PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT3G47620.1
Common NameAtTCP14, F1P2.170, TCP14
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family TCP
Protein Properties Length: 489aa    MW: 52299.8 Da    PI: 7.1322
Description TEOSINTE BRANCHED, cycloidea and PCF (TCP) 14
Gene Model
Gene Model ID Type Source Coding Sequence
AT3G47620.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1TCP136.72e-421112892135
          TCP   2 agkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgt................................ss 67 
                  + k+ +++++hTkv+gR+RR+R++a+caar+F+L++eLG+++d++tieWLlqqa+p+++++tgt                                ++
  AT3G47620.1 111 PLKRASTKDRHTKVDGRGRRIRMPALCAARVFQLTRELGHKSDGETIEWLLQQAEPSVIAATGTgtipanftslnislrssgssmslpshfrsaasTF 208
                  57999***********************************************************6666666666666666666665555555555444 PP

          TCP  68 ssaseceaesssssasnsssg...........kaaksaa.kskksqksaasalnlakesrakararare.rtrekmriknk 135
                  s+++ +++++ ++++++++ g           +a +s+  ++ ++ ++++s+ln+++ ++++ +++++e ++++k ri++ 
  AT3G47620.1 209 SPNNIFSPAMLQQQQQQQRGGgvgfhhphlqgRAPTSSLfPGIDNFTPTTSFLNFHNPTKQEGDQDSEElNSEKKRRIQTT 289
                  44444455555555555555599999*****988899999*****************************888888888865 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF036343.6E-41116298IPR005333Transcription factor, TCP
PROSITE profilePS5136927.505117171IPR017887Transcription factor TCP subgroup
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0008283Biological Processcell proliferation
GO:0009735Biological Processresponse to cytokinin
GO:0009737Biological Processresponse to abscisic acid
GO:0009739Biological Processresponse to gibberellin
GO:0010029Biological Processregulation of seed germination
GO:0010229Biological Processinflorescence development
GO:0031347Biological Processregulation of defense response
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005515Molecular Functionprotein binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009015anatomyportion of vascular tissue
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 489 aa     Download sequence    Send to blast
MQKPTSSILN VIMDGGDSVG GGGGDDHHRH LHHHHRPTFP FQLLGKHDPD DNHQQQPSPS  60
SSSSLFSLHQ HQQLSQSQPQ SQSQKSQPQT TQKELLQTQE ESAVVAAKKP PLKRASTKDR  120
HTKVDGRGRR IRMPALCAAR VFQLTRELGH KSDGETIEWL LQQAEPSVIA ATGTGTIPAN  180
FTSLNISLRS SGSSMSLPSH FRSAASTFSP NNIFSPAMLQ QQQQQQRGGG VGFHHPHLQG  240
RAPTSSLFPG IDNFTPTTSF LNFHNPTKQE GDQDSEELNS EKKRRIQTTS DLHQQQQQHQ  300
HDQIGGYTLQ SSNSGSTATA AAAQQIPGNF WMVAAAAAAG GGGGNNNQTG GLMTASIGTG  360
GGGGEPVWTF PSINTAAAAL YRSGVSGVPS GAVSSGLHFM NFAAPMAFLT GQQQLATTSN  420
HEINEDSNNN EGGRSDGGGD HHNTQRHHHH QQQHHHNILS GLNQYGRQVS GDSQASGSLG  480
GGDEEDQQD
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1431438GGRSDGGG
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.212510.0bud| floral meristem| flower| leaf| root| vegetative tissue
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO306929000.0
Genevisible252425_at0.0
Expression AtlasAT3G47620-
AtGenExpressAT3G47620-
ATTED-IIAT3G47620-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in the vascular tissues of the embryo (PubMed:17953649). Expressed in young proliferating tissues (PubMed:21668538). {ECO:0000269|PubMed:17953649, ECO:0000269|PubMed:21668538}.
Functional Description ? help Back to Top
Source Description
TAIREncodes a transcription factor AtTCP14 that regulates seed germination. AtTCP14 shows elevated expression level just prior to germination. AtTCP14 is predominantly expressed in the vascular tissue of the embryo, and affects gene expression in radicles in a non-cell-autonomous manner.
UniProtTranscription factor involved the regulation of plant development. Together with TCP15, modulates plant stature by promoting cell division in young internodes. Represses cell proliferation in leaf and floral tissues (PubMed:21668538). Together with TCP15, acts downstream of gibberellin (GA), and the stratification pathways that promote seed germination. Involved in the control of cell proliferation at the root apical meristem (RAM) by regulating the activity of CYCB1-1 (PubMed:25655823). Involved in the regulation of seed germination. May regulate the activation of embryonic growth potential during seed germination (PubMed:17953649, PubMed:22155632). Acts together with SPY to promote cytokinin responses that affect leaf shape and trichome development in flowers (PubMed:22267487). Transcription factor involved in the regulation of endoreduplication. Represses endoreduplication by activating the gene expression of the key cell-cycle regulators RBR1 and CYCA2-3 (PubMed:25757472). Regulates the expression of the defense gene pathogenesis-related protein 2 (PR2) in antagonism to SRFR1, a negative regulator of effector-triggered immunity (PubMed:24689742). Involved in positive regulation of plant defense. Represses jasmonate (JA) response to promote disease resistance. Regulates the plant immune system by transcriptionally repressing a subset of JA-responsive genes (PubMed:28132837). {ECO:0000269|PubMed:17953649, ECO:0000269|PubMed:21668538, ECO:0000269|PubMed:22155632, ECO:0000269|PubMed:22267487, ECO:0000269|PubMed:24689742, ECO:0000269|PubMed:25655823, ECO:0000269|PubMed:25757472, ECO:0000269|PubMed:28132837}.
Function -- GeneRIF ? help Back to Top
  1. Together, the two genes, TCP14 and TCP15, influence plant stature by promoting cell division in young internodes.
    [PMID: 21668538]
  2. DOF6 negatively affects seed germination and opposes TCP14 function in the regulation of a specific set of ABA-related genes.
    [PMID: 22155632]
  3. Data suggest that responses of leaves and flowers to CK are mediated by SPY-dependent TCP14 and TCP15 activities.
    [PMID: 22267487]
  4. TCP14 and TCP15 act downstream of the gibberellins and promote seed germination.
    [PMID: 25655823]
  5. DA1, DAR1, and DAR2 physically interact with the transcription factors TCP14 and TCP15, which repress endoreduplication.
    [PMID: 25757472]
  6. posttranslational modification of TCP14/15 by SPY inhibits their proteolysis.
    [PMID: 27208284]
  7. TCP14 regulates the plant immune system by transcriptionally repressing a subset of the jasmonic acid (JA) hormone signaling outputs. The Pseudomonas syringae type III effector, HopBB1, interacts with TCP14 and targets it to the SCF(COI1) degradation complex by connecting it to the JA signaling repressor JAZ3. HopBB1 de-represses the TCP14-regulated subset of JA response genes and promotes pathogen virulence.
    [PMID: 28132837]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00396DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT3G47620.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced during seed imbibition (PubMed:17953649). Circadian-regulation with the lowest expression in the middle of the dark period (PubMed:17953649). {ECO:0000269|PubMed:17953649}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDabscisic acid, gibberellin
Interaction ? help Back to Top
Source Intact With
BioGRIDAT3G47620, AT4G18390, AT4G25440, AT5G08070, AT5G08330, AT5G17490, AT5G51910, AT5G60120, AT5G60970, AT1G05710, AT1G14920, AT1G30210, AT1G35560, AT1G53230, AT1G58100, AT1G62990, AT1G66350, AT1G69690, AT1G69810
IntActSearch Q93Z00
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT3G47620
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAL1329550.0AL132955.1 Arabidopsis thaliana DNA chromosome 3, BAC clone F1P2.
GenBankAY0588740.0AY058874.1 Arabidopsis thaliana AT3g47620/F1P2_170 mRNA, complete cds.
GenBankAY1033040.0AY103304.1 Arabidopsis thaliana AT3g47620/F1P2_170 mRNA, complete cds.
GenBankCP0026860.0CP002686.1 Arabidopsis thaliana chromosome 3, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_190346.20.0TEOSINTE BRANCHED, cycloidea and PCF (TCP) 14
SwissprotQ93Z000.0TCP14_ARATH; Transcription factor TCP14
TrEMBLA0A178V7160.0A0A178V716_ARATH; TCP14
STRINGAT3G47620.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM39152757
Representative plantOGRP26991230
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  3. Vergnolle C, et al.
    The cold-induced early activation of phospholipase C and D pathways determines the response of two distinct clusters of genes in Arabidopsis cell suspensions.
    Plant Physiol., 2005. 139(3): p. 1217-33
    [PMID:16258011]
  4. Siemens J, et al.
    Transcriptome analysis of Arabidopsis clubroots indicate a key role for cytokinins in disease development.
    Mol. Plant Microbe Interact., 2006. 19(5): p. 480-94
    [PMID:16673935]
  5. Guti
    Qualitative network models and genome-wide expression data define carbon/nitrogen-responsive molecular machines in Arabidopsis.
    Genome Biol., 2007. 8(1): p. R7
    [PMID:17217541]
  6. Aguilar-Martínez JA,Poza-Carrión C,Cubas P
    Arabidopsis BRANCHED1 acts as an integrator of branching signals within axillary buds.
    Plant Cell, 2007. 19(2): p. 458-72
    [PMID:17307924]
  7. Tatematsu K,Nakabayashi K,Kamiya Y,Nambara E
    Transcription factor AtTCP14 regulates embryonic growth potential during seed germination in Arabidopsis thaliana.
    Plant J., 2008. 53(1): p. 42-52
    [PMID:17953649]
  8. Ascencio-Ib
    Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.
    Plant Physiol., 2008. 148(1): p. 436-54
    [PMID:18650403]
  9. Hanada K, et al.
    Functional compensation of primary and secondary metabolites by duplicate genes in Arabidopsis thaliana.
    Mol. Biol. Evol., 2011. 28(1): p. 377-82
    [PMID:20736450]
  10. Kieffer M,Master V,Waites R,Davies B
    TCP14 and TCP15 affect internode length and leaf shape in Arabidopsis.
    Plant J., 2011. 68(1): p. 147-58
    [PMID:21668538]
  11. Mukhtar MS, et al.
    Independently evolved virulence effectors converge onto hubs in a plant immune system network.
    Science, 2011. 333(6042): p. 596-601
    [PMID:21798943]
  12. Arabidopsis Interactome Mapping Consortium
    Evidence for network evolution in an Arabidopsis interactome map.
    Science, 2011. 333(6042): p. 601-7
    [PMID:21798944]
  13. Rueda-Romero P,Barrero-Sicilia C,G
    Arabidopsis thaliana DOF6 negatively affects germination in non-after-ripened seeds and interacts with TCP14.
    J. Exp. Bot., 2012. 63(5): p. 1937-49
    [PMID:22155632]
  14. Steiner E, et al.
    The Arabidopsis O-linked N-acetylglucosamine transferase SPINDLY interacts with class I TCPs to facilitate cytokinin responses in leaves and flowers.
    Plant Cell, 2012. 24(1): p. 96-108
    [PMID:22267487]
  15. Steiner E, et al.
    Class I TCPs modulate cytokinin-induced branching and meristematic activity in tomato.
    Plant Signal Behav, 2012. 7(7): p. 807-10
    [PMID:22751297]
  16. Danisman S, et al.
    Analysis of functional redundancies within the Arabidopsis TCP transcription factor family.
    J. Exp. Bot., 2013. 64(18): p. 5673-85
    [PMID:24129704]
  17. Kim SH, et al.
    The Arabidopsis immune adaptor SRFR1 interacts with TCP transcription factors that redundantly contribute to effector-triggered immunity.
    Plant J., 2014. 78(6): p. 978-89
    [PMID:24689742]
  18. Mar
    Large-scale identification of gibberellin-related transcription factors defines group VII ETHYLENE RESPONSE FACTORS as functional DELLA partners.
    Plant Physiol., 2014. 166(2): p. 1022-32
    [PMID:25118255]
  19. Davi
    Class I TCP-DELLA interactions in inflorescence shoot apex determine plant height.
    Curr. Biol., 2014. 24(16): p. 1923-8
    [PMID:25127215]
  20. We
    Convergent targeting of a common host protein-network by pathogen effectors from three kingdoms of life.
    Cell Host Microbe, 2014. 16(3): p. 364-75
    [PMID:25211078]
  21. Resentini F, et al.
    TCP14 and TCP15 mediate the promotion of seed germination by gibberellins in Arabidopsis thaliana.
    Mol Plant, 2015. 8(3): p. 482-5
    [PMID:25655823]
  22. Peng Y, et al.
    The ubiquitin receptors DA1, DAR1, and DAR2 redundantly regulate endoreduplication by modulating the stability of TCP14/15 in Arabidopsis.
    Plant Cell, 2015. 27(3): p. 649-62
    [PMID:25757472]
  23. Steiner E, et al.
    The Putative O-Linked N-Acetylglucosamine Transferase SPINDLY Inhibits Class I TCP Proteolysis to Promote Sensitivity to Cytokinin.
    Plant Physiol., 2016. 171(2): p. 1485-94
    [PMID:27208284]
  24. Yang L, et al.
    Pseudomonas syringae Type III Effector HopBB1 Promotes Host Transcriptional Repressor Degradation to Regulate Phytohormone Responses and Virulence.
    Cell Host Microbe, 2017. 21(2): p. 156-168
    [PMID:28132837]
  25. Zhang N, et al.
    MOS1 functions closely with TCP transcription factors to modulate immunity and cell cycle in Arabidopsis.
    Plant J., 2018. 93(1): p. 66-78
    [PMID:29086441]
  26. Mazur MJ, et al.
    Arabidopsis TCP Transcription Factors Interact with the SUMO Conjugating Machinery in Nuclear Foci.
    Front Plant Sci, 2017. 8: p. 2043
    [PMID:29250092]