PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT3G23230.1
Common NameAtERF98, AtTDR1, ERF098, ERF98, K14B15.14, TDR1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family ERF
Protein Properties Length: 139aa    MW: 16096.5 Da    PI: 7.5189
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT3G23230.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP265.21.3e-201970256
          AP2  2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkklege 56
                 +++GVr+++ +g+++AeIrdps ng  +r +lg+f taeeAa+a+++a+ +l+g+
  AT3G23230.1 19 RFRGVRRRP-WGKFAAEIRDPSRNG--ARLWLGTFETAEEAARAYDRAAFNLRGH 70
                 69*******.**********98887..**************************97 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000183.50E-281878No hitNo description
Gene3DG3DSA:3.30.730.102.0E-311979IPR001471AP2/ERF domain
SMARTSM003805.2E-371983IPR001471AP2/ERF domain
PfamPF008476.3E-151970IPR001471AP2/ERF domain
PROSITE profilePS5103224.6841977IPR001471AP2/ERF domain
SuperFamilySSF541711.18E-231978IPR016177DNA-binding domain
PRINTSPR003673.5E-112031IPR001471AP2/ERF domain
PRINTSPR003673.5E-114359IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009873Biological Processethylene-activated signaling pathway
GO:0010200Biological Processresponse to chitin
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000037anatomyshoot apex
PO:0000293anatomyguard cell
PO:0009005anatomyroot
PO:0009025anatomyvascular leaf
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0007064developmental stageLP.12 twelve leaves visible stage
Sequence ? help Back to Top
Protein Sequence    Length: 139 aa     Download sequence    Send to blast
MESSNRSSNN QSQDDKQARF RGVRRRPWGK FAAEIRDPSR NGARLWLGTF ETAEEAARAY  60
DRAAFNLRGH LAILNFPNEY YPRMDDYSLR PPYASSSSSS SSGSTSTNVS RQNQREVFEF  120
EYLDDKVLEE LLDSEERKR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5wx9_A2e-321712712114Ethylene-responsive transcription factor ERF096
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.377410.0root
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible257918_at1e-143
Expression AtlasAT3G23230-
AtGenExpressAT3G23230-
ATTED-IIAT3G23230-
Functional Description ? help Back to Top
Source Description
TAIRencodes a member of the ERF (ethylene response factor) subfamily B-3 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 18 members in this subfamily including ATERF-1, ATERF-2, AND ATERF-5.
UniProtProbably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.
Function -- GeneRIF ? help Back to Top
  1. ERF98 is a transcriptional activator, and its C-terminal region (CMIX-1) is involved in transcriptional activation. [ERF98]
    [PMID: 22321262]
  2. The regulation of AtERF98 in Ascorbic acid biosynthesis contributes to enhanced salt tolerance in Arabidopsis. [ERF98]
    [PMID: 22417285]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT3G23230.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDethylene
Interaction ? help Back to Top
Source Intact With
BioGRIDAT5G11260
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT3G23230
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0256080.0AB025608.1 Arabidopsis thaliana genomic DNA, chromosome 3, TAC clone:K14B15.
GenBankAJ5803770.0AJ580377.1 Arabidopsis thaliana mRNA for putative ethylene responsive element binding protein.
GenBankCP0026860.0CP002686.1 Arabidopsis thaliana chromosome 3, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_188964.22e-97Integrase-type DNA-binding superfamily protein
SwissprotQ9LTC52e-98ERF98_ARATH; Ethylene-responsive transcription factor ERF098
TrEMBLA0A178VBH26e-95A0A178VBH2_ARATH; TDR1
STRINGAT3G23230.19e-97(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM10281650
Representative plantOGRP6161718
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Dal Bosco C, et al.
    Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana.
    J. Biol. Chem., 2004. 279(2): p. 1060-9
    [PMID:14576160]
  3. Gong W, et al.
    Genome-wide ORFeome cloning and analysis of Arabidopsis transcription factor genes.
    Plant Physiol., 2004. 135(2): p. 773-82
    [PMID:15208423]
  4. McGrath KC, et al.
    Repressor- and activator-type ethylene response factors functioning in jasmonate signaling and disease resistance identified via a genome-wide screen of Arabidopsis transcription factor gene expression.
    Plant Physiol., 2005. 139(2): p. 949-59
    [PMID:16183832]
  5. Vanderauwera S, et al.
    Genome-wide analysis of hydrogen peroxide-regulated gene expression in Arabidopsis reveals a high light-induced transcriptional cluster involved in anthocyanin biosynthesis.
    Plant Physiol., 2005. 139(2): p. 806-21
    [PMID:16183842]
  6. Suzuki N, et al.
    Enhanced tolerance to environmental stress in transgenic plants expressing the transcriptional coactivator multiprotein bridging factor 1c.
    Plant Physiol., 2005. 139(3): p. 1313-22
    [PMID:16244138]
  7. Nakano T,Suzuki K,Fujimura T,Shinshi H
    Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
    Plant Physiol., 2006. 140(2): p. 411-32
    [PMID:16407444]
  8. Ma S,Gong Q,Bohnert HJ
    Dissecting salt stress pathways.
    J. Exp. Bot., 2006. 57(5): p. 1097-107
    [PMID:16510518]
  9. Dombrecht B, et al.
    MYC2 differentially modulates diverse jasmonate-dependent functions in Arabidopsis.
    Plant Cell, 2007. 19(7): p. 2225-45
    [PMID:17616737]
  10. Zhao J, et al.
    Analysis of gene expression profiles in response to Sclerotinia sclerotiorum in Brassica napus.
    Planta, 2007. 227(1): p. 13-24
    [PMID:17665211]
  11. Libault M,Wan J,Czechowski T,Udvardi M,Stacey G
    Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-ligase genes responding to chitin, a plant-defense elicitor.
    Mol. Plant Microbe Interact., 2007. 20(8): p. 900-11
    [PMID:17722694]
  12. Gong W, et al.
    The development of protein microarrays and their applications in DNA-protein and protein-protein interaction analyses of Arabidopsis transcription factors.
    Mol Plant, 2008. 1(1): p. 27-41
    [PMID:19802365]
  13. Ou B, et al.
    A high-throughput screening system for Arabidopsis transcription factors and its application to Med25-dependent transcriptional regulation.
    Mol Plant, 2011. 4(3): p. 546-55
    [PMID:21343311]
  14. Tiwari SB, et al.
    The EDLL motif: a potent plant transcriptional activation domain from AP2/ERF transcription factors.
    Plant J., 2012. 70(5): p. 855-65
    [PMID:22321262]
  15. Zhang Z,Wang J,Zhang R,Huang R
    The ethylene response factor AtERF98 enhances tolerance to salt through the transcriptional activation of ascorbic acid synthesis in Arabidopsis.
    Plant J., 2012. 71(2): p. 273-87
    [PMID:22417285]

  16. MEDIATOR25 acts as an integrative hub for the regulation of jasmonate-responsive gene expression in Arabidopsis.
    Plant Physiol., 2012. 160(1): p. 541-55
    [PMID:22822211]
  17. Wang J,Zhang Z,Huang R
    Regulation of ascorbic acid synthesis in plants.
    Plant Signal Behav, 2013. 8(6): p. e24536
    [PMID:23603957]
  18. Van den Broeck L, et al.
    From network to phenotype: the dynamic wiring of an Arabidopsis transcriptional network induced by osmotic stress.
    Mol. Syst. Biol., 2017. 13(12): p. 961
    [PMID:29269383]
  19. Riechmann JL,Meyerowitz EM
    The AP2/EREBP family of plant transcription factors.
    Biol. Chem., 1998. 379(6): p. 633-46
    [PMID:9687012]