PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT2G46830.1
Common NameAtCCA1, CCA1, F19D11
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family MYB_related
Protein Properties Length: 608aa    MW: 66975.6 Da    PI: 5.8919
Description circadian clock associated 1
Gene Model
Gene Model ID Type Source Coding Sequence
AT2G46830.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47
                     r rWT+eE+ ++++a +++G   W +I +++  ++t+ q++s+ qk+
                     78******************88.*********.************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129421.271973IPR017930Myb domain
TIGRFAMsTIGR015571.2E-162271IPR006447Myb domain, plants
SMARTSM007171.0E-122371IPR001005SANT/Myb domain
PfamPF002491.3E-122467IPR001005SANT/Myb domain
CDDcd001671.81E-92669No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009409Biological Processresponse to cold
GO:0009651Biological Processresponse to salt stress
GO:0009723Biological Processresponse to ethylene
GO:0009733Biological Processresponse to auxin
GO:0009737Biological Processresponse to abscisic acid
GO:0009739Biological Processresponse to gibberellin
GO:0009751Biological Processresponse to salicylic acid
GO:0009753Biological Processresponse to jasmonic acid
GO:0010243Biological Processresponse to organonitrogen compound
GO:0042754Biological Processnegative regulation of circadian rhythm
GO:0043496Biological Processregulation of protein homodimerization activity
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0046686Biological Processresponse to cadmium ion
GO:0048574Biological Processlong-day photoperiodism, flowering
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005515Molecular Functionprotein binding
GO:0019904Molecular Functionprotein domain specific binding
GO:0043565Molecular Functionsequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000003anatomywhole plant
PO:0000013anatomycauline leaf
PO:0000014anatomyrosette leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009025anatomyvascular leaf
PO:0009052anatomyflower pedicel
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007131developmental stageseedling development stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 608 aa     Download sequence    Send to blast
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.109560.0vegetative tissue
Expression -- Microarray ? help Back to Top
Source ID E-value
Expression AtlasAT2G46830-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in leaves, roots, stems, flowers and siliques. {ECO:0000269|PubMed:19095940, ECO:0000269|PubMed:19218364}.
Functional Description ? help Back to Top
Source Description
TAIREncodes a transcriptional repressor that performs overlapping functions with LHY in a regulatory feedback loop that is closely associated with the circadian oscillator of Arabidopsis. Binds to the evening element in the promoter of TOC1 and represses TOC1 transcription. CCA1 and LHY colocalize in the nucleus and form heterodimers in vivo. CCA1 and LHY function synergistically in regulating circadian rhythms of Arabidopsis.
UniProtTranscription factor involved in the circadian clock and in the phytochrome regulation. Binds to the promoter regions of APRR1/TOC1 and TCP21/CHE to repress their transcription. Binds to the promoter regions of CAB2A and CAB2B to promote their transcription. Represses both LHY and itself. {ECO:0000269|PubMed:11486091, ECO:0000269|PubMed:12007421, ECO:0000269|PubMed:12015970, ECO:0000269|PubMed:19095940, ECO:0000269|PubMed:19218364, ECO:0000269|PubMed:19339503, ECO:0000269|PubMed:9657153}.
Function -- GeneRIF ? help Back to Top
  1. This study demonstrated a light-entrained circadian clock regulates ethylene release from unstressed, wild-type Arabidopsis (Arabidopsis thaliana) seedlings, with a peak in the mid-subjective day.
    [PMID: 15516515]
  2. A functional interaction between the CCA1 clock component and one of the PRR family members, PRR5, by employing transgenic lines overexpressing both the CCA1 and PRR5 genes is reported.
    [PMID: 15725674]
  3. The function of ELF3 and ELF4 in their light-regulated expression associated with CCA1, LHY, and TOC1 as part of the central oscillator of the circadian clock in Arabidopsis is reported.
    [PMID: 16212608]
  4. TOC1 regulates the floral transition in a CCA1/LHY-dependent manner while CCA1/LHY functions upstream of TOC1 in regulating a photomorphogenic process.
    [PMID: 17483414]
  5. The linkages of TOC1, CCA1 and LHY genes and the canonical CO-FT flowering pathway were studied.
    [PMID: 17540692]
  6. This study suggests that the combination of light regulation of CCA1 transcription and CCA1 messenger RNA degradation is important for ensuring that the Arabidopsis circadian oscillator is accurately entrained by environmental changes.
    [PMID: 17873091]
  7. Regulation of CCA1 by organic N signals may represent a novel input mechanism for N-nutrients to affect plant circadian clock function.
    [PMID: 18344319]
  8. data suggests that CCA1 acts predominantly as a transcriptional repressor in nature
    [PMID: 18460819]
  9. CCA1 and LHY delay flowering time under continuous light by reducing the accumulation of SVP.
    [PMID: 19011118]
  10. CCA1 and LHY function synergistically in regulating circadian rhythms of Arabidopsis.
    [PMID: 19218364]
  11. CCA1 is localized to the nucleus in vivo and that there is no significant delay between the translation of CCA1 and its translocation to the nucleus.
    [PMID: 19339503]
  12. LHY/CCA1 regulates a pathway negatively controlling flowering locus T (FT), possibly via ELF3-SVP/FLC.
    [PMID: 19383102]
  13. Expression of CCA1 is regulated in part by a regulatory element within the 5'UTR.
    [PMID: 20119844]
  14. This study establishes a new model demonstrating that two opposing and temperature-dependent activities (CCA1-CK2) are essential for clock temperature compensation in Arabidopsis.
    [PMID: 21079791]
  15. Results reveal a role of PRR7 and PRR9 in regulating CCA1 and LHY activities in response to ambient temperature.
    [PMID: 21098730]
  16. role in circadian oscillatory regulation of chloroplastic thioredoxins f and m
    [PMID: 21196476]
  17. defence genes are under circadian control by CCA1, allowing plants to 'anticipate' infection at dawn when the pathogen normally disperses the spores and time immune responses according to the perception of different pathogenic signals upon infection
    [PMID: 21293378]
  18. CCA1 interacts with the BOA promoter and regulates its expression.
    [PMID: 21447790]
  19. CCA1/LHY-mediated output from the circadian clock contributes to plant cold tolerance through regulation of the CBF cold-response pathway.
    [PMID: 21471455]
  20. Functional interactions between the clock proteins LHY and CCA1 and the photoreceptor PhyB control organ elongation and flowering time.
    [PMID: 21822060]
  21. Interaction of Arabidopsis DET1 with CCA1 in mediating transcriptional repression in the plant circadian clock.
    [PMID: 21884973]
  22. show that CCA1 represses ELF3 by associating with its promoter, completing a CCA1-ELF3 negative feedback loop that places ELF3 within the oscillator
    [PMID: 22190341]
  23. Our computational analysis suggests that TOC1 is a repressor of the morning genes Late Elongated Hypocotyl and Circadian Clock Associated1 rather than an activator as first conceived.
    [PMID: 22395476]
  24. dynamic self-regulation of CCA1 underlies the circadian clock regulation of temperature responses in Arabidopsis
    [PMID: 22715042]
  25. Rhythmic expression of CCA1 under light-dark cycling conditions correlates with histone modification.
    [PMID: 22878891]
  26. CCA1 activity is self-regulated by a splice variant CCA1beta and the CCA1beta production is modulated by low temperatures, linking the circadian clock with cold acclimation.
    [PMID: 22899064]
  27. We propose CCA1 as a master regulator of Reactive-Oxygen-Species homeostasis through association with the Evening Element in promoters of ROS genes in vivo to coordinate time-dependent responses to oxidative stress.
    [PMID: 23027948]
  28. Histone 3 activating marks associated with the translational start sites of CCA1/LHY and TOC1 are circadian regulated.
    [PMID: 23128602]
  29. the promoter activity of A. thaliana core clock genes CCA1 and PRR5 in heterologous L. japonicus cells
    [PMID: 23221703]
  30. Transcriptional co-regulators PRR9, PRR7 and PRR5 inhibit circadian clock morning loop CCA1 expression by binding to its promoter.
    [PMID: 24267177]
  31. work revealed several CCA1 targets that do not cycle in either LL or LD conditions. Together, our results emphasize an expanded role for the clock in regulating a diverse category of genes and key pathways in Arabidopsis
    [PMID: 26261339]
  32. Results show that TOC1 and CCA1 mRNA transcription levels are regulated by the newly identified Hesp gene and suggest a deadenylation as a mechanism involved in the regulation of the circadian clock. [hesp]
    [PMID: 26619288]
  33. the diurnal changes of endogenous melatonin may regulate corresponding changes of AtCBF/DREB1s expression and their underlying diurnal cycle of plant immunity and AtCCA1.
    [PMID: 26828406]
  34. Direct binding by CCA1 in the morning provides strong repression of PRR5, and repression by CCA1 also temporally regulates an evening-expressed gene set that includes PRR5.
    [PMID: 26941090]
  35. Data show that binding of LWD1 and TEOSINTE BRANCHED 1-CYCLOIDEA-PCF20 (TCP20) and TCP22 to the TCP-binding site in the CIRCADIAN CLOCK ASSOCIATED1 (CCA1) promoter activates CCA1.
    [PMID: 27734958]
  36. These results show that the guard cell oscillator is different from the average plant oscillator, and that the differences in guard cell oscillator function may be important for the correct regulation of photoperiod pathway genes that have previously been reported to control stomatal aperture.
    [PMID: 29084902]
  37. undergoes dynamic sumoylation, which directly alters the binding affinity to the evening element
    [PMID: 29172852]
  38. MLK1/2 and RGA directly interact with CIRCADIAN CLOCK ASSOCIATED1 (CCA1), which targets the promoter of DWARF4 (DWF4) to regulate its roles in cell expansion.
    [PMID: 29255112]
  39. The study suggests that CSU4 acts as a negative regulator of CCA1 via physically associating with CCA1, which in turn, likely serves to repress expression of CCA1 and PIF4 to promote photomorphogenesis.
    [PMID: 30352855]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
Motif logo
Cis-element ? help Back to Top
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Circadian-regulation with peak levels occurring around 1 hour after dawn. Up-regulated by APRR1/TOC1 and transiently by light treatment. Down-regulated by APRR5, APRR7 and APRR9. The CCA1 mRNA is relatively stable in the dark and in far-red light but has a short half-life in red and blue light. {ECO:0000269|PubMed:17873091, ECO:0000269|PubMed:19095940, ECO:0000269|PubMed:19218364, ECO:0000269|PubMed:19286557, ECO:0000269|PubMed:20233950, ECO:0000269|PubMed:9144958, ECO:0000269|PubMed:9657153}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
Regulation -- ATRM (Manually Curated Upstream Regulators) ? help Back to Top
Source Upstream Regulator (A: Activate/R: Repress)
ATRM AT1G09530 (A), AT3G46640 (A), AT5G37260 (R), AT5G59570 (A)
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT1G01060(R), AT1G04400(A), AT1G22770(R), AT1G29930(A), AT1G32900(A), AT1G65480(A), AT2G21660(R), AT2G40080(R), AT2G43010(A), AT2G46790(A), AT3G17820(A), AT3G46640(R), AT3G47340(R), AT3G59060(A), AT5G02810(A), AT5G15840(R), AT5G18170(R), AT5G49450(R), AT5G52310(R), AT5G57360(R), AT5G61380(R)
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDabscisic acid, auxin, ethylene, gibberellin, Gibberellin, jasmonic acid, salicylic acid
Interaction ? help Back to Top
Source Intact With
BioGRIDAT2G46830, AT3G22170, AT4G18390, AT5G11260, AT1G01060
IntActSearch P92973
Phenotype -- Disruption Phenotype ? help Back to Top
Source Description
UniProtDISRUPTION PHENOTYPE: Altered phytochrome regulation and shorter circadian oscillations. {ECO:0000269|PubMed:10097183, ECO:0000269|PubMed:19218364}.
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT2G46830
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankATU284220.0U28422.1 Arabidopsis thaliana DNA-binding protein CCA1 (CCA1) mRNA, complete cds.
GenBankAY5195110.0AY519511.1 Arabidopsis thaliana MYB transcription factor (At2g46830) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_850460.10.0circadian clock associated 1
SwissprotP929730.0CCA1_ARATH; Protein CCA1
STRINGAT2G46830.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP9903510
Publications ? help Back to Top
  1. Staiger D,Heintzen C
    The circadian system of Arabidopsis thaliana: forward and reverse genetic approaches.
    Chronobiol. Int., 1999. 16(1): p. 1-16
  2. Green RM,Tobin EM
    Loss of the circadian clock-associated protein 1 in Arabidopsis results in altered clock-regulated gene expression.
    Proc. Natl. Acad. Sci. U.S.A., 1999. 96(7): p. 4176-9
  3. Fowler S, et al.
    GIGANTEA: a circadian clock-controlled gene that regulates photoperiodic flowering in Arabidopsis and encodes a protein with several possible membrane-spanning domains.
    EMBO J., 1999. 18(17): p. 4679-88
  4. Park DH, et al.
    Control of circadian rhythms and photoperiodic flowering by the Arabidopsis GIGANTEA gene.
    Science, 1999. 285(5433): p. 1579-82
  5. Somers DE
    The physiology and molecular bases of the plant circadian clock.
    Plant Physiol., 1999. 121(1): p. 9-20
  6. Sugano S,Andronis C,Ong MS,Green RM,Tobin EM
    The protein kinase CK2 is involved in regulation of circadian rhythms in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 1999. 96(22): p. 12362-6
  7. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
  8. Schaffer R, et al.
    Microarray analysis of diurnal and circadian-regulated genes in Arabidopsis.
    Plant Cell, 2001. 13(1): p. 113-23
  9. Xu Y,Johnson CH
    A clock- and light-regulated gene that links the circadian oscillator to LHCB gene expression.
    Plant Cell, 2001. 13(6): p. 1411-25
  10. Alabadí D, et al.
    Reciprocal regulation between TOC1 and LHY/CCA1 within the Arabidopsis circadian clock.
    Science, 2001. 293(5531): p. 880-3
  11. Makino S,Matsushika A,Kojima M,Yamashino T,Mizuno T
    The APRR1/TOC1 quintet implicated in circadian rhythms of Arabidopsis thaliana: I. Characterization with APRR1-overexpressing plants.
    Plant Cell Physiol., 2002. 43(1): p. 58-69
  12. Alabad
    Critical role for CCA1 and LHY in maintaining circadian rhythmicity in Arabidopsis.
    Curr. Biol., 2002. 12(9): p. 757-61
  13. Mizoguchi T, et al.
    LHY and CCA1 are partially redundant genes required to maintain circadian rhythms in Arabidopsis.
    Dev. Cell, 2002. 2(5): p. 629-41
  14. Yoshida I,Yamagata H,Hirasawa E
    Signal transduction controlling the blue- and red-light mediated gene expression of S-adenosylmethionine decarboxylase in Pharbitis nil.
    J. Exp. Bot., 2002. 53(373): p. 1525-9
  15. Green RM,Tingay S,Wang ZY,Tobin EM
    Circadian rhythms confer a higher level of fitness to Arabidopsis plants.
    Plant Physiol., 2002. 129(2): p. 576-84
  16. Devlin PF
    Signs of the time: environmental input to the circadian clock.
    J. Exp. Bot., 2002. 53(374): p. 1535-50
  17. Carr
    MYB transcription factors in the Arabidopsis circadian clock.
    J. Exp. Bot., 2002. 53(374): p. 1551-7
  18. Kircher S, et al.
    Nucleocytoplasmic partitioning of the plant photoreceptors phytochrome A, B, C, D, and E is regulated differentially by light and exhibits a diurnal rhythm.
    Plant Cell, 2002. 14(7): p. 1541-55
  19. Matsushika A,Imamura A,Yamashino T,Mizuno T
    Aberrant expression of the light-inducible and circadian-regulated APRR9 gene belonging to the circadian-associated APRR1/TOC1 quintet results in the phenotype of early flowering in Arabidopsis thaliana.
    Plant Cell Physiol., 2002. 43(8): p. 833-43
  20. Doyle MR, et al.
    The ELF4 gene controls circadian rhythms and flowering time in Arabidopsis thaliana.
    Nature, 2002. 419(6902): p. 74-7
  21. Michael TP,McClung CR
    Phase-specific circadian clock regulatory elements in Arabidopsis.
    Plant Physiol., 2002. 130(2): p. 627-38
  22. Hall A,Kozma-Bogn
    Distinct regulation of CAB and PHYB gene expression by similar circadian clocks.
    Plant J., 2002. 32(4): p. 529-37
  23. Sato E,Nakamichi N,Yamashino T,Mizuno T
    Aberrant expression of the Arabidopsis circadian-regulated APRR5 gene belonging to the APRR1/TOC1 quintet results in early flowering and hypersensitiveness to light in early photomorphogenesis.
    Plant Cell Physiol., 2002. 43(11): p. 1374-85
  24. M
    Dual role of TOC1 in the control of circadian and photomorphogenic responses in Arabidopsis.
    Plant Cell, 2003. 15(1): p. 223-36
  25. Staiger D, et al.
    The Arabidopsis SRR1 gene mediates phyB signaling and is required for normal circadian clock function.
    Genes Dev., 2003. 17(2): p. 256-68
  26. Kim JY,Song HR,Taylor BL,Carr
    Light-regulated translation mediates gated induction of the Arabidopsis clock protein LHY.
    EMBO J., 2003. 22(4): p. 935-44
  27. Nakamichi N,Matsushika A,Yamashino T,Mizuno T
    Cell autonomous circadian waves of the APRR1/TOC1 quintet in an established cell line of Arabidopsis thaliana.
    Plant Cell Physiol., 2003. 44(3): p. 360-5
  28. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
  29. Tenorio G,Orea A,Romero JM,M
    Oscillation of mRNA level and activity of granule-bound starch synthase I in Arabidopsis leaves during the day/night cycle.
    Plant Mol. Biol., 2003. 51(6): p. 949-58
  30. Michael TP,McClung CR
    Enhancer trapping reveals widespread circadian clock transcriptional control in Arabidopsis.
    Plant Physiol., 2003. 132(2): p. 629-39
  31. Eriksson ME,Millar AJ
    The circadian clock. A plant's best friend in a spinning world.
    Plant Physiol., 2003. 132(2): p. 732-8
  32. Eriksson ME,Hanano S,Southern MM,Hall A,Millar AJ
    Response regulator homologues have complementary, light-dependent functions in the Arabidopsis circadian clock.
    Planta, 2003. 218(1): p. 159-62
  33. Kuno N, et al.
    The novel MYB protein EARLY-PHYTOCHROME-RESPONSIVE1 is a component of a slave circadian oscillator in Arabidopsis.
    Plant Cell, 2003. 15(10): p. 2476-88
  34. Hall A, et al.
    The TIME FOR COFFEE gene maintains the amplitude and timing of Arabidopsis circadian clocks.
    Plant Cell, 2003. 15(11): p. 2719-29
  35. Maxwell BB,Andersson CR,Poole DS,Kay SA,Chory J
    HY5, Circadian Clock-Associated 1, and a cis-element, DET1 dark response element, mediate DET1 regulation of chlorophyll a/b-binding protein 2 expression.
    Plant Physiol., 2003. 133(4): p. 1565-77
  36. Kaczorowski KA,Quail PH
    Arabidopsis PSEUDO-RESPONSE REGULATOR7 is a signaling intermediate in phytochrome-regulated seedling deetiolation and phasing of the circadian clock.
    Plant Cell, 2003. 15(11): p. 2654-65
  37. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
  38. Ito S, et al.
    Characterization of the APRR9 pseudo-response regulator belonging to the APRR1/TOC1 quintet in Arabidopsis thaliana.
    Plant Cell Physiol., 2003. 44(11): p. 1237-45
  39. Oda A,Fujiwara S,Kamada H,Coupland G,Mizoguchi T
    Antisense suppression of the Arabidopsis PIF3 gene does not affect circadian rhythms but causes early flowering and increases FT expression.
    FEBS Lett., 2004. 557(1-3): p. 259-64
  40. Nakamichi N, et al.
    Characterization of plant circadian rhythms by employing Arabidopsis cultured cells with bioluminescence reporters.
    Plant Cell Physiol., 2004. 45(1): p. 57-67
  41. Daniel X,Sugano S,Tobin EM
    CK2 phosphorylation of CCA1 is necessary for its circadian oscillator function in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2004. 101(9): p. 3292-7
  42. Searle I,Coupland G
    Induction of flowering by seasonal changes in photoperiod.
    EMBO J., 2004. 23(6): p. 1217-22
  43. Yasuhara M, et al.
    Identification of ASK and clock-associated proteins as molecular partners of LKP2 (LOV kelch protein 2) in Arabidopsis.
    J. Exp. Bot., 2004. 55(405): p. 2015-27
  44. Thain SC, et al.
    Circadian rhythms of ethylene emission in Arabidopsis.
    Plant Physiol., 2004. 136(3): p. 3751-61
  45. Farré EM,Harmer SL,Harmon FG,Yanovsky MJ,Kay SA
    Overlapping and distinct roles of PRR7 and PRR9 in the Arabidopsis circadian clock.
    Curr. Biol., 2005. 15(1): p. 47-54
  46. Nakamichi N, et al.
    The Arabidopsis pseudo-response regulators, PRR5 and PRR7, coordinately play essential roles for circadian clock function.
    Plant Cell Physiol., 2005. 46(4): p. 609-19
  47. Fujimori T,Sato E,Yamashino T,Mizuno T
    PRR5 (PSEUDO-RESPONSE REGULATOR 5) plays antagonistic roles to CCA1 (CIRCADIAN CLOCK-ASSOCIATED 1) in Arabidopsis thaliana.
    Biosci. Biotechnol. Biochem., 2005. 69(2): p. 426-30
  48. Boxall SF, et al.
    Conservation and divergence of circadian clock operation in a stress-inducible Crassulacean acid metabolism species reveals clock compensation against stress.
    Plant Physiol., 2005. 137(3): p. 969-82
  49. Chang WC,Li CW,Chen BS
    Quantitative inference of dynamic regulatory pathways via microarray data.
    BMC Bioinformatics, 2005. 6: p. 44
  50. Nakamichi N,Kita M,Ito S,Yamashino T,Mizuno T
    PSEUDO-RESPONSE REGULATORS, PRR9, PRR7 and PRR5, together play essential roles close to the circadian clock of Arabidopsis thaliana.
    Plant Cell Physiol., 2005. 46(5): p. 686-98
  51. Harmer SL,Kay SA
    Positive and negative factors confer phase-specific circadian regulation of transcription in Arabidopsis.
    Plant Cell, 2005. 17(7): p. 1926-40
  52. Hazen SP, et al.
    LUX ARRHYTHMO encodes a Myb domain protein essential for circadian rhythms.
    Proc. Natl. Acad. Sci. U.S.A., 2005. 102(29): p. 10387-92
  53. Mizoguchi T, et al.
    Distinct roles of GIGANTEA in promoting flowering and regulating circadian rhythms in Arabidopsis.
    Plant Cell, 2005. 17(8): p. 2255-70
  54. Lu Y,Gehan JP,Sharkey TD
    Daylength and circadian effects on starch degradation and maltose metabolism.
    Plant Physiol., 2005. 138(4): p. 2280-91
  55. Onai K,Ishiura M
    PHYTOCLOCK 1 encoding a novel GARP protein essential for the Arabidopsis circadian clock.
    Genes Cells, 2005. 10(10): p. 963-72
  56. Kikis EA,Khanna R,Quail PH
    ELF4 is a phytochrome-regulated component of a negative-feedback loop involving the central oscillator components CCA1 and LHY.
    Plant J., 2005. 44(2): p. 300-13
  57. Salom
    Arabidopsis response regulators ARR3 and ARR4 play cytokinin-independent roles in the control of circadian period.
    Plant Cell, 2006. 18(1): p. 55-69
  58. Yanhui C, et al.
    The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.
    Plant Mol. Biol., 2006. 60(1): p. 107-24
  59. Miwa K,Serikawa M,Suzuki S,Kondo T,Oyama T
    Conserved expression profiles of circadian clock-related genes in two Lemna species showing long-day and short-day photoperiodic flowering responses.
    Plant Cell Physiol., 2006. 47(5): p. 601-12
  60. McClung CR
    Plant circadian rhythms.
    Plant Cell, 2006. 18(4): p. 792-803
  61. Gould PD, et al.
    The molecular basis of temperature compensation in the Arabidopsis circadian clock.
    Plant Cell, 2006. 18(5): p. 1177-87
  62. Ishikawa M,Kiba T,Chua NH
    The Arabidopsis SPA1 gene is required for circadian clock function and photoperiodic flowering.
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