factors in Arabidopsis.
    Trends Plant Sci., 2002. 7(3): p. 106-11
    [PMID:11906833]
  3. Schindler U,Menkens AE,Beckmann H,Ecker JR,Cashmore AR
    Heterodimerization between light-regulated and ubiquitously expressed Arabidopsis GBF bZIP proteins.
    EMBO J., 1992. 11(4): p. 1261-73
    [PMID:1373374]
  4. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  5. Jiao Y, et al.
    A genome-wide analysis of blue-light regulation of Arabidopsis transcription factor gene expression during seedling development.
    Plant Physiol., 2003. 133(4): p. 1480-93
    [PMID:14605227]
  6. Leonhardt N, et al.
    Microarray expression analyses of Arabidopsis guard cells and isolation of a recessive abscisic acid hypersensitive protein phosphatase 2C mutant.
    Plant Cell, 2004. 16(3): p. 596-615
    [PMID:14973164]
  7. Rizhsky L, et al.
    When defense pathways collide. The response of Arabidopsis to a combination of drought and heat stress.
    Plant Physiol., 2004. 134(4): p. 1683-96
    [PMID:15047901]
  8. Deppmann CD, et al.
    Dimerization specificity of all 67 B-ZIP motifs in Arabidopsis thaliana: a comparison to Homo sapiens B-ZIP motifs.
    Nucleic Acids Res., 2004. 32(11): p. 3435-45
    [PMID:15226410]
  9. Lee BH,Henderson DA,Zhu JK
    The Arabidopsis cold-responsive transcriptome and its regulation by ICE1.
    Plant Cell, 2005. 17(11): p. 3155-75
    [PMID:16214899]
  10. Fujita Y, et al.
    AREB1 Is a transcription activator of novel ABRE-dependent ABA signaling that enhances drought stress tolerance in Arabidopsis.
    Plant Cell, 2005. 17(12): p. 3470-88
    [PMID:16284313]
  11. Deppmann CD,Alvania RS,Taparowsky EJ
    Cross-species annotation of basic leucine zipper factor interactions: Insight into the evolution of closed interaction networks.
    Mol. Biol. Evol., 2006. 23(8): p. 1480-92
    [PMID:16731568]
  12. Cheng C, et al.
    An early response regulatory cluster induced by low temperature and hydrogen peroxide in seedlings of chilling-tolerant japonica rice.
    BMC Genomics, 2007. 8: p. 175
    [PMID:17577400]
  13. Chawade A,Br
    Putative cold acclimation pathways in Arabidopsis thaliana identified by a combined analysis of mRNA co-expression patterns, promoter motifs and transcription factors.
    BMC Genomics, 2007. 8: p. 304
    [PMID:17764576]
  14. Shen H,Cao K,Wang X
    AtbZIP16 and AtbZIP68, two new members of GBFs, can interact with other G group bZIPs in Arabidopsis thaliana.
    BMB Rep, 2008. 41(2): p. 132-8
    [PMID:18315949]
  15. Wang Y, et al.
    Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.
    Plant Physiol., 2008. 148(3): p. 1201-11
    [PMID:18775970]
  16. Gong W, et al.
    The development of protein microarrays and their applications in DNA-protein and protein-protein interaction analyses of Arabidopsis transcription factors.
    Mol Plant, 2008. 1(1): p. 27-41
    [PMID:19802365]
  17. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  18. Li B, et al.
    Promoter-based integration in plant defense regulation.
    Plant Physiol., 2014. 166(4): p. 1803-20
    [PMID:25352272]
  19. Song L, et al.
    A transcription factor hierarchy defines an environmental stress response network.
    Science, 2017.
    [PMID:27811239]
  20. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  21. Menkens AE,Cashmore AR
    Isolation and characterization of a fourth Arabidopsis thaliana G-box-binding factor, which has similarities to Fos oncoprotein.
    Proc. Natl. Acad. Sci. U.S.A., 1994. 91(7): p. 2522-6
    [PMID:8146148]
  22. Terzaghi WB,Bertekap RL,Cashmore AR
    Intracellular localization of GBF proteins and blue light-induced import of GBF2 fusion proteins into the nucleus of cultured Arabidopsis and soybean cells.
    Plant J., 1997. 11(5): p. 967-82
    [PMID:9193069]