PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT3G47640.3
Common NameBHLH47, EN139, F1P2.190, PYE
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 240aa    MW: 26944.1 Da    PI: 6.5155
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT3G47640.3genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH14.75.5e-052875152
                 CHHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHH CS
          HLH  1 rrrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIk 52
                 +r ++  rEr  R+++N+ f eL + l  +    ++   Ka+iL +A++++k
  AT3G47640.3 28 KRINKAVRERLKREHLNELFIELADTLELN----QQNSGKASILCEATRFLK 75
                 689999*********************997....566778889999999887 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000831.13E-42576No hitNo description
SuperFamilySSF474594.32E-112691IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088811.5222777IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.103.4E-72794IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010106Biological Processcellular response to iron ion starvation
GO:0055072Biological Processiron ion homeostasis
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000025anatomyroot tip
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 240 aa     Download sequence    Send to blast
MVSKTPSTSS DEANATADER CRKGKVPKRI NKAVRERLKR EHLNELFIEL ADTLELNQQN  60
SGKASILCEA TRFLKDVFGQ IESLRKEHAS LLSESSYVTT EKNELKEETS VLETEISKLQ  120
NEIEARANQS KPDLNTSPAP EYHHHHYQQQ HPERVSQFPG LPIFQGPGFQ QSATTLHPPA  180
TVLVLPIQPD PQTQDISEMT QAQQPLMFNS SNVSKPCPRY ASAADSWSSR LLGERLKASE
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.439110.0root
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible252427_at0.0
Expression AtlasAT3G47640-
AtGenExpressAT3G47640-
ATTED-IIAT3G47640-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed constitutively in roots, leaves, stems, and flowers. {ECO:0000269|PubMed:12679534}.
Functional Description ? help Back to Top
Source Description
TAIREncodes POPEYE (PYE), a bHLH transcription factor regulating response to iron deficiency in Arabidopsis roots.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT3G47640.3
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Interaction ? help Back to Top
Source Intact With
BioGRIDAT4G14410, AT4G02590, AT5G08330, AT5G11260, AT5G51910, AT5G54680, AT1G03040, AT1G51070, AT1G69690
IntActSearch Q9SN74
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT3G47640
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY1140180.0AY114018.1 Arabidopsis thaliana unknown protein (At3g47640) mRNA, complete cds.
GenBankAY0807860.0AY080786.1 Arabidopsis thaliana unknown protein (At3g47640) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001190029.11e-179bHLH transcription factor POPEYE
RefseqNP_001190030.11e-179bHLH transcription factor POPEYE
RefseqNP_190348.11e-179bHLH transcription factor POPEYE
SwissprotQ9SN740.0BH047_ARATH; Transcription factor bHLH47
TrEMBLD7LRE11e-160D7LRE1_ARALL; Basic helix-loop-helix family protein
STRINGAT3G47640.11e-178(Arabidopsis thaliana)
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  5. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  6. Yang KY,Kim YM,Lee S,Song PS,Soh MS
    Overexpression of a mutant basic helix-loop-helix protein HFR1, HFR1-deltaN105, activates a branch pathway of light signaling in Arabidopsis.
    Plant Physiol., 2003. 133(4): p. 1630-42
    [PMID:14645731]
  7. Guan Y,Nothnagel EA
    Binding of arabinogalactan proteins by Yariv phenylglycoside triggers wound-like responses in Arabidopsis cell cultures.
    Plant Physiol., 2004. 135(3): p. 1346-66
    [PMID:15235117]
  8. Gong W, et al.
    The development of protein microarrays and their applications in DNA-protein and protein-protein interaction analyses of Arabidopsis transcription factors.
    Mol Plant, 2008. 1(1): p. 27-41
    [PMID:19802365]
  9. Long TA, et al.
    The bHLH transcription factor POPEYE regulates response to iron deficiency in Arabidopsis roots.
    Plant Cell, 2010. 22(7): p. 2219-36
    [PMID:20675571]
  10. Golisz A,Sugano M,Hiradate S,Fujii Y
    Microarray analysis of Arabidopsis plants in response to allelochemical L-DOPA.
    Planta, 2011. 233(2): p. 231-40
    [PMID:20978802]
  11. Arabidopsis Interactome Mapping Consortium
    Evidence for network evolution in an Arabidopsis interactome map.
    Science, 2011. 333(6042): p. 601-7
    [PMID:21798944]
  12. Ivanov R,Brumbarova T,Bauer P
    Fitting into the harsh reality: regulation of iron-deficiency responses in dicotyledonous plants.
    Mol Plant, 2012. 5(1): p. 27-42
    [PMID:21873619]
  13. Efroni I, et al.
    Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses.
    Dev. Cell, 2013. 24(4): p. 438-45
    [PMID:23449474]
  14. Selote D,Samira R,Matthiadis A,Gillikin JW,Long TA
    Iron-binding E3 ligase mediates iron response in plants by targeting basic helix-loop-helix transcription factors.
    Plant Physiol., 2015. 167(1): p. 273-86
    [PMID:25452667]