PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT2G36450.1
Common NameERF024, F1O11.8, HRD
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family ERF
Protein Properties Length: 184aa    MW: 19790.2 Da    PI: 4.5553
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT2G36450.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP259.39.4e-191464255
          AP2  2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55
                  y+GVr++k++++Wv+eIr+p+    +  r++lg+f t+e+Aa a++ a+++l+g
  AT2G36450.1 14 LYRGVRQRKNSNKWVSEIREPR----KpNRIWLGTFSTPEMAAIAYDVAALALKG 64
                 69******************94....478***********************987 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF008472.3E-121364IPR001471AP2/ERF domain
CDDcd000182.50E-291374No hitNo description
Gene3DG3DSA:3.30.730.101.6E-281473IPR001471AP2/ERF domain
SMARTSM003802.0E-321478IPR001471AP2/ERF domain
PROSITE profilePS5103221.4431472IPR001471AP2/ERF domain
SuperFamilySSF541711.77E-201474IPR016177DNA-binding domain
PRINTSPR003672.5E-81526IPR001471AP2/ERF domain
PRINTSPR003672.5E-85474IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009873Biological Processethylene-activated signaling pathway
GO:0050832Biological Processdefense response to fungus
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0009010anatomyseed
PO:0009032anatomypetal
PO:0020122anatomyinflorescence axis
PO:0001016developmental stageL mature pollen stage
Sequence ? help Back to Top
Protein Sequence    Length: 184 aa     Download sequence    Send to blast
MQGTSKDNGG RHPLYRGVRQ RKNSNKWVSE IREPRKPNRI WLGTFSTPEM AAIAYDVAAL  60
ALKGSQAELN FPNSVSSLPA PTSMSPADIQ AAAASAAAAF GAARDAIVMA NNNSQTSGVA  120
CMNSSYDNTN MNGFMDEDLV FDMPNVLMNM AEGMLLSPPR PTVFDAAYDA DGFPGGDDYL  180
WNFP
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2gcc_A1e-141077368ATERF1
3gcc_A1e-141077368ATERF1
Search in ModeBase
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO184041370.0
Genevisible263917_at0.0
Expression AtlasAT2G36450-
AtGenExpressAT2G36450-
ATTED-IIAT2G36450-
Functional Description ? help Back to Top
Source Description
TAIRencodes a member of the DREB subfamily A-4 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 17 members in this subfamily including TINY. Ectopic overexpression of HRD increases the density of the root network and improves water and salt stress tolerance in Arabidopsis. Overexpression of HRD in rice causes an increase in plant biomass and drought resistance.
UniProtProbably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.
Function -- GeneRIF ? help Back to Top
  1. HARDY is an Arabidopsis drought and salt tolerance gene [HARDY]
    [PMID: 17881564]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT2G36450.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT2G36450
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC0069190.0AC006919.6 Arabidopsis thaliana chromosome 2 clone F1O11 map g6825, complete sequence.
GenBankAY5608670.0AY560867.1 Arabidopsis thaliana putative AP2/EREBP transcription factor (At2g36450) mRNA, complete cds.
GenBankCP0026850.0CP002685.1 Arabidopsis thaliana chromosome 2, complete sequence.
GenBankDQ4466040.0DQ446604.1 Arabidopsis thaliana clone pENTR221-At2g36450 AP2 domain-containing protein (At2g36450) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_181186.11e-134Integrase-type DNA-binding superfamily protein
SwissprotQ9SJR01e-135ERF24_ARATH; Ethylene-responsive transcription factor ERF024
TrEMBLA0A178VW601e-131A0A178VW60_ARATH; HRD
STRINGAT2G36450.11e-133(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM64242546
Representative plantOGRP6161718
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Nakano T,Suzuki K,Fujimura T,Shinshi H
    Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
    Plant Physiol., 2006. 140(2): p. 411-32
    [PMID:16407444]
  3. Underwood BA,Vanderhaeghen R,Whitford R,Town CD,Hilson P
    Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.
    Plant Biotechnol. J., 2006. 4(3): p. 317-24
    [PMID:17147637]
  4. Karaba A, et al.
    Improvement of water use efficiency in rice by expression of HARDY, an Arabidopsis drought and salt tolerance gene.
    Proc. Natl. Acad. Sci. U.S.A., 2007. 104(39): p. 15270-5
    [PMID:17881564]
  5. Huibers RP,de Jong M,Dekter RW,Van den Ackerveken G
    Disease-specific expression of host genes during downy mildew infection of Arabidopsis.
    Mol. Plant Microbe Interact., 2009. 22(9): p. 1104-15
    [PMID:19656045]
  6. Abogadallah GM,Nada RM,Malinowski R,Quick P
    Overexpression of HARDY, an AP2/ERF gene from Arabidopsis, improves drought and salt tolerance by reducing transpiration and sodium uptake in transgenic Trifolium alexandrinum L.
    Planta, 2011. 233(6): p. 1265-76
    [PMID:21340699]
  7. Blanvillain R,Wei S,Wei P,Kim JH,Ow DW
    Stress tolerance to stress escape in plants: role of the OXS2 zinc-finger transcription factor family.
    EMBO J., 2011. 30(18): p. 3812-22
    [PMID:21829164]
  8. Shanker AK, et al.
    In silico targeted genome mining and comparative modelling reveals a putative protein similar to an Arabidopsis drought tolerance DNA binding transcription factor in Chromosome 6 of Sorghum bicolor genome.
    Interdiscip Sci, 2012. 4(2): p. 133-41
    [PMID:22843236]
  9. Efroni I, et al.
    Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses.
    Dev. Cell, 2013. 24(4): p. 438-45
    [PMID:23449474]