PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT2G41130.1
Common NameBHLH106, EN56, T3K9.10
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 253aa    MW: 27977.8 Da    PI: 7.9164
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT2G41130.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH31.63e-1069115354
                  HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
          HLH   3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                  r+h+e+ErrRR+riNs +++Lr +l  +      K +Ka+ L k+v+ +++L
  AT2G41130.1  69 RNHKEAERRRRERINSHLNKLRNVLSCN-----SKTDKATLLAKVVQRVREL 115
                  58***********************997.....7************998887 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088814.44966115IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474592.22E-1269128IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000109.1E-869115IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.106.9E-1269126IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003533.2E-972121IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0042538Biological Processhyperosmotic salinity response
GO:0005634Cellular Componentnucleus
GO:0009941Cellular Componentchloroplast envelope
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000293anatomyguard cell
Sequence ? help Back to Top
Protein Sequence    Length: 253 aa     Download sequence    Send to blast
MQPETSDQML YSFLAGNEVG GGGYCVSGDY MTTMQSLCGS SSSTSSYYPL AISGIGETMA  60
QDRALAALRN HKEAERRRRE RINSHLNKLR NVLSCNSKTD KATLLAKVVQ RVRELKQQTL  120
ETSDSDQTLL PSETDEISVL HFGDYSNDGH IIFKASLCCE DRSDLLPDLM EILKSLNMKT  180
LRAEMVTIGG RTRSVLVVAA DKEMHGVESV HFLQNALKSL LERSSKSLME RSSGGGGGER  240
SKRRRALDHI IMV
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
17479ERRRRE
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO306885360.0
Expression AtlasAT2G41130-
AtGenExpressAT2G41130-
Function -- GeneRIF ? help Back to Top
  1. locates at a branching point in abiotic stress response network by interacting directly to the G-box in genes conferring salt tolerance
    [PMID: 25978450]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT2G41130.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Interaction ? help Back to Top
Source Intact With
BioGRIDAT5G11260
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT2G41130
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK1190590.0AK119059.1 Arabidopsis thaliana At2g41130 mRNA for putative bHLH transcription factor (bHLH106), complete cds, clone: RAFL21-40-D23.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_181646.10.0basic helix-loop-helix (bHLH) DNA-binding superfamily protein
SwissprotO806740.0BH106_ARATH; Transcription factor bHLH106
TrEMBLA0A178VRM60.0A0A178VRM6_ARATH; Uncharacterized protein
STRINGAT2G41130.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM36422762
Representative plantOGRP37715106
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Seki M, et al.
    Functional annotation of a full-length Arabidopsis cDNA collection.
    Science, 2002. 296(5565): p. 141-5
    [PMID:11910074]
  3. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  4. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  5. Froehlich JE, et al.
    Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.
    J. Proteome Res., 2003 Jul-Aug. 2(4): p. 413-25
    [PMID:12938931]
  6. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  7. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  8. Gong W, et al.
    The development of protein microarrays and their applications in DNA-protein and protein-protein interaction analyses of Arabidopsis transcription factors.
    Mol Plant, 2008. 1(1): p. 27-41
    [PMID:19802365]
  9. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  10. Ahmad A, et al.
    bHLH106 Integrates Functions of Multiple Genes through Their G-Box to Confer Salt Tolerance on Arabidopsis.
    PLoS ONE, 2015. 10(5): p. e0126872
    [PMID:25978450]
  11. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]