PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT2G40350.1
Common NameDREB2H, ERF047, T3G21.12
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family ERF
Protein Properties Length: 157aa    MW: 17791.6 Da    PI: 10.6001
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT2G40350.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP2513.5e-1665115155
          AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 
                  ++y+GVr++  +g+WvAeIr+p   g r ++ +lg+f + +eAa a+++a k+++g
  AT2G40350.1  65 CDYTGVRQRT-WGKWVAEIREP---G-RgAKLWLGTFSSSYEAALAYDEASKAIYG 115
                  68*****999.**********8...4.45*********************999887 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF008476.5E-1265115IPR001471AP2/ERF domain
CDDcd000183.56E-2665123No hitNo description
PROSITE profilePS5103219.38866123IPR001471AP2/ERF domain
SMARTSM003801.5E-2966129IPR001471AP2/ERF domain
SuperFamilySSF541712.88E-1867124IPR016177DNA-binding domain
PRINTSPR003676.9E-86778IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.4E-2667123IPR001471AP2/ERF domain
PRINTSPR003676.9E-889105IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0010286Biological Processheat acclimation
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 157 aa     Download sequence    Send to blast
MPRKRKSRGT RDVAEILRKW REYNEQTEAD SCIDGGGSKP IRKAPPKRSR KGCMKGKGGP  60
ENGICDYTGV RQRTWGKWVA EIREPGRGAK LWLGTFSSSY EAALAYDEAS KAIYGQSARL  120
NLPLLPLCQA RLLHFLMNLK FVHVRIQMQD LVLVRSD
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gcc_A8e-1667124361ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
2gcc_A9e-1667124664ATERF1
3gcc_A9e-1667124664ATERF1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.506730.0flower
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO795721060.0
Genevisible263823_s_at0.0
Expression AtlasAT2G40350-
AtGenExpressAT2G40350-
Functional Description ? help Back to Top
Source Description
TAIRencodes a member of the DREB subfamily A-2 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are eight members in this subfamily including DREB2A AND DREB2B that are involved in response to drought.
UniProtPutative transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. {ECO:0000250, ECO:0000269|PubMed:11798174}.
Function -- GeneRIF ? help Back to Top
  1. A trans activator involved in cold acclimatization.
    [PMID: 15341633]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT2G40350.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT2G40350
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC0070200.0AC007020.5 Arabidopsis thaliana chromosome 2 clone T3G21 map g4514, complete sequence.
GenBankCP0026850.0CP002685.1 Arabidopsis thaliana chromosome 2, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_181566.21e-114Integrase-type DNA-binding superfamily protein
SwissprotQ9SIZ01e-115DRE2H_ARATH; Putative dehydration-responsive element-binding protein 2H
TrEMBLA0A1P8B1T11e-111A0A1P8B1T1_ARATH; Integrase-type DNA-binding superfamily protein
STRINGAT2G40350.11e-113(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM85322538
Representative plantOGRP6161718
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Sakuma Y, et al.
    DNA-binding specificity of the ERF/AP2 domain of Arabidopsis DREBs, transcription factors involved in dehydration- and cold-inducible gene expression.
    Biochem. Biophys. Res. Commun., 2002. 290(3): p. 998-1009
    [PMID:11798174]
  3. Rizhsky L, et al.
    When defense pathways collide. The response of Arabidopsis to a combination of drought and heat stress.
    Plant Physiol., 2004. 134(4): p. 1683-96
    [PMID:15047901]
  4. Zhang X, et al.
    Freezing-sensitive tomato has a functional CBF cold response pathway, but a CBF regulon that differs from that of freezing-tolerant Arabidopsis.
    Plant J., 2004. 39(6): p. 905-19
    [PMID:15341633]
  5. Vanderauwera S, et al.
    Genome-wide analysis of hydrogen peroxide-regulated gene expression in Arabidopsis reveals a high light-induced transcriptional cluster involved in anthocyanin biosynthesis.
    Plant Physiol., 2005. 139(2): p. 806-21
    [PMID:16183842]
  6. Lee BH,Henderson DA,Zhu JK
    The Arabidopsis cold-responsive transcriptome and its regulation by ICE1.
    Plant Cell, 2005. 17(11): p. 3155-75
    [PMID:16214899]
  7. Nakano T,Suzuki K,Fujimura T,Shinshi H
    Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
    Plant Physiol., 2006. 140(2): p. 411-32
    [PMID:16407444]
  8. Lim CJ, et al.
    Gene expression profiles during heat acclimation in Arabidopsis thaliana suspension-culture cells.
    J. Plant Res., 2006. 119(4): p. 373-83
    [PMID:16807682]
  9. Zhang X,Wollenweber B,Jiang D,Liu F,Zhao J
    Water deficits and heat shock effects on photosynthesis of a transgenic Arabidopsis thaliana constitutively expressing ABP9, a bZIP transcription factor.
    J. Exp. Bot., 2008. 59(4): p. 839-48
    [PMID:18272919]
  10. Welling A,Palva ET
    Involvement of CBF transcription factors in winter hardiness in birch.
    Plant Physiol., 2008. 147(3): p. 1199-211
    [PMID:18467468]
  11. Yang TJ,Perry PJ,Ciani S,Pandian S,Schmidt W
    Manganese deficiency alters the patterning and development of root hairs in Arabidopsis.
    J. Exp. Bot., 2008. 59(12): p. 3453-64
    [PMID:18772308]
  12. Huang Y,Li CY,Biddle KD,Gibson SI
    Identification, cloning and characterization of sis7 and sis10 sugar-insensitive mutants of Arabidopsis.
    BMC Plant Biol., 2008. 8: p. 104
    [PMID:18854047]
  13. Efroni I, et al.
    Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses.
    Dev. Cell, 2013. 24(4): p. 438-45
    [PMID:23449474]