PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT3G57800.1
Common NameBHLH60, EN91, F15B8.10, T10K17.10
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 426aa    MW: 46575.5 Da    PI: 6.2949
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT3G57800.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH222.9e-07214240430
                  HHHHHHHHHHHHHHHHHHHHHCTSCCC CS
          HLH   4 ahnerErrRRdriNsafeeLrellPka 30 
                  +h+ +Er RR++iN ++  L+el+P +
  AT3G57800.1 214 SHSLAERARREKINARMKLLQELVPGC 240
                  8************************86 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF474599.99E-12208240IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.20E-5208244No hitNo description
PROSITE profilePS5088812.328210307IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.103.2E-12214240IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000108.4E-5214240IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003539.6E-5216313IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.103.2E-12287325IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474599.99E-12288326IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 426 aa     Download sequence    Send to blast
MDLTGGFGAR SGGVGPCREP IGLESLHLGD EFRQLVTTLP PENPGGSFTA LLELPPTQAV  60
ELLHFTDSSS SQQAAVTGIG GEIPPPLHSF GGTLAFPSNS VLMERAARFS VIATEQQNGN  120
ISGETPTSSV PSNSSANLDR VKTEPAETDS SQRLISDSAI ENQIPCPNQN NRNGKRKDFE  180
KKGKSSTKKN KSSEENEKLP YVHVRARRGQ ATDSHSLAER ARREKINARM KLLQELVPGC  240
DKGTDFGGKI KIKVCFGVHL LMISGKKVAI FLWKVSCEDL IDCSFSPPRI QGTALVLDEI  300
INHVQSLQRQ VEMLSMRLAA VNPRIDFNLD TILASENGSL MDGSFNAAPM QLAWPQQAIE  360
TEQSFHHRQL QQPPTQQWPF DGLNQPVWGR EEDQAHGNDN SNLMAVSENV MVASANLHPN  420
QVKMEL
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.347970.0floral meristem| flower
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO306958310.0
Genevisible251601_at1e-133
Expression AtlasAT3G57800-
AtGenExpressAT3G57800-
ATTED-IIAT3G57800-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed constitutively in roots, leaves, stems, and flowers. {ECO:0000269|PubMed:12679534}.
Function -- GeneRIF ? help Back to Top
  1. bHLH48 and bHLH60 positively regulate gibberellin-mediated flowering
    [PMID: 28591805]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT3G57800.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Interaction ? help Back to Top
Source Intact With
BioGRIDAT5G63090
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT3G57800
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF4885930.0AF488593.1 Arabidopsis thaliana clone bHLH060 putative bHLH transcription factor mRNA, complete cds.
GenBankAY1397730.0AY139773.1 Arabidopsis thaliana AT3g57800/T10K17_10 mRNA, complete cds.
GenBankBT0030370.0BT003037.1 Arabidopsis thaliana AT3g57800/T10K17_10 gene, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_567057.20.0basic helix-loop-helix (bHLH) DNA-binding superfamily protein
SwissprotQ3EAI10.0BH060_ARATH; Transcription factor bHLH60
TrEMBLA0A178VB920.0A0A178VB92_ARATH; Uncharacterized protein
STRINGAT3G57800.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM25762771
Representative plantOGRP5816313
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  5. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  6. Husbands A,Bell EM,Shuai B,Smith HM,Springer PS
    LATERAL ORGAN BOUNDARIES defines a new family of DNA-binding transcription factors and can interact with specific bHLH proteins.
    Nucleic Acids Res., 2007. 35(19): p. 6663-71
    [PMID:17913740]
  7. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  8. Li Y,Wang H,Li X,Liang G,Yu D
    Two DELLA-interacting proteins bHLH48 and bHLH60 regulate flowering under long-day conditions in Arabidopsis thaliana.
    J. Exp. Bot., 2017. 68(11): p. 2757-2767
    [PMID:28591805]