PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT2G47190.1
Common NameATMYB2, MYB2
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family MYB
Protein Properties Length: 273aa    MW: 31447.8 Da    PI: 5.1993
Description myb domain protein 2
Gene Model
Gene Model ID Type Source Coding Sequence
AT2G47190.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                     +g+WT+eEd +lv+ v  +G  +W+ Iar  g++Rt+k+c++rw++yl
                     79********************************************97 PP

  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                      rg+ T eE+  +++++ ++G++ W++Ia++++ gRt++++k++w++
                      7899******************.*********.***********96 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129425.951773IPR017930Myb domain
SMARTSM007175.1E-162171IPR001005SANT/Myb domain
PfamPF002491.6E-162269IPR001005SANT/Myb domain
CDDcd001671.94E-122469No hitNo description
SMARTSM007171.1E-1374122IPR001005SANT/Myb domain
PROSITE profilePS5129418.09874124IPR017930Myb domain
PfamPF002491.8E-1375118IPR001005SANT/Myb domain
CDDcd001672.00E-1079118No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006357Biological Processregulation of transcription from RNA polymerase II promoter
GO:0009414Biological Processresponse to water deprivation
GO:0009651Biological Processresponse to salt stress
GO:0009723Biological Processresponse to ethylene
GO:0009737Biological Processresponse to abscisic acid
GO:0009751Biological Processresponse to salicylic acid
GO:0016036Biological Processcellular response to phosphate starvation
GO:0030154Biological Processcell differentiation
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0046686Biological Processresponse to cadmium ion
GO:0005634Cellular Componentnucleus
GO:0000981Molecular FunctionRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001046Molecular Functioncore promoter sequence-specific DNA binding
GO:0001135Molecular Functiontranscription factor activity, RNA polymerase II transcription factor recruiting
GO:0005516Molecular Functioncalmodulin binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000293anatomyguard cell
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 273 aa     Download sequence    Send to blast
3D Structure ? help Back to Top
PDB ID Evalue Query Start Query End Hit Start Hit End Description
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Expression -- Microarray ? help Back to Top
Source ID E-value
Expression AtlasAT2G47190-
Functional Description ? help Back to Top
Source Description
TAIREncodes a MYB transcription factor that possesses an R2R3 MYB DNA binding domain and is known to regulate the expression of salt- and dehydration-responsive genes. Has been shown to bind calmodulin.
Function -- GeneRIF ? help Back to Top
  1. a specific CaM isoform mediates salt-induced Ca2+ signaling through the activation of an MYB transcriptional activator, thereby resulting in salt tolerance in plants.
    [PMID: 15569682]
  2. MYB2 is involved in iron translocation from roots to shoots.
    [PMID: 17031393]
  3. Results demonstrate that the DNA-binding domain of AtMYB2 is inhibited by S-nitrosylation of Cys53 as a consequence of nitric oxide action.
    [PMID: 17686455]
  4. An AtMYB2-regulated post apical dominance mechanism by which Arabidopsis (Arabidopsis thaliana) inhibits the outgrowth of axillary buds as part of the whole plant senescence program, is reported.
    [PMID: 21543729]
  5. The AtMYB2 transcription factor can therefore interact with the choline monooxygenase promoter directly and regulate its downstream gene expression.
    [PMID: 22714268]
  6. AtMYB2 regulates plant responses to phosphate starvation by regulating the expression of the miR399 gene.
    [PMID: 23154535]
Cis-element ? help Back to Top
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT1G77120(A), AT5G25610(A)
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDabscisic acid, ethylene, salicylic acid
Interaction ? help Back to Top
Source Intact With
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT2G47190
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK2291400.0AK229140.1 Arabidopsis thaliana mRNA for MYB transcription factor, complete cds, clone: RAFL16-42-L19.
GenBankAY5195790.0AY519579.1 Arabidopsis thaliana MYB transcription factor (At2g47190) mRNA, complete cds.
GenBankBT0109490.0BT010949.1 Arabidopsis thaliana At2g47190 gene, complete cds.
GenBankBT0116560.0BT011656.1 Arabidopsis thaliana At2g47190 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_182241.10.0myb domain protein 2
TrEMBLQ390280.0Q39028_ARATH; ATMYB2
STRINGAT2G47190.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP5171784
Publications ? help Back to Top
  1. Dennis ES, et al.
    Molecular strategies for improving waterlogging tolerance in plants.
    J. Exp. Bot., 2000. 51(342): p. 89-97
  2. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
  3. Stracke R,Werber M,Weisshaar B
    The R2R3-MYB gene family in Arabidopsis thaliana.
    Curr. Opin. Plant Biol., 2001. 4(5): p. 447-56
  4. Xiong L,Schumaker KS,Zhu JK
    Cell signaling during cold, drought, and salt stress.
    Plant Cell, 2002. 14 Suppl: p. S165-83
  5. Zheng ZL, et al.
    Plasma membrane-associated ROP10 small GTPase is a specific negative regulator of abscisic acid responses in Arabidopsis.
    Plant Cell, 2002. 14(11): p. 2787-97
  6. Abe H, et al.
    Arabidopsis AtMYC2 (bHLH) and AtMYB2 (MYB) function as transcriptional activators in abscisic acid signaling.
    Plant Cell, 2003. 15(1): p. 63-78
  7. Kamiya T,Kawabe A,Miyashita NT
    Nucleotide polymorphism at the Atmyb2 locus of the wild plant Arabidopsis thaliana.
    Genet. Res., 2002. 80(2): p. 89-98
  8. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
  9. Bae MS,Cho EJ,Choi EY,Park OK
    Analysis of the Arabidopsis nuclear proteome and its response to cold stress.
    Plant J., 2003. 36(5): p. 652-63
  10. Villalobos MA,Bartels D,Iturriaga G
    Stress tolerance and glucose insensitive phenotypes in Arabidopsis overexpressing the CpMYB10 transcription factor gene.
    Plant Physiol., 2004. 135(1): p. 309-24
  11. Lorenzo O,Chico JM,S
    JASMONATE-INSENSITIVE1 encodes a MYC transcription factor essential to discriminate between different jasmonate-regulated defense responses in Arabidopsis.
    Plant Cell, 2004. 16(7): p. 1938-50
  12. Wang S, et al.
    Control of plant trichome development by a cotton fiber MYB gene.
    Plant Cell, 2004. 16(9): p. 2323-34
  13. Anderson JP, et al.
    Antagonistic interaction between abscisic acid and jasmonate-ethylene signaling pathways modulates defense gene expression and disease resistance in Arabidopsis.
    Plant Cell, 2004. 16(12): p. 3460-79
  14. Sell S,Hehl R
    Functional dissection of a small anaerobically induced bZIP transcription factor from tomato.
    Eur. J. Biochem., 2004. 271(22): p. 4534-44
  15. Yoo JH, et al.
    Direct interaction of a divergent CaM isoform and the transcription factor, MYB2, enhances salt tolerance in arabidopsis.
    J. Biol. Chem., 2005. 280(5): p. 3697-706
  16. Mohanty B,Krishnan SP,Swarup S,Bajic VB
    Detection and preliminary analysis of motifs in promoters of anaerobically induced genes of different plant species.
    Ann. Bot., 2005. 96(4): p. 669-81
  17. Xin Z,Zhao Y,Zheng ZL
    Transcriptome analysis reveals specific modulation of abscisic acid signaling by ROP10 small GTPase in Arabidopsis.
    Plant Physiol., 2005. 139(3): p. 1350-65
  18. Yanhui C, et al.
    The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.
    Plant Mol. Biol., 2006. 60(1): p. 107-24
  19. Chen YH,Wu XM,Ling HQ,Yang WC
    Transgenic expression of DwMYB2 impairs iron transport from root to shoot in Arabidopsis thaliana.
    Cell Res., 2006. 16(10): p. 830-40
  20. Shinozaki K,Yamaguchi-Shinozaki K
    Gene networks involved in drought stress response and tolerance.
    J. Exp. Bot., 2007. 58(2): p. 221-7
  21. Serpa V, et al.
    Inhibition of AtMYB2 DNA-binding by nitric oxide involves cysteine S-nitrosylation.
    Biochem. Biophys. Res. Commun., 2007. 361(4): p. 1048-53
  22. Papdi C, et al.
    Functional identification of Arabidopsis stress regulatory genes using the controlled cDNA overexpression system.
    Plant Physiol., 2008. 147(2): p. 528-42
  23. Shangguan XX,Xu B,Yu ZX,Wang LJ,Chen XY
    Promoter of a cotton fibre MYB gene functional in trichomes of Arabidopsis and glandular trichomes of tobacco.
    J. Exp. Bot., 2008. 59(13): p. 3533-42
  24. Guo Y,Gan S
    AtMYB2 regulates whole plant senescence by inhibiting cytokinin-mediated branching at late stages of development in Arabidopsis.
    Plant Physiol., 2011. 156(3): p. 1612-9
  25. Rushton DL, et al.
    WRKY transcription factors: key components in abscisic acid signalling.
    Plant Biotechnol. J., 2012. 10(1): p. 2-11
  26. Yu L, et al.
    AtMYB2 transcription factor can interact with the CMO promoter and regulate its downstream gene expression.
    Biotechnol. Lett., 2012. 34(9): p. 1749-55
  27. Baek D, et al.
    Regulation of miR399f transcription by AtMYB2 affects phosphate starvation responses in Arabidopsis.
    Plant Physiol., 2013. 161(1): p. 362-73
  28. Baek D,Park HC,Kim MC,Yun DJ
    The role of Arabidopsis MYB2 in miR399f-mediated phosphate-starvation response.
    Plant Signal Behav, 2013. 8(3): p. e23488
  29. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
  30. Urao T,Yamaguchi-Shinozaki K,Urao S,Shinozaki K
    An Arabidopsis myb homolog is induced by dehydration stress and its gene product binds to the conserved MYB recognition sequence.
    Plant Cell, 1993. 5(11): p. 1529-39
  31. Urao T,Noji M,Yamaguchi-Shinozaki K,Shinozaki K
    A transcriptional activation domain of ATMYB2, a drought-inducible Arabidopsis Myb-related protein.
    Plant J., 1996. 10(6): p. 1145-8
  32. Abe H, et al.
    Role of arabidopsis MYC and MYB homologs in drought- and abscisic acid-regulated gene expression.
    Plant Cell, 1997. 9(10): p. 1859-68
  33. Hoeren FU,Dolferus R,Wu Y,Peacock WJ,Dennis ES
    Evidence for a role for AtMYB2 in the induction of the Arabidopsis alcohol dehydrogenase gene (ADH1) by low oxygen.
    Genetics, 1998. 149(2): p. 479-90