PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT3G18550.2
Common NameAtBRC1, ATTCP18, BRC1, K24M9.4, TBL1, TCP18
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family TCP
Protein Properties Length: 429aa    MW: 49309.1 Da    PI: 7.799
Description TCP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT3G18550.2genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1TCP131.11e-401463062135
          TCP   2 agkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgt................ssssaseceaesssssas 83 
                  + ++drhski T++g RdRR+Rls+++a+++F Lqd+LGfdk+skt+eWLl+qakp+i++++ t                s +++s+           
  AT3G18550.2 146 PSRTDRHSKIKTAKGTRDRRMRLSLDVAKELFGLQDMLGFDKASKTVEWLLTQAKPEIIKIATTlshhgcfssgdeshirSMDTSSD----------- 232
                  5799************************************************************77777776666655553333333........... PP

          TCP  84 nsssg..........................kaaksaakskksqksaasalnlakesrakarararertrekmriknk 135
                                                 + ++   k+k+++ ++    +l+ke+rakar+ra+ rt ekm++k k
  AT3G18550.2 233 ----LcelasmwtvddrgsntnttetrgnkvDGRSMRGKRKRPEPRTPILKKLSKEERAKARERAKGRTMEKMMMKMK 306
                  ....1233333333333333555577778876666666888888888888*************************987 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF036341.2E-41147304IPR005333Transcription factor, TCP
PROSITE profilePS5136931.724148206IPR017887Transcription factor TCP subgroup
PROSITE profilePS513709.992283300IPR017888CYC/TB1, R domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:2000032Biological Processregulation of secondary shoot formation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000232anatomyaxillary bud meristem
PO:0004709anatomyaxillary bud
Sequence ? help Back to Top
Protein Sequence    Length: 429 aa     Download sequence    Send to blast
MNNNIFSTTT TINDDYMLFP YNDHYSSQPL LPFSPSSSIN DILIHSTSNT SNNHLDHHHQ  60
FQQPSPFSHF EFAPDCALLT SFHPENNGHD DNQTIPNDNH HPSLHFPLNN TIVEQPTEPS  120
ETINLIEDSQ RISTSQDPKM KKAKKPSRTD RHSKIKTAKG TRDRRMRLSL DVAKELFGLQ  180
DMLGFDKASK TVEWLLTQAK PEIIKIATTL SHHGCFSSGD ESHIRSMDTS SDLCELASMW  240
TVDDRGSNTN TTETRGNKVD GRSMRGKRKR PEPRTPILKK LSKEERAKAR ERAKGRTMEK  300
MMMKMKGRSQ LVKVVEEDAH DHGEIIKNNN RSQVNRSSFE MTHCEDKIEE LCKNDRFAVC  360
NEFIMNKKDH ISNESYDLVN YKPNSSFPVI NHHRSQGAAN SIEQHQFTDL HYSFGAKPRD  420
LMHNYQNMY
Expression -- Microarray ? help Back to Top
Source ID
Expression AtlasAT3G18550
AtGenExpressAT3G18550
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Detected in axillary mersitems which appears in the axils of leaves after flowering. During bud vegetative development, down-regulated in the outer layers of the meristem, but accumulates transiently in young leaf primordia. In buds bearing flowers, restricted to the provascular tissue underlying the bud. Accumulates in axillary buds, but disappears at the time of bud outgrowth. {ECO:0000269|PubMed:17307924}.
UniprotTISSUE SPECIFICITY: Expressed in unelongated axillary buds, and, to a lower extent, in axillary structures such as flowers and siliques. {ECO:0000269|PubMed:17307924, ECO:0000269|PubMed:17452340}.
Functional Description ? help Back to Top
Source Description
TAIREncodes a TCP transcription factor, closely related to teosinte branched1, arrests axillary bud development and prevents axillary bud outgrowth.
UniProtTranscription factor that prevents axillary bud outgrowth and delays early axillary bud development. Indirectly required for the auxin-induced control of apical dominance. {ECO:0000269|PubMed:17307924, ECO:0000269|PubMed:17452340}.
Function -- GeneRIF ? help Back to Top
  1. BRANCHED1 (BRC1) plays a central role in the control of axillary bud development. BRC1 acts as a local integrator of the genetic pathways controlling branch outgrowth.
    [PMID: 17307924]
  2. The Arabidopsis thaliana gene BRANCHED1 (BRC1), expressed in axillary buds, is required for branch suppression in response to shade.
    [PMID: 23524661]
  3. Data indicate that BRANCHED1 (BRC1) interacts with the florigen proteins FLOWERING LOCUS T (FT) and TWIN SISTER OF FT (TSF) but not with TERMINAL FLOWER1, a floral repressor.
    [PMID: 23613197]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT3G18550.2
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced during environmentally induced bud dormancy (planting density). Repressed transiently after shoot apical meristem (SAM) decapitation (release from apical dominance). {ECO:0000269|PubMed:17307924}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Interaction ? help Back to Top
Source Intact With
BioGRIDAT4G27330
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT3G18550
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAM4085600.0AM408560.1 Arabidopsis thaliana mRNA for BRANCHED1 (brc1 gene).
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001118656.10.0transcription factor TCP18
SwissprotA1YKT10.0TCP18_ARATH; Transcription factor TCP18
TrEMBLD7L8J40.0D7L8J4_ARALL; Putative uncharacterized protein
STRINGAT3G18550.10.0(Arabidopsis thaliana)
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Damerval C,Le Guilloux M,Jager M,Charon C
    Diversity and evolution of CYCLOIDEA-like TCP genes in relation to flower development in Papaveraceae.
    Plant Physiol., 2007. 143(2): p. 759-72
    [PMID:17189327]
  3. Aguilar-Martínez JA,Poza-Carrión C,Cubas P
    Arabidopsis BRANCHED1 acts as an integrator of branching signals within axillary buds.
    Plant Cell, 2007. 19(2): p. 458-72
    [PMID:17307924]
  4. Finlayson SA
    Arabidopsis Teosinte Branched1-like 1 regulates axillary bud outgrowth and is homologous to monocot Teosinte Branched1.
    Plant Cell Physiol., 2007. 48(5): p. 667-77
    [PMID:17452340]
  5. Poza-Carri
    Role of TCP Gene BRANCHED1 in the Control of Shoot Branching in Arabidopsis.
    Plant Signal Behav, 2007. 2(6): p. 551-2
    [PMID:19704556]
  6. Finlayson SA,Krishnareddy SR,Kebrom TH,Casal JJ
    Phytochrome regulation of branching in Arabidopsis.
    Plant Physiol., 2010. 152(4): p. 1914-27
    [PMID:20154098]
  7. Mart
    Role of tomato BRANCHED1-like genes in the control of shoot branching.
    Plant J., 2011. 67(4): p. 701-14
    [PMID:21554455]
  8. Su H,Abernathy SD,White RH,Finlayson SA
    Photosynthetic photon flux density and phytochrome B interact to regulate branching in Arabidopsis.
    Plant Cell Environ., 2011. 34(11): p. 1986-98
    [PMID:21726239]
  9. Braun N, et al.
    The pea TCP transcription factor PsBRC1 acts downstream of Strigolactones to control shoot branching.
    Plant Physiol., 2012. 158(1): p. 225-38
    [PMID:22045922]
  10. Yang X, et al.
    Evolution of double positive autoregulatory feedback loops in CYCLOIDEA2 clade genes is associated with the origin of floral zygomorphy.
    Plant Cell, 2012. 24(5): p. 1834-47
    [PMID:22649271]
  11. Gonz
    BRANCHED1 promotes axillary bud dormancy in response to shade in Arabidopsis.
    Plant Cell, 2013. 25(3): p. 834-50
    [PMID:23524661]
  12. Niwa M, et al.
    BRANCHED1 interacts with FLOWERING LOCUS T to repress the floral transition of the axillary meristems in Arabidopsis.
    Plant Cell, 2013. 25(4): p. 1228-42
    [PMID:23613197]
  13. Chen X, et al.
    Roles of DgBRC1 in regulation of lateral branching in chrysanthemum (Dendranthema
    PLoS ONE, 2013. 8(4): p. e61717
    [PMID:23613914]
  14. Wei B, et al.
    The molecular mechanism of sporocyteless/nozzle in controlling Arabidopsis ovule development.
    Cell Res., 2015. 25(1): p. 121-34
    [PMID:25378179]