PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT3G26790.1
Common NameFUS3, MDJ14.4
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family B3
Protein Properties Length: 313aa    MW: 35615.7 Da    PI: 5.5466
Description B3 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT3G26790.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B365.39e-2192192198
                  EEEE-..-HHHHTT-EE--HHH.HTT..---..--SEEEEEETTS.-EEEEEE....EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SS.SEE.. CS
           B3   1 ffkvltpsdvlksgrlvlpkkfaeeh..ggkkeesktltledesg.rsWevkliy..rkksgryvltkGWkeFvkangLkegDfvvFkldgr.sefel 92 
                  f+k+l++sdv++++r++lpkk ae+h   ++ +e++ +++ed++g  +W++k++y  +++s++yvl+ ++ +Fv+a+gL+ gDf++ +  ++  + ++
  AT3G26790.1  92 FQKELKNSDVSSLRRMILPKKAAEAHlpALECKEGIPIRMEDLDGfHVWTFKYRYwpNNNSRMYVLE-NTGDFVNAHGLQLGDFIMVY--QDlYSNNY 186
                  99**************************777788899********9*********89999999***9.******************99..66677777 PP

                  EEEEE- CS
           B3  93 vvkvfr 98 
                  v+++++
  AT3G26790.1 187 VIQARK 192
                  877776 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.40.330.101.1E-2882199IPR015300DNA-binding pseudobarrel domain
SuperFamilySSF1019361.22E-2290195IPR015300DNA-binding pseudobarrel domain
CDDcd100177.11E-2890192No hitNo description
PROSITE profilePS508639.60192194IPR003340B3 DNA binding domain
SMARTSM010194.8E-2392194IPR003340B3 DNA binding domain
PfamPF023622.0E-1792192IPR003340B3 DNA binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010116Biological Processpositive regulation of abscisic acid biosynthetic process
GO:0010262Biological Processsomatic embryogenesis
GO:0010373Biological Processnegative regulation of gibberellin biosynthetic process
GO:0048573Biological Processphotoperiodism, flowering
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000011anatomycultured somatic plant embryo
PO:0000013anatomycauline leaf
PO:0000293anatomyguard cell
PO:0005360anatomyaleurone layer
PO:0006210anatomyprotoderm
PO:0009001anatomyfruit
PO:0009009anatomyplant embryo
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0020031anatomyradicle
PO:0020108anatomysuspensor
PO:0025022anatomycollective leaf structure
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
PO:0007632developmental stageseed maturation stage
Sequence ? help Back to Top
Protein Sequence    Length: 313 aa     Download sequence    Send to blast
MMVDENVETK ASTLVASVDH GFGSGSGHDH HGLSASVPLL GVNWKKRRMP RQRRSSSSFN  60
LLSFPPPMPP ISHVPTPLPA RKIDPRKLRF LFQKELKNSD VSSLRRMILP KKAAEAHLPA  120
LECKEGIPIR MEDLDGFHVW TFKYRYWPNN NSRMYVLENT GDFVNAHGLQ LGDFIMVYQD  180
LYSNNYVIQA RKASEEEEVD VINLEEDDVY TNLTRIENTV VNDLLLQDFN HHNNNNNNNS  240
NSNSNKCSYY YPVIDDVTTN TESFVYDTTA LTSNDTPLDF LGGHTTTTNN YYSKFGTFDG  300
LGSVENISLD DFY
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6j9b_A7e-81882021115B3 domain-containing transcription factor FUS3
6j9b_D7e-81882021115B3 domain-containing transcription factor FUS3
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.60290.0seed| silique
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO306884970.0
Genevisible258258_at0.0
Expression AtlasAT3G26790-
AtGenExpressAT3G26790-
ATTED-IIAT3G26790-
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in developing embryo. At globular stage, expressed in all cells of the embryo proper. At heart stage, preferentially expressed in the protodermal tissue. In mature embryo, expressed in the provascular tissue, root cap and mature epidermis. Expressed in the aleurone layer in mature seed. Expressed in leaf primordia and shoot apical meristem (PubMed:22026387). {ECO:0000269|PubMed:14675433, ECO:0000269|PubMed:22026387, ECO:0000269|PubMed:9807814}.
UniprotTISSUE SPECIFICITY: Expressed in cotyledons and hypocotyls. {ECO:0000269|PubMed:22026387}.
Functional Description ? help Back to Top
Source Description
TAIRTranscriptional factor with high similarity to the B3 region of the VP1/ABI3-like proteins. Full length FUS3 protein binds to the highly conserved RY motif [DNA motif CATGCA(TG)], present in many seed-specific promoters, and the B3 domains of this transcription factor is necessary for the specific interaction with the RY element. Transcriptional activity of FUS3 requires the B3 DNA-binding domain and an activation domain. FUS3 specifies cotyledon identity. Regulator of gene expression during late embryogenesis. Involved in the control foliar organ identity in Arabidopsis by regulating the synthesis of two hormones, abscisic acid and gibberellin. FUS3 together with LEC1 positively regulate the abundance of the ABI3 protein in the seed.
UniProtTranscription regulator involved in gene regulation during late embryogenesis. Its expression to the epidermis is sufficient to control foliar organ identity by regulating positively the synthesis abscisic acid (ABA) and negatively gibberellin production. Negatively regulates TTG1 in the embryo. Positively regulates the abundance of the ABI3 protein in the seed. Cooperates with KIN10 to regulate developmental phase transitions and lateral organ development and act both as positive regulators of abscisic acid (ABA) signaling during germination (PubMed:22026387, PubMed:22902692). {ECO:0000269|PubMed:14675433, ECO:0000269|PubMed:15363412, ECO:0000269|PubMed:22026387, ECO:0000269|PubMed:22902692}.
Function -- GeneRIF ? help Back to Top
  1. In this study, it was shown that gibberellin (GA) hormone biosynthesis is regulated by LEC2 and FUS3 pathways.
    [PMID: 15516508]
  2. At2S3 activation by FUS3 was rapid but CRC induction by FUS3 with abscissic acid[ABA] and by ABA followed by presence of FUS3 took longer, suggesting involvement of an indirect mechanism requiring the synthesis of intermediate regulatory factor(s)
    [PMID: 15695463]
  3. Total repression of embryogenic potential was observed in double (lec1 lec2, lec1 fus3, lec2 fus3) and triple (fus3 lec1 lec2) mutants.
    [PMID: 16034595]
  4. Results show that Significant differences in histone modifications at the phas promoter were mediated by FUS3 and PvALF, suggesting that they function through different epigenetic mechanisms.
    [PMID: 18038114]
  5. FUS3 function is restricted to the acquisition of embryo-dependent seed dormancy, the determination of cotyledonary cell identity, and the synthesis and accumulation of storage compounds.
    [PMID: 18343361]
  6. The C-terminal domain is required for normal FUS3 function and sensitivity to abscisic acid and gibberellic acid, and negatively regulates mRNA and protein levels.
    [PMID: 20663088]
  7. The genes positively controlled by FUS3 are not confined to previously known seed maturation-related genes and include those involved in the production of secondary metabolites and those involved in primary metabolism.
    [PMID: 21045071]
  8. FUS3 is phosphorylated by AKIN10. AKIN10 overexpression delays FUS3 degradation. AKIN10 and FUS3 function interactively to promote seed maturation, dormancy and inhibit developmental phase transitions.
    [PMID: 22026387]
  9. FUS3 contributes to the delay of seed germination at high temperature.
    [PMID: 22279962]
  10. Activation of FUS3 after germination dampens the expression of genes involved in the biosynthesis and response to the plant hormone ethylene, whereas a loss-of-function fus3 mutant shows many phenotypes consistent with increased ethylene signaling.
    [PMID: 22348746]
  11. FUS3 and AKIN10 functionally overlap in abscissic acid signaling, but play different roles in sugar responses during germination.
    [PMID: 22902692]
  12. Examination of direct targets of FUS3 reveals that FUS3 acts primarily or exclusively as a transcriptional activator.
    [PMID: 23314941]
  13. TT2 is directly bound to the regulatory region of FUSCA3, and mediates the expression of numerous genes in the fatty acid biosynthesis pathway.
    [PMID: 24397827]
  14. This study examined the role of ABSCISIC ACID INSENSITIVE3 (ABI3), FUSCA3 (FUS3) and LEAFY COTYLEDON2 (LEC2), in the production of seed reserves in Arabidopsis.
    [PMID: 25840088]
  15. LEC1, LEC2 , and FUSCA3 transcripts are candidate targets of VAL1, acting through epigenetic and/or transcriptional repression.
    [PMID: 26678037]
  16. LEAFY COTYLEDON2 (LEC2) was identified as an interacting factor of FUS3, and demonstrated that these two homologous B3 transcription factors interact to bind to the auxin biosynthesis gene YUCCA4 (YUC4) and synergistically activate its transcription during lateral roots formation.
    [PMID: 27878992]
  17. AIP2 targets FUS3 for degradation and plays a role in cotyledon development and flowering time in Arabidopsis.
    [PMID: 28369580]
  18. FUS3 phosphorylation and SnRK1 are required for embryogenesis and integration of environmental cues to ensure the survival of the progeny.
    [PMID: 28922765]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00382DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT3G26790.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Upstream Regulators) ? help Back to Top
Source Upstream Regulator (A: Activate/R: Repress)
ATRM AT1G21970 (A), AT1G28300 (A), AT1G54060 (R), AT3G24650 (A), AT3G26790 (A)
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT1G06180(R), AT1G15550(R), AT1G62290(A), AT1G69180(A), AT1G80340(R), AT2G40170(A), AT2G41260(A), AT3G24650(A), AT3G26790(A), AT3G51810(R), AT4G27160(A), AT5G24520(R), AT5G65165(A), AT5G66400(A), AT5G67300(A)
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDabscisic acid, auxin
Interaction ? help Back to Top
Source Intact With
BioGRIDAT5G56780
Phenotype -- Disruption Phenotype ? help Back to Top
Source Description
UniProtDISRUPTION PHENOTYPE: Accumulation of anthocyanins in embryo. Presence of trichomes on cotyledons. Unusual pattern of storage product accumulation in embryos and cotyledons. {ECO:0000269|PubMed:12244252}.
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT3G26790
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF0162650.0AF016265.1 Arabidopsis thaliana FUSCA3 (FUS3) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_566799.10.0AP2/B3-like transcriptional factor family protein
SwissprotQ9LW310.0FUS3_ARATH; B3 domain-containing transcription factor FUS3
TrEMBLA0A178VEF10.0A0A178VEF1_ARATH; FUS3
STRINGAT3G26790.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM71382638
Representative plantOGRP7881766
Publications ? help Back to Top
  1. Wobus U,Weber H
    Seed maturation: genetic programmes and control signals.
    Curr. Opin. Plant Biol., 1999. 2(1): p. 33-8
    [PMID:10047566]
  2. Rohde A, et al.
    ABI3 affects plastid differentiation in dark-grown Arabidopsis seedlings.
    Plant Cell, 2000. 12(1): p. 35-52
    [PMID:10634906]
  3. Kurup S,Jones HD,Holdsworth MJ
    Interactions of the developmental regulator ABI3 with proteins identified from developing Arabidopsis seeds.
    Plant J., 2000. 21(2): p. 143-55
    [PMID:10743655]
  4. Nambara E, et al.
    The role of ABI3 and FUS3 loci in Arabidopsis thaliana on phase transition from late embryo development to germination.
    Dev. Biol., 2000. 220(2): p. 412-23
    [PMID:10753527]
  5. Reidt W, et al.
    Gene regulation during late embryogenesis: the RY motif of maturation-specific gene promoters is a direct target of the FUS3 gene product.
    Plant J., 2000. 21(5): p. 401-8
    [PMID:10758492]
  6. Wehmeyer N,Vierling E
    The expression of small heat shock proteins in seeds responds to discrete developmental signals and suggests a general protective role in desiccation tolerance.
    Plant Physiol., 2000. 122(4): p. 1099-108
    [PMID:10759505]
  7. Vicient CM,Bies-Etheve N,Delseny M
    Changes in gene expression in the leafy cotyledon1 (lec1) and fusca3 (fus3) mutants of Arabidopsis thaliana L.
    J. Exp. Bot., 2000. 51(347): p. 995-1003
    [PMID:10948227]
  8. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  9. Raz V,Bergervoet JH,Koornneef M
    Sequential steps for developmental arrest in Arabidopsis seeds.
    Development, 2001. 128(2): p. 243-52
    [PMID:11124119]
  10. Hong SW,Vierling E
    Hsp101 is necessary for heat tolerance but dispensable for development and germination in the absence of stress.
    Plant J., 2001. 27(1): p. 25-35
    [PMID:11489180]
  11. Ikeda-Iwai M,Satoh S,Kamada H
    Establishment of a reproducible tissue culture system for the induction of Arabidopsis somatic embryos.
    J. Exp. Bot., 2002. 53(374): p. 1575-80
    [PMID:12096096]
  12. Keith K,Kraml M,Dengler NG,McCourt P
    fusca3: A Heterochronic Mutation Affecting Late Embryo Development in Arabidopsis.
    Plant Cell, 1994. 6(5): p. 589-600
    [PMID:12244252]
  13. Meinke DW,Franzmann LH,Nickle TC,Yeung EC
    Leafy Cotyledon Mutants of Arabidopsis.
    Plant Cell, 1994. 6(8): p. 1049-1064
    [PMID:12244265]
  14. Brocard-Gifford IM,Lynch TJ,Finkelstein RR
    Regulatory networks in seeds integrating developmental, abscisic acid, sugar, and light signaling.
    Plant Physiol., 2003. 131(1): p. 78-92
    [PMID:12529517]
  15. Ikeda-Iwai M,Umehara M,Satoh S,Kamada H
    Stress-induced somatic embryogenesis in vegetative tissues of Arabidopsis thaliana.
    Plant J., 2003. 34(1): p. 107-14
    [PMID:12662313]
  16. Dean Rider S, et al.
    Coordinate repression of regulators of embryonic identity by PICKLE during germination in Arabidopsis.
    Plant J., 2003. 35(1): p. 33-43
    [PMID:12834400]
  17. Kroj T,Savino G,Valon C,Giraudat J,Parcy F
    Regulation of storage protein gene expression in Arabidopsis.
    Development, 2003. 130(24): p. 6065-73
    [PMID:14597573]
  18. Tsuchiya Y,Nambara E,Naito S,McCourt P
    The FUS3 transcription factor functions through the epidermal regulator TTG1 during embryogenesis in Arabidopsis.
    Plant J., 2004. 37(1): p. 73-81
    [PMID:14675433]
  19. Baumbusch LO,Hughes DW,Galau GA,Jakobsen KS
    LEC1, FUS3, ABI3 and Em expression reveals no correlation with dormancy in Arabidopsis.
    J. Exp. Bot., 2004. 55(394): p. 77-87
    [PMID:14676287]
  20. Mönke G, et al.
    Seed-specific transcription factors ABI3 and FUS3: molecular interaction with DNA.
    Planta, 2004. 219(1): p. 158-66
    [PMID:14767767]
  21. Gong W, et al.
    Genome-wide ORFeome cloning and analysis of Arabidopsis transcription factor genes.
    Plant Physiol., 2004. 135(2): p. 773-82
    [PMID:15208423]
  22. Gazzarrini S,Tsuchiya Y,Lumba S,Okamoto M,McCourt P
    The transcription factor FUSCA3 controls developmental timing in Arabidopsis through the hormones gibberellin and abscisic acid.
    Dev. Cell, 2004. 7(3): p. 373-85
    [PMID:15363412]
  23. Curaba J, et al.
    AtGA3ox2, a key gene responsible for bioactive gibberellin biosynthesis, is regulated during embryogenesis by LEAFY COTYLEDON2 and FUSCA3 in Arabidopsis.
    Plant Physiol., 2004. 136(3): p. 3660-9
    [PMID:15516508]
  24. Kagaya Y, et al.
    LEAFY COTYLEDON1 controls seed storage protein genes through its regulation of FUSCA3 and ABSCISIC ACID INSENSITIVE3.
    Plant Cell Physiol., 2005. 46(3): p. 399-406
    [PMID:15695450]
  25. Kagaya Y, et al.
    Indirect ABA-dependent regulation of seed storage protein genes by FUSCA3 transcription factor in Arabidopsis.
    Plant Cell Physiol., 2005. 46(2): p. 300-11
    [PMID:15695463]
  26. Nambara E,Marion-Poll A
    Abscisic acid biosynthesis and catabolism.
    Annu Rev Plant Biol, 2005. 56: p. 165-85
    [PMID:15862093]
  27. Tsukagoshi H,Saijo T,Shibata D,Morikami A,Nakamura K
    Analysis of a sugar response mutant of Arabidopsis identified a novel B3 domain protein that functions as an active transcriptional repressor.
    Plant Physiol., 2005. 138(2): p. 675-85
    [PMID:15894743]
  28. Gaj MD,Zhang S,Harada JJ,Lemaux PG
    Leafy cotyledon genes are essential for induction of somatic embryogenesis of Arabidopsis.
    Planta, 2005. 222(6): p. 977-88
    [PMID:16034595]
  29. Santos Mendoza M,Dubreucq B,Miquel M,Caboche M,Lepiniec L
    LEAFY COTYLEDON 2 activation is sufficient to trigger the accumulation of oil and seed specific mRNAs in Arabidopsis leaves.
    FEBS Lett., 2005. 579(21): p. 4666-70
    [PMID:16107256]
  30. To A, et al.
    A network of local and redundant gene regulation governs Arabidopsis seed maturation.
    Plant Cell, 2006. 18(7): p. 1642-51
    [PMID:16731585]
  31. Makarevich G, et al.
    Different Polycomb group complexes regulate common target genes in Arabidopsis.
    EMBO Rep., 2006. 7(9): p. 947-52
    [PMID:16878125]
  32. Suzuki M,Wang HH,McCarty DR
    Repression of the LEAFY COTYLEDON 1/B3 regulatory network in plant embryo development by VP1/ABSCISIC ACID INSENSITIVE 3-LIKE B3 genes.
    Plant Physiol., 2007. 143(2): p. 902-11
    [PMID:17158584]
  33. Cao X, et al.
    Abscisic acid and stress signals induce Viviparous1 expression in seed and vegetative tissues of maize.
    Plant Physiol., 2007. 143(2): p. 720-31
    [PMID:17208960]
  34. Wang H,Guo J,Lambert KN,Lin Y
    Developmental control of Arabidopsis seed oil biosynthesis.
    Planta, 2007. 226(3): p. 773-83
    [PMID:17522888]
  35. Tanaka M,Kikuchi A,Kamada H
    The Arabidopsis histone deacetylases HDA6 and HDA19 contribute to the repression of embryonic properties after germination.
    Plant Physiol., 2008. 146(1): p. 149-61
    [PMID:18024558]
  36. W-K Ng D,Hall TC
    PvALF and FUS3 activate expression from the phaseolin promoter by different mechanisms.
    Plant Mol. Biol., 2008. 66(3): p. 233-44
    [PMID:18038114]
  37. Moreno-Risueno MA, et al.
    FUSCA3 from barley unveils a common transcriptional regulation of seed-specific genes between cereals and Arabidopsis.
    Plant J., 2008. 53(6): p. 882-94
    [PMID:18047557]
  38. Schallau A, et al.
    Phylogenetic footprints in fern spore- and seed-specific gene promoters.
    Plant J., 2008. 53(3): p. 414-24
    [PMID:18086283]
  39. Suzuki M, et al.
    The Maize Viviparous8 locus, encoding a putative ALTERED MERISTEM PROGRAM1-like peptidase, regulates abscisic acid accumulation and coordinates embryo and endosperm development.
    Plant Physiol., 2008. 146(3): p. 1193-206
    [PMID:18203869]
  40. Bies-Eth
    Inventory, evolution and expression profiling diversity of the LEA (late embryogenesis abundant) protein gene family in Arabidopsis thaliana.
    Plant Mol. Biol., 2008. 67(1-2): p. 107-24
    [PMID:18265943]
  41. Sreenivasulu N, et al.
    Barley grain maturation and germination: metabolic pathway and regulatory network commonalities and differences highlighted by new MapMan/PageMan profiling tools.
    Plant Physiol., 2008. 146(4): p. 1738-58
    [PMID:18281415]
  42. Stone SL, et al.
    Arabidopsis LEAFY COTYLEDON2 induces maturation traits and auxin activity: Implications for somatic embryogenesis.
    Proc. Natl. Acad. Sci. U.S.A., 2008. 105(8): p. 3151-6
    [PMID:18287041]
  43. Tiedemann J, et al.
    Dissection of a complex seed phenotype: novel insights of FUSCA3 regulated developmental processes.
    Dev. Biol., 2008. 317(1): p. 1-12
    [PMID:18343361]
  44. Holdsworth MJ,Bentsink L,Soppe WJ
    Molecular networks regulating Arabidopsis seed maturation, after-ripening, dormancy and germination.
    New Phytol., 2008. 179(1): p. 33-54
    [PMID:18422904]
  45. Santos-Mendoza M, et al.
    Deciphering gene regulatory networks that control seed development and maturation in Arabidopsis.
    Plant J., 2008. 54(4): p. 608-20
    [PMID:18476867]
  46. Kim DH, et al.
    SOMNUS, a CCCH-type zinc finger protein in Arabidopsis, negatively regulates light-dependent seed germination downstream of PIL5.
    Plant Cell, 2008. 20(5): p. 1260-77
    [PMID:18487351]
  47. Tang X, et al.
    The Arabidopsis BRAHMA chromatin-remodeling ATPase is involved in repression of seed maturation genes in leaves.
    Plant Physiol., 2008. 147(3): p. 1143-57
    [PMID:18508955]
  48. Swaminathan K,Peterson K,Jack T
    The plant B3 superfamily.
    Trends Plant Sci., 2008. 13(12): p. 647-55
    [PMID:18986826]
  49. Gao MJ, et al.
    Repression of seed maturation genes by a trihelix transcriptional repressor in Arabidopsis seedlings.
    Plant Cell, 2009. 21(1): p. 54-71
    [PMID:19155348]
  50. Roschzttardtz H, et al.
    A nuclear gene encoding the iron-sulfur subunit of mitochondrial complex II is regulated by B3 domain transcription factors during seed development in Arabidopsis.
    Plant Physiol., 2009. 150(1): p. 84-95
    [PMID:19261733]
  51. Zheng Y,Ren N,Wang H,Stromberg AJ,Perry SE
    Global identification of targets of the Arabidopsis MADS domain protein AGAMOUS-Like15.
    Plant Cell, 2009. 21(9): p. 2563-77
    [PMID:19767455]
  52. Le BH, et al.
    Global analysis of gene activity during Arabidopsis seed development and identification of seed-specific transcription factors.
    Proc. Natl. Acad. Sci. U.S.A., 2010. 107(18): p. 8063-70
    [PMID:20385809]
  53. Lu QS, et al.
    The C-terminal domain of FUSCA3 negatively regulates mRNA and protein levels, and mediates sensitivity to the hormones abscisic acid and gibberellic acid in Arabidopsis.
    Plant J., 2010. 64(1): p. 100-13
    [PMID:20663088]
  54. Yamamoto A, et al.
    Diverse roles and mechanisms of gene regulation by the Arabidopsis seed maturation master regulator FUS3 revealed by microarray analysis.
    Plant Cell Physiol., 2010. 51(12): p. 2031-46
    [PMID:21045071]
  55. Yang Y,Karlson DT
    Overexpression of AtCSP4 affects late stages of embryo development in Arabidopsis.
    J. Exp. Bot., 2011. 62(6): p. 2079-91
    [PMID:21282328]
  56. Willmann MR,Mehalick AJ,Packer RL,Jenik PD
    MicroRNAs regulate the timing of embryo maturation in Arabidopsis.
    Plant Physiol., 2011. 155(4): p. 1871-84
    [PMID:21330492]
  57. Tsai AY,Gazzarrini S
    AKIN10 and FUSCA3 interact to control lateral organ development and phase transitions in Arabidopsis.
    Plant J., 2012. 69(5): p. 809-21
    [PMID:22026387]
  58. Tang X, et al.
    Synergistic repression of the embryonic programme by SET DOMAIN GROUP 8 and EMBRYONIC FLOWER 2 in Arabidopsis seedlings.
    J. Exp. Bot., 2012. 63(3): p. 1391-404
    [PMID:22162868]
  59. Ivanov R,Tiedemann J,Czihal A,Baumlein H
    Transcriptional regulator AtET2 is required for the induction of dormancy during late seed development.
    J. Plant Physiol., 2012. 169(5): p. 501-8
    [PMID:22226340]
  60. Gao MJ, et al.
    ASIL1 is required for proper timing of seed filling in Arabidopsis.
    Plant Signal Behav, 2011. 6(12): p. 1886-8
    [PMID:22231199]
  61. Chiu RS,Nahal H,Provart NJ,Gazzarrini S
    The role of the Arabidopsis FUSCA3 transcription factor during inhibition of seed germination at high temperature.
    BMC Plant Biol., 2012. 12: p. 15
    [PMID:22279962]
  62. Lumba S, et al.
    The embryonic leaf identity gene FUSCA3 regulates vegetative phase transitions by negatively modulating ethylene-regulated gene expression in Arabidopsis.
    BMC Biol., 2012. 10: p. 8
    [PMID:22348746]
  63. Veerappan V, et al.
    A novel HSI2 mutation in Arabidopsis affects the PHD-like domain and leads to derepression of seed-specific gene expression.
    Planta, 2012. 236(1): p. 1-17
    [PMID:22476218]
  64. M
    Toward the identification and regulation of the Arabidopsis thaliana ABI3 regulon.
    Nucleic Acids Res., 2012. 40(17): p. 8240-54
    [PMID:22730287]
  65. Chen M, et al.
    The effect of transparent TESTA2 on seed fatty acid biosynthesis and tolerance to environmental stresses during young seedling establishment in Arabidopsis.
    Plant Physiol., 2012. 160(2): p. 1023-36
    [PMID:22879396]
  66. Tsai AY,Gazzarrini S
    Overlapping and distinct roles of AKIN10 and FUSCA3 in ABA and sugar signaling during seed germination.
    Plant Signal Behav, 2012. 7(10): p. 1238-42
    [PMID:22902692]
  67. Wang F,Perry SE
    Identification of direct targets of FUSCA3, a key regulator of Arabidopsis seed development.
    Plant Physiol., 2013. 161(3): p. 1251-64
    [PMID:23314941]
  68. Li-Beisson Y, et al.
    Acyl-lipid metabolism.
    Arabidopsis Book, 2013. 11: p. e0161
    [PMID:23505340]
  69. Yang C, et al.
    VAL- and AtBMI1-mediated H2Aub initiate the switch from embryonic to postgerminative growth in Arabidopsis.
    Curr. Biol., 2013. 23(14): p. 1324-9
    [PMID:23810531]
  70. Jia H,McCarty DR,Suzuki M
    Distinct roles of LAFL network genes in promoting the embryonic seedling fate in the absence of VAL repression.
    Plant Physiol., 2013. 163(3): p. 1293-305
    [PMID:24043445]
  71. Kim HU, et al.
    Ectopic overexpression of castor bean LEAFY COTYLEDON2 (LEC2) in Arabidopsis triggers the expression of genes that encode regulators of seed maturation and oil body proteins in vegetative tissues.
    FEBS Open Bio, 2013. 4: p. 25-32
    [PMID:24363987]
  72. Wang Z, et al.
    TRANSPARENT TESTA2 regulates embryonic fatty acid biosynthesis by targeting FUSCA3 during the early developmental stage of Arabidopsis seeds.
    Plant J., 2014. 77(5): p. 757-69
    [PMID:24397827]
  73. Rikiishi K,Maekawa M
    Seed maturation regulators are related to the control of seed dormancy in wheat (Triticum aestivum L.).
    PLoS ONE, 2014. 9(9): p. e107618
    [PMID:25211528]
  74. Yamamoto A, et al.
    Cell-by-cell developmental transition from embryo to post-germination phase revealed by heterochronic gene expression and ER-body formation in Arabidopsis leafy cotyledon mutants.
    Plant Cell Physiol., 2014. 55(12): p. 2112-25
    [PMID:25282558]
  75. Shen Y,Devic M,Lepiniec L,Zhou DX
    Chromodomain, Helicase and DNA-binding CHD1 protein, CHR5, are involved in establishing active chromatin state of seed maturation genes.
    Plant Biotechnol. J., 2015. 13(6): p. 811-20
    [PMID:25581843]
  76. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]
  77. Roscoe TT,Guilleminot J,Bessoule JJ,Berger F,Devic M
    Complementation of Seed Maturation Phenotypes by Ectopic Expression of ABSCISIC ACID INSENSITIVE3, FUSCA3 and LEAFY COTYLEDON2 in Arabidopsis.
    Plant Cell Physiol., 2015. 56(6): p. 1215-28
    [PMID:25840088]
  78. Chen M, et al.
    TRANSPARENT TESTA GLABRA1 Regulates the Accumulation of Seed Storage Reserves in Arabidopsis.
    Plant Physiol., 2015. 169(1): p. 391-402
    [PMID:26152712]
  79. Schneider A, et al.
    Potential targets of VIVIPAROUS1/ABI3-LIKE1 (VAL1) repression in developing Arabidopsis thaliana embryos.
    Plant J., 2016. 85(2): p. 305-19
    [PMID:26678037]
  80. Baud S, et al.
    Deciphering the Molecular Mechanisms Underpinning the Transcriptional Control of Gene Expression by Master Transcriptional Regulators in Arabidopsis Seed.
    Plant Physiol., 2016. 171(2): p. 1099-112
    [PMID:27208266]
  81. Zhang M,Cao X,Jia Q,Ohlrogge J
    FUSCA3 activates triacylglycerol accumulation in Arabidopsis seedlings and tobacco BY2 cells.
    Plant J., 2016. 88(1): p. 95-107
    [PMID:27288837]
  82. Fatihi A, et al.
    Deciphering and modifying LAFL transcriptional regulatory network in seed for improving yield and quality of storage compounds.
    Plant Sci., 2016. 250: p. 198-204
    [PMID:27457996]
  83. Chiu RS,Pan S,Zhao R,Gazzarrini S
    ABA-dependent inhibition of the ubiquitin proteasome system during germination at high temperature in Arabidopsis.
    Plant J., 2016. 88(5): p. 749-761
    [PMID:27496613]
  84. Tang LP, et al.
    FUSCA3 interacting with LEAFY COTYLEDON2 controls lateral root formation through regulating YUCCA4 gene expression in Arabidopsis thaliana.
    New Phytol., 2017. 213(4): p. 1740-1754
    [PMID:27878992]
  85. Duong S,Vonapartis E,Li CY,Patel S,Gazzarrini S
    The E3 ligase ABI3-INTERACTING PROTEIN2 negatively regulates FUSCA3 and plays a role in cotyledon development in Arabidopsis thaliana.
    J. Exp. Bot., 2017. 68(7): p. 1555-1567
    [PMID:28369580]
  86. Han JD, et al.
    Evolutionary Analysis of the LAFL Genes Involved in the Land Plant Seed Maturation Program.
    Front Plant Sci, 2017. 8: p. 439
    [PMID:28421087]
  87. Sun F, et al.
    Functional Characterization of TaFUSCA3, a B3-Superfamily Transcription Factor Gene in the Wheat.
    Front Plant Sci, 2017. 8: p. 1133
    [PMID:28702045]
  88. Horstman A, et al.
    The BABY BOOM Transcription Factor Activates the LEC1-ABI3-FUS3-LEC2 Network to Induce Somatic Embryogenesis.
    Plant Physiol., 2017. 175(2): p. 848-857
    [PMID:28830937]
  89. Chan A, et al.
    SnRK1 phosphorylation of FUSCA3 positively regulates embryogenesis, seed yield, and plant growth at high temperature in Arabidopsis.
    J. Exp. Bot., 2017. 68(15): p. 4219-4231
    [PMID:28922765]
  90. Geilen K,Heilmann M,Hillmer S,Böhmer M
    WRKY43 regulates polyunsaturated fatty acid content and seed germination under unfavourable growth conditions.
    Sci Rep, 2017. 7(1): p. 14235
    [PMID:29079824]
  91. Hanano A,Almousally I,Shaban M,Murphy DJ
    Arabidopsis plants exposed to dioxin result in a WRINKLED seed phenotype due to 20S proteasomal degradation of WRI1.
    J. Exp. Bot., 2018. 69(7): p. 1781-1794
    [PMID:29394403]
  92. Chen N,Veerappan V,Abdelmageed H,Kang M,Allen RD
    HSI2/VAL1 Silences AGL15 to Regulate the Developmental Transition from Seed Maturation to Vegetative Growth in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 600-619
    [PMID:29475938]
  93. Kirik V,K
    Two new oleosin isoforms with altered expression patterns in seeds of the Arabidopsis mutant fus3.
    Plant Mol. Biol., 1996. 31(2): p. 413-7
    [PMID:8756606]
  94. Parcy F,Valon C,Kohara A,Miséra S,Giraudat J
    The ABSCISIC ACID-INSENSITIVE3, FUSCA3, and LEAFY COTYLEDON1 loci act in concert to control multiple aspects of Arabidopsis seed development.
    Plant Cell, 1997. 9(8): p. 1265-77
    [PMID:9286105]
  95. Kirik V,K
    Two novel MYB homologues with changed expression in late embryogenesis-defective Arabidopsis mutants.
    Plant Mol. Biol., 1998. 37(5): p. 819-27
    [PMID:9678577]
  96. Kirik V,K
    Ectopic expression of a novel MYB gene modifies the architecture of the Arabidopsis inflorescence.
    Plant J., 1998. 13(6): p. 729-42
    [PMID:9681014]
  97. Luerssen H,Kirik V,Herrmann P,Miséra S
    FUSCA3 encodes a protein with a conserved VP1/AB13-like B3 domain which is of functional importance for the regulation of seed maturation in Arabidopsis thaliana.
    Plant J., 1998. 15(6): p. 755-64
    [PMID:9807814]