PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT3G20310.1
Common NameATERF7, ATERF-7, ERF083, ERF7, ERF-7, MQC12.5
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family ERF
Protein Properties Length: 244aa    MW: 26508.8 Da    PI: 9.0468
Description ethylene response factor 7
Gene Model
Gene Model ID Type Source Coding Sequence
AT3G20310.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP257.72.8e-182575155
          AP2  1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55
                 ++y+GVr ++ +gr++AeIrdp +   + r++lg+f++a +Aa+a++ a+++l+g
  AT3G20310.1 25 PRYRGVRKRP-WGRFAAEIRDPLK---KSRVWLGTFDSAVDAARAYDTAARNLRG 75
                 68********.**********743...5*************************99 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF008472.5E-112575IPR001471AP2/ERF domain
CDDcd000181.50E-302585No hitNo description
PROSITE profilePS5103222.9852683IPR001471AP2/ERF domain
SuperFamilySSF541712.42E-212685IPR016177DNA-binding domain
Gene3DG3DSA:3.30.730.101.6E-312683IPR001471AP2/ERF domain
SMARTSM003801.2E-372689IPR001471AP2/ERF domain
PRINTSPR003671.1E-92738IPR001471AP2/ERF domain
PRINTSPR003671.1E-94965IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006952Biological Processdefense response
GO:0009414Biological Processresponse to water deprivation
GO:0009737Biological Processresponse to abscisic acid
GO:0009873Biological Processethylene-activated signaling pathway
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005515Molecular Functionprotein binding
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009001anatomyfruit
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0009062anatomygynoecium
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025195anatomypollen tube cell
PO:0025281anatomypollen
PO:0001016developmental stageL mature pollen stage
PO:0001017developmental stageM germinated pollen stage
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 244 aa     Download sequence    Send to blast
MRKGRGSSVV GPALPVTAGG SVKEPRYRGV RKRPWGRFAA EIRDPLKKSR VWLGTFDSAV  60
DAARAYDTAA RNLRGPKAKT NFPIDCSPSS PLQPLTYLHN QNLCSPPVIQ NQIDPFMDHR  120
LYGGGNFQEQ QQQQIISRPA SSSMSSTVKS CSGPRPMEAA AASSSVAKPL HAIKRYPRTP  180
PVAPEDCHSD CDSSSSVIDD GDDIASSSSR RKTPFQFDLN FPPLDGVDLF AGGIDDLHCT  240
DLRL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gcc_A2e-202784361ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
2gcc_A2e-202384264ATERF1
3gcc_A2e-202384264ATERF1
5wx9_A6e-201992781Ethylene-responsive transcription factor ERF096
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.201610.0floral meristem| flower| vegetative tissue
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO143351490.0
Genevisible257675_at0.0
Expression AtlasAT3G20310-
AtGenExpressAT3G20310-
ATTED-IIAT3G20310-
Functional Description ? help Back to Top
Source Description
TAIREncodes a member of the ERF (ethylene response factor) subfamily B-1 of ERF/AP2 transcription factor family (ATERF-7). The protein contains one AP2 domain. Phosphorylated by PKS3 in vitro. Involved in ABA-mediated responses. Acts as a repressor of GCC boxmediated transcription together with AtSin3 and HDA19.
UniProtInvolved in the regulation of gene expression by abscisic acid, stress factors and by components of stress signal transduction pathways. Transcription factor that binds to the GCC-box pathogenesis-related promoter element. Part of a transcriptional repressor complex including a histone deacetylase. {ECO:0000269|PubMed:11487705, ECO:0000269|PubMed:15994908}.
Function -- GeneRIF ? help Back to Top
  1. Studies indicate that ethylene response factor 7 (ERF-VIIs) are directly regulated by oxygen, in that their protein half-life is determined by an oxygen-dependent mechanism of proteasomal degradation [Review].
    [PMID: 29269576]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00366DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT3G20310.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT5G44420(R)
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDabscisic acid, ethylene
Interaction ? help Back to Top
Source Intact With
IntActSearch Q9LDE4
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT3G20310
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0240360.0AB024036.1 Arabidopsis thaliana genomic DNA, chromosome 3, P1 clone: MQC12.
GenBankAB0322010.0AB032201.1 Arabidopsis thaliana mRNA for ERF transcription factor 7, complete cds.
GenBankAK2284600.0AK228460.1 Arabidopsis thaliana mRNA for putative ethylene responsive element binding factor, complete cds, clone: RAFL15-05-J12.
GenBankAY0372540.0AY037254.1 Arabidopsis thaliana AT3g20310/MQC12_6 mRNA, complete cds.
GenBankAY0940010.0AY094001.1 Arabidopsis thaliana AT3g20310/MQC12_6 mRNA, complete cds.
GenBankCP0026860.0CP002686.1 Arabidopsis thaliana chromosome 3, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_188666.11e-180ethylene response factor 7
SwissprotQ9LDE40.0ERF83_ARATH; Ethylene-responsive transcription factor 7
TrEMBLA0A178VH381e-179A0A178VH38_ARATH; ERF7
STRINGAT3G20310.11e-179(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM10281650
Representative plantOGRP6161718
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Ohta M,Matsui K,Hiratsu K,Shinshi H,Ohme-Takagi M
    Repression domains of class II ERF transcriptional repressors share an essential motif for active repression.
    Plant Cell, 2001. 13(8): p. 1959-68
    [PMID:11487705]
  3. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  4. Cluis CP,Mouchel CF,Hardtke CS
    The Arabidopsis transcription factor HY5 integrates light and hormone signaling pathways.
    Plant J., 2004. 38(2): p. 332-47
    [PMID:15078335]
  5. Song CP, et al.
    Role of an Arabidopsis AP2/EREBP-type transcriptional repressor in abscisic acid and drought stress responses.
    Plant Cell, 2005. 17(8): p. 2384-96
    [PMID:15994908]
  6. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  7. Babula D, et al.
    Genes involved in biosynthesis and signalisation of ethylene in Brassica oleracea and Arabidopsis thaliana: identification and genome comparative mapping of specific gene homologues.
    Theor. Appl. Genet., 2006. 112(3): p. 410-20
    [PMID:16311726]
  8. Nakano T,Suzuki K,Fujimura T,Shinshi H
    Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
    Plant Physiol., 2006. 140(2): p. 411-32
    [PMID:16407444]
  9. Nemhauser JL,Hong F,Chory J
    Different plant hormones regulate similar processes through largely nonoverlapping transcriptional responses.
    Cell, 2006. 126(3): p. 467-75
    [PMID:16901781]
  10. Jung J, et al.
    The barley ERF-type transcription factor HvRAF confers enhanced pathogen resistance and salt tolerance in Arabidopsis.
    Planta, 2007. 225(3): p. 575-88
    [PMID:16937017]
  11. Manavella PA, et al.
    Cross-talk between ethylene and drought signalling pathways is mediated by the sunflower Hahb-4 transcription factor.
    Plant J., 2006. 48(1): p. 125-37
    [PMID:16972869]
  12. Galuschka C,Schindler M,B├╝low L,Hehl R
    AthaMap web tools for the analysis and identification of co-regulated genes.
    Nucleic Acids Res., 2007. 35(Database issue): p. D857-62
    [PMID:17148485]
  13. Wang Y, et al.
    Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.
    Plant Physiol., 2008. 148(3): p. 1201-11
    [PMID:18775970]
  14. Kagale S,Links MG,Rozwadowski K
    Genome-wide analysis of ethylene-responsive element binding factor-associated amphiphilic repression motif-containing transcriptional regulators in Arabidopsis.
    Plant Physiol., 2010. 152(3): p. 1109-34
    [PMID:20097792]
  15. Arabidopsis Interactome Mapping Consortium
    Evidence for network evolution in an Arabidopsis interactome map.
    Science, 2011. 333(6042): p. 601-7
    [PMID:21798944]
  16. Klopffleisch K, et al.
    Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis.
    Mol. Syst. Biol., 2011. 7: p. 532
    [PMID:21952135]
  17. Gaudinier A, et al.
    Enhanced Y1H assays for Arabidopsis.
    Nat. Methods, 2011. 8(12): p. 1053-5
    [PMID:22037706]
  18. Causier B,Ashworth M,Guo W,Davies B
    The TOPLESS interactome: a framework for gene repression in Arabidopsis.
    Plant Physiol., 2012. 158(1): p. 423-38
    [PMID:22065421]
  19. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  20. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]
  21. Giuntoli B,Perata P
    Group VII Ethylene Response Factors in Arabidopsis: Regulation and Physiological Roles.
    Plant Physiol., 2018. 176(2): p. 1143-1155
    [PMID:29269576]
  22. Riechmann JL,Meyerowitz EM
    The AP2/EREBP family of plant transcription factors.
    Biol. Chem., 1998. 379(6): p. 633-46
    [PMID:9687012]