PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT3G19860.1
Common NamebHLH121, EN138, MPN9.10
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 284aa    MW: 31867.7 Da    PI: 8.4457
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT3G19860.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH27.55.7e-09755254
                 HHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
          HLH  2 rrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54
                 +  +  rE+ RR+++N+ f eL  +l +      +K++Ka+iL+ +v+ +k+L
  AT3G19860.1  7 KSQKAGREKLRREKLNEHFVELGNVLDPE----RPKNDKATILTDTVQLLKEL 55
                 5566779******************9987....69***************998 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088813.268555IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.101.1E-12578IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474593.53E-13571IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.86E-6659No hitNo description
PfamPF000109.1E-7755IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003532.4E-61161IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001016developmental stageL mature pollen stage
PO:0001017developmental stageM germinated pollen stage
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 284 aa     Download sequence    Send to blast
MDVSARKSQK AGREKLRREK LNEHFVELGN VLDPERPKND KATILTDTVQ LLKELTSEVN  60
KLKSEYTALT DESRELTQEK NDLREEKTSL KSDIENLNLQ YQQRLRSMSP WGAAMDHTVM  120
MAPPPSFPYP MPIAMPPGSI PMHPSMPSYT YFGNQNPSMI PAPCPTYMPY MPPNTVVEQQ  180
SVHIPQNPGN RSREPRAKVS RESRSEKAED SNEVATQLEL KTPGSTSDKD TLQRPEKTKR  240
CKRNNNNNSI EESSHSSKCS SSPSVRDHSS SSSVAGGQKP DDAK
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.201670.0bud| flower| leaf| seed
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO1865102530.0
Genevisible257990_at0.0
Expression AtlasAT3G19860-
AtGenExpressAT3G19860-
ATTED-IIAT3G19860-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed constitutively in roots, leaves, stems, and flowers. {ECO:0000269|PubMed:12679534}.
Function -- GeneRIF ? help Back to Top
  1. Data indicate that the transcript levels of HAK5 and four transcriptin factor genes DDF2, JLO, bHLH121 and TFII_A were highly up-regulated in response to both -K and salt stress.
    [PMID: 23825216]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT3G19860.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Interaction ? help Back to Top
Source Intact With
IntActSearch Q9LT23
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT3G19860
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY0817030.0AY081703.1 Arabidopsis thaliana unknown protein (At3g19860) mRNA, complete cds.
GenBankAY0651070.0AY065107.1 Arabidopsis thaliana unknown protein (At3g19860; MPN9.10) mRNA, complete cds.
GenBankAK3175070.0AK317507.1 Arabidopsis thaliana AT3G19860 mRNA, complete cds, clone: RAFL25-09-J11.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_188620.10.0transcription factor bHLH121
SwissprotQ9LT230.0BH121_ARATH; Transcription factor bHLH121
TrEMBLB9DHF50.0B9DHF5_ARATH; AT3G19860 protein
STRINGAT3G19860.20.0(Arabidopsis thaliana)
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  5. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  6. Yang KY,Kim YM,Lee S,Song PS,Soh MS
    Overexpression of a mutant basic helix-loop-helix protein HFR1, HFR1-deltaN105, activates a branch pathway of light signaling in Arabidopsis.
    Plant Physiol., 2003. 133(4): p. 1630-42
    [PMID:14645731]
  7. Czechowski T,Bari RP,Stitt M,Scheible WR,Udvardi MK
    Real-time RT-PCR profiling of over 1400 Arabidopsis transcription factors: unprecedented sensitivity reveals novel root- and shoot-specific genes.
    Plant J., 2004. 38(2): p. 366-79
    [PMID:15078338]
  8. Ehlting J, et al.
    Comparative transcriptome analysis of Arabidopsis thaliana infested by diamond back moth (Plutella xylostella) larvae reveals signatures of stress response, secondary metabolism, and signalling.
    BMC Genomics, 2008. 9: p. 154
    [PMID:18400103]
  9. Long TA, et al.
    The bHLH transcription factor POPEYE regulates response to iron deficiency in Arabidopsis roots.
    Plant Cell, 2010. 22(7): p. 2219-36
    [PMID:20675571]
  10. Arabidopsis Interactome Mapping Consortium
    Evidence for network evolution in an Arabidopsis interactome map.
    Science, 2011. 333(6042): p. 601-7
    [PMID:21798944]
  11. Hong JP, et al.
    Identification and characterization of transcription factors regulating Arabidopsis HAK5.
    Plant Cell Physiol., 2013. 54(9): p. 1478-90
    [PMID:23825216]