PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT2G44840.1
Common NameATERF13, EREBP, ERF099, ERF13, ERF-13, T13E15.15
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family ERF
Protein Properties Length: 226aa    MW: 25353.1 Da    PI: 6.7937
Description ethylene-responsive element binding factor 13
Gene Model
Gene Model ID Type Source Coding Sequence
AT2G44840.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP262.31.1e-1991141255
          AP2   2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                  +y+GVr+++ +g+++AeIrdp++ng  +r++lg++ t+e+Aa a+++a+ +l+g
  AT2G44840.1  91 QYRGVRRRP-WGKFAAEIRDPKKNG--ARVWLGTYETPEDAAVAYDRAAFQLRG 141
                  59*******.***********9998..*************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5103224.10591149IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.102.3E-3291150IPR001471AP2/ERF domain
CDDcd000182.36E-3191151No hitNo description
SuperFamilySSF541712.75E-2391150IPR016177DNA-binding domain
SMARTSM003801.4E-3791155IPR001471AP2/ERF domain
PfamPF008473.3E-1392141IPR001471AP2/ERF domain
PRINTSPR003671.8E-1392103IPR001471AP2/ERF domain
PRINTSPR003671.8E-13131151IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0006952Biological Processdefense response
GO:0009873Biological Processethylene-activated signaling pathway
GO:0010200Biological Processresponse to chitin
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000037anatomyshoot apex
PO:0000293anatomyguard cell
PO:0009005anatomyroot
PO:0009009anatomyplant embryo
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0001185developmental stageplant embryo globular stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 226 aa     Download sequence    Send to blast
MSSSDSVNNG VNSRMYFRNP SFSNVILNDN WSDLPLSVDD SQDMAIYNTL RDAVSSGWTP  60
SVPPVTSPAE ENKPPATKAS GSHAPRQKGM QYRGVRRRPW GKFAAEIRDP KKNGARVWLG  120
TYETPEDAAV AYDRAAFQLR GSKAKLNFPH LIGSCKYEPV RIRPRRRSPE PSVSDQLTSE  180
QKRESHVDDG ESSLVVPELD FTVDQFYFDG SLLMDQSECS YSDNRI
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2gcc_A9e-3288154268ATERF1
3gcc_A9e-3288154268ATERF1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.290140.0leaf| root| seed
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO306898490.0
Genevisible266821_at0.0
Expression AtlasAT2G44840-
AtGenExpressAT2G44840-
ATTED-IIAT2G44840-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Ubiquitously expressed after ethylene treatment. {ECO:0000269|PubMed:11950980}.
Functional Description ? help Back to Top
Source Description
TAIRencodes a member of the ERF (ethylene response factor) subfamily B-3 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 18 members in this subfamily including ATERF-1, ATERF-2, AND ATERF-5.
UniProtActs as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. {ECO:0000269|PubMed:11950980}.
Function -- GeneRIF ? help Back to Top
  1. Data show that AtERF13 (At2g44840), one of the CEBFs, confers ABA hypersensitivity.
    [PMID: 21162722]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00311DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT2G44840.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Strongly induced by wounding. Induced by Pseudomonas syringae tomato (both virulent and avirulent avrRpt2 strains), independently of PAD4. Also induced by methyl jasmonate (MeJA) independently of JAR1, but seems to not be affected by ethylene. Induction by salicylic acid (SA) is controlled by growth and/or developmental conditions, and seems to be more efficient and independent of PAD4 in older plants. {ECO:0000269|PubMed:11950980, ECO:0000269|PubMed:12068110}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Upstream Regulators) ? help Back to Top
Source Upstream Regulator (A: Activate/R: Repress)
ATRM AT1G04370 (A)
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDethylene
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT2G44840
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC0023880.0AC002388.3 Arabidopsis thaliana chromosome 2 clone T13E15 map m336, complete sequence.
GenBankAF3250890.0AF325089.1 Arabidopsis thaliana putative ethylene response element binding protein (EREBP) (At2g44840) mRNA, complete cds.
GenBankAF3705400.0AF370540.1 Arabidopsis thaliana putative ethylene response element binding protein; EREBP (At2g44840; T13E15.15) mRNA, complete cds.
GenBankAY0724710.0AY072471.1 Arabidopsis thaliana putative ethylene response element binding protein (EREBP) (At2g44840; T13E15.15) mRNA, complete cds.
GenBankCP0026850.0CP002685.1 Arabidopsis thaliana chromosome 2, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_182011.11e-168ethylene-responsive element binding factor 13
SwissprotQ8L9K11e-169ERF99_ARATH; Ethylene-responsive transcription factor 13
TrEMBLA0A178W1M81e-166A0A178W1M8_ARATH; ERF13
STRINGAT2G44840.11e-167(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM10281650
Representative plantOGRP6161718
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. O
    Identification of Arabidopsis ethylene-responsive element binding factors with distinct induction kinetics after pathogen infection.
    Plant Physiol., 2002. 128(4): p. 1313-22
    [PMID:11950980]
  3. Cheong YH, et al.
    Transcriptional profiling reveals novel interactions between wounding, pathogen, abiotic stress, and hormonal responses in Arabidopsis.
    Plant Physiol., 2002. 129(2): p. 661-77
    [PMID:12068110]
  4. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  5. Koroleva OA,Tomlinson ML,Leader D,Shaw P,Doonan JH
    High-throughput protein localization in Arabidopsis using Agrobacterium-mediated transient expression of GFP-ORF fusions.
    Plant J., 2005. 41(1): p. 162-74
    [PMID:15610358]
  6. Babula D, et al.
    Genes involved in biosynthesis and signalisation of ethylene in Brassica oleracea and Arabidopsis thaliana: identification and genome comparative mapping of specific gene homologues.
    Theor. Appl. Genet., 2006. 112(3): p. 410-20
    [PMID:16311726]
  7. Nakano T,Suzuki K,Fujimura T,Shinshi H
    Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
    Plant Physiol., 2006. 140(2): p. 411-32
    [PMID:16407444]
  8. Libault M,Wan J,Czechowski T,Udvardi M,Stacey G
    Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-ligase genes responding to chitin, a plant-defense elicitor.
    Mol. Plant Microbe Interact., 2007. 20(8): p. 900-11
    [PMID:17722694]
  9. Welsch R,Maass D,Voegel T,Dellapenna D,Beyer P
    Transcription factor RAP2.2 and its interacting partner SINAT2: stable elements in the carotenogenesis of Arabidopsis leaves.
    Plant Physiol., 2007. 145(3): p. 1073-85
    [PMID:17873090]
  10. Maimbo M,Ohnishi K,Hikichi Y,Yoshioka H,Kiba A
    Induction of a small heat shock protein and its functional roles in Nicotiana plants in the defense response against Ralstonia solanacearum.
    Plant Physiol., 2007. 145(4): p. 1588-99
    [PMID:17965181]
  11. Lee SJ,Park JH,Lee MH,Yu JH,Kim SY
    Isolation and functional characterization of CE1 binding proteins.
    BMC Plant Biol., 2010. 10: p. 277
    [PMID:21162722]
  12. Sogabe Y, et al.
    Visualization of wounding-induced root-to-shoot communication in Arabidopsis.
    Plant Signal Behav, 2011. 6(7): p. 1037-9
    [PMID:21617378]
  13. Tiwari SB, et al.
    The EDLL motif: a potent plant transcriptional activation domain from AP2/ERF transcription factors.
    Plant J., 2012. 70(5): p. 855-65
    [PMID:22321262]
  14. Srivastava S, et al.
    Gene expression profiling through microarray analysis in Arabidopsis thaliana colonized by Pseudomonas putida MTCC5279, a plant growth promoting rhizobacterium.
    Plant Signal Behav, 2012. 7(2): p. 235-45
    [PMID:22353860]
  15. Schweizer F,Bodenhausen N,Lassueur S,Masclaux FG,Reymond P
    Differential Contribution of Transcription Factors to Arabidopsis thaliana Defense Against Spodoptera littoralis.
    Front Plant Sci, 2013. 4: p. 13
    [PMID:23382734]
  16. Kang NY,Lee HW,Kim J
    The AP2/EREBP gene PUCHI Co-Acts with LBD16/ASL18 and LBD18/ASL20 downstream of ARF7 and ARF19 to regulate lateral root development in Arabidopsis.
    Plant Cell Physiol., 2013. 54(8): p. 1326-34
    [PMID:23749813]
  17. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  18. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]
  19. Nemoto K,Takemori N,Seki M,Shinozaki K,Sawasaki T
    Members of the Plant CRK Superfamily Are Capable of Trans- and Autophosphorylation of Tyrosine Residues.
    J. Biol. Chem., 2015. 290(27): p. 16665-77
    [PMID:25969537]
  20. Riechmann JL,Meyerowitz EM
    The AP2/EREBP family of plant transcription factors.
    Biol. Chem., 1998. 379(6): p. 633-46
    [PMID:9687012]