PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT4G00870.1
Common NameA_TM018A10.7, BHLH14, EN33, T18A10.17
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 423aa    MW: 47732.7 Da    PI: 7.7291
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT4G00870.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH39.79e-13249294454
                  HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
          HLH   4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                  +h e+E++RR+++N++f  Lr ++Pk       +++Ka+ L  Av YI sL
  AT4G00870.1 249 SHVEAEKQRREKLNHRFYALRAIVPKV-----SRMDKASLLSDAVSYIESL 294
                  799***********************6.....4****************99 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142153.6E-3035189IPR025610Transcription factor MYC/MYB N-terminal
SuperFamilySSF474591.24E-16244309IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088816.475245294IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.84E-11248298No hitNo description
PfamPF000102.1E-10249294IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.102.8E-16249310IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003539.1E-15251300IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000037anatomyshoot apex
PO:0000293anatomyguard cell
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009052anatomyflower pedicel
PO:0025022anatomycollective leaf structure
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 423 aa     Download sequence    Send to blast
MYNLTFSPSL SSSLLSFTQQ TPAAIVSSSP PDLVLQQKLR FVVETSPDRW AYVIFWQKMF  60
DDQSDRSYLV WVDGHFCGNK NNNSQENYTT NSIECELMMD GGDDLELFYA ASFYGEDRSP  120
RKEVSDESLV WLTGPDELRF SNYERAKEAG FHGVHTLVSI PINNGIIELG SSESIIQNRN  180
FINRVKSIFG SGKTTKHTNQ TGSYPKPAVS DHSKSGNQQF GSERKRRRKL ETTRVAAATK  240
EKHHPAVLSH VEAEKQRREK LNHRFYALRA IVPKVSRMDK ASLLSDAVSY IESLKSKIDD  300
LETEIKKMKM TETDKLDNSS SNTSPSSVEY QVNQKPSKSN RGSDLEVQVK IVGEEAIIRV  360
QTENVNHPTS ALMSALMEMD CRVQHANASR LSQVMVQDVV VLVPEGLRSE DRLRTTLVRT  420
LSL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A1e-20248304763Transcription factor MYC2
5gnj_B1e-20248304763Transcription factor MYC2
5gnj_E1e-20248304763Transcription factor MYC2
5gnj_F1e-20248304763Transcription factor MYC2
5gnj_G1e-20248304763Transcription factor MYC2
5gnj_I1e-20248304763Transcription factor MYC2
5gnj_M1e-20248304763Transcription factor MYC2
5gnj_N1e-20248304763Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1222229ERKRRRKL
2223227RKRRR
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.345060.0flower
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible255644_at0.0
Expression AtlasAT4G00870-
AtGenExpressAT4G00870-
ATTED-IIAT4G00870-
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT4G00870.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT4G00870
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAJ5198120.0AJ519812.1 Arabidopsis thaliana mRNA for putative bHLH transcription factor.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_567195.10.0basic helix-loop-helix (bHLH) DNA-binding superfamily protein
SwissprotO230900.0BH014_ARATH; Transcription factor bHLH14
TrEMBLA0A178V3J70.0A0A178V3J7_ARATH; Uncharacterized protein
STRINGAT4G00870.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM30392163
Representative plantOGRP8004717
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Dal Bosco C, et al.
    Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana.
    J. Biol. Chem., 2004. 279(2): p. 1060-9
    [PMID:14576160]
  5. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  6. Hu W,Wang Y,Bowers C,Ma H
    Isolation, sequence analysis, and expression studies of florally expressed cDNAs in Arabidopsis.
    Plant Mol. Biol., 2003. 53(4): p. 545-63
    [PMID:15010618]
  7. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  8. Elrouby N,Coupland G
    Proteome-wide screens for small ubiquitin-like modifier (SUMO) substrates identify Arabidopsis proteins implicated in diverse biological processes.
    Proc. Natl. Acad. Sci. U.S.A., 2010. 107(40): p. 17415-20
    [PMID:20855607]
  9. Tominaga-Wada R,Iwata M,Nukumizu Y,Wada T
    Analysis of IIId, IIIe and IVa group basic-helix-loop-helix proteins expressed in Arabidopsis root epidermis.
    Plant Sci., 2011. 181(4): p. 471-8
    [PMID:21889054]
  10. Kundu N,Dozier U,Deslandes L,Somssich IE,Ullah H
    Arabidopsis scaffold protein RACK1A interacts with diverse environmental stress and photosynthesis related proteins.
    Plant Signal Behav, 2013. 8(5): p. e24012
    [PMID:23435172]
  11. Efroni I, et al.
    Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses.
    Dev. Cell, 2013. 24(4): p. 438-45
    [PMID:23449474]
  12. Song S, et al.
    The bHLH subgroup IIId factors negatively regulate jasmonate-mediated plant defense and development.
    PLoS Genet., 2013. 9(7): p. e1003653
    [PMID:23935516]
  13. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  14. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]