PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT2G35530.1
Common NameAtbZIP16, bZIP16
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bZIP
Protein Properties Length: 409aa    MW: 43109.3 Da    PI: 5.2796
Description basic region/leucine zipper transcription factor 16
Gene Model
Gene Model ID Type Source Coding Sequence
AT2G35530.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1bZIP_1729e-23303365163
                  XXXXCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
       bZIP_1   1 ekelkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkevaklksev 63 
                  ++elkr+rrkq+NRe+ArrsR+RK+ae++eL++++++L +eN+ L+ e+++lk ++++l++e+
  AT2G35530.1 303 DRELKRQRRKQSNRESARRSRLRKQAECDELAQRAEVLNEENTNLRAEINKLKSQCEELTTEN 365
                  689*********************************************************998 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF077772.5E-281103IPR012900G-box binding protein, multifunctional mosaic region
PfamPF165962.5E-46142272No hitNo description
Gene3DG3DSA:1.20.5.1701.2E-17296362No hitNo description
SMARTSM003381.8E-20303367IPR004827Basic-leucine zipper domain
PfamPF001701.8E-20304365IPR004827Basic-leucine zipper domain
PROSITE profilePS5021713.173305368IPR004827Basic-leucine zipper domain
SuperFamilySSF579591.5E-10306362No hitNo description
CDDcd147021.88E-24308358No hitNo description
PROSITE patternPS000360310325IPR004827Basic-leucine zipper domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 409 aa     Download sequence    Send to blast
MASNEMEKSS KEKEPKTPPP SSTAPPSSQE PSSAVSAGMA TPDWSGFQAY SPMPPPHGYV  60
ASSPQPHPYM WGVQHMMPPY GTPPHPYVAM YPPGGMYAHP SMPPGSYPYS PYAMPSPNGM  120
TEVSGNTTGG TDGDAKQSEV KEKLPIKRSR GSLGSLNMIT GKNNEPGKNS GASANGAYSK  180
SGESASDGSS EGSDGNSQND SGSGLDGKDA EAASENGGSA NGPQNGSAGT PILPVSQTVP  240
IMPMTAAGVP GPPTNLNIGM DYWGAPTSAG IPGMHGKVST PVPGVVAPGS RDGGHSQPWL  300
QDDRELKRQR RKQSNRESAR RSRLRKQAEC DELAQRAEVL NEENTNLRAE INKLKSQCEE  360
LTTENTSLKD QLSLFPPLEG ISMDNDHQEP DTNQTGAAER KVDSYKDST
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1319325RRSRLRK
2319326RRSRLRKQ
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.376630.0seed| silique
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO1453616580.0
Genevisible266634_at0.0
Expression AtlasAT2G35530-
AtGenExpressAT2G35530-
ATTED-IIAT2G35530-
Functional Description ? help Back to Top
Source Description
TAIREncodes a G group bZIP transcription factor family member that can bind cis elements with an ACGT core, such as G-box, Hex, C-box and As-1. The protein is localized in the nucleus and can homodimerize and can heterodimerize with other G group members.
UniProtTranscriptional activator that binds to the G-box motif (5'-CACGTG-3') and other cis-acting elements with 5'-ACGT-3' core, such as Hex, C-box and as-1 motifs. Possesses high binding affinity to G-box, much lower affinity to Hex and C-box, and little affinity to as-1 element (PubMed:18315949). G-box and G-box-like motifs are cis-acting elements defined in promoters of certain plant genes which are regulated by such diverse stimuli as light-induction or hormone control (Probable). Binds to the G-box motif 5'-CACGTG-3' of LHCB2.4 (At3g27690) promoter. May act as transcriptional repressor in light-regulated expression of LHCB2.4. Binds DNA as monomer. DNA-binding activity is redox-dependent (PubMed:22718771). {ECO:0000269|PubMed:18315949, ECO:0000269|PubMed:22718771, ECO:0000305|PubMed:18315949}.
Function -- GeneRIF ? help Back to Top
  1. bZIP16 functions to promote seed germination and hypocotyl elongation during the early stages of Arabidopsis seedling development.
    [PMID: 23104829]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00291DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT2G35530.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Interaction ? help Back to Top
Source Intact With
BioGRIDAT4G36730, AT1G32150
IntActSearch Q501B2
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT2G35530
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0264410.0BT026441.1 Arabidopsis thaliana At2g35530 mRNA, complete cds.
GenBankBT0220550.0BT022055.1 Arabidopsis thaliana At2g35530 gene, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_850248.20.0basic region/leucine zipper transcription factor 16
SwissprotQ501B20.0BZP16_ARATH; bZIP transcription factor 16
TrEMBLD7LHX20.0D7LHX2_ARALL; Putative uncharacterized protein
STRINGAT2G35530.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP7001767
MalvidsOGEM37012557
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Jakoby M, et al.
    bZIP transcription factors in Arabidopsis.
    Trends Plant Sci., 2002. 7(3): p. 106-11
    [PMID:11906833]
  3. Dal Bosco C, et al.
    Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana.
    J. Biol. Chem., 2004. 279(2): p. 1060-9
    [PMID:14576160]
  4. Satoh R,Fujita Y,Nakashima K,Shinozaki K,Yamaguchi-Shinozaki K
    A novel subgroup of bZIP proteins functions as transcriptional activators in hypoosmolarity-responsive expression of the ProDH gene in Arabidopsis.
    Plant Cell Physiol., 2004. 45(3): p. 309-17
    [PMID:15047879]
  5. Deppmann CD, et al.
    Dimerization specificity of all 67 B-ZIP motifs in Arabidopsis thaliana: a comparison to Homo sapiens B-ZIP motifs.
    Nucleic Acids Res., 2004. 32(11): p. 3435-45
    [PMID:15226410]
  6. Deppmann CD,Alvania RS,Taparowsky EJ
    Cross-species annotation of basic leucine zipper factor interactions: Insight into the evolution of closed interaction networks.
    Mol. Biol. Evol., 2006. 23(8): p. 1480-92
    [PMID:16731568]
  7. Shen H,Cao K,Wang X
    AtbZIP16 and AtbZIP68, two new members of GBFs, can interact with other G group bZIPs in Arabidopsis thaliana.
    BMB Rep, 2008. 41(2): p. 132-8
    [PMID:18315949]
  8. Reiland S, et al.
    Large-scale Arabidopsis phosphoproteome profiling reveals novel chloroplast kinase substrates and phosphorylation networks.
    Plant Physiol., 2009. 150(2): p. 889-903
    [PMID:19376835]
  9. Shaikhali J, et al.
    Redox-mediated mechanisms regulate DNA binding activity of the G-group of basic region leucine zipper (bZIP) transcription factors in Arabidopsis.
    J. Biol. Chem., 2012. 287(33): p. 27510-25
    [PMID:22718771]
  10. Hsieh WP,Hsieh HL,Wu SH
    Arabidopsis bZIP16 transcription factor integrates light and hormone signaling pathways to regulate early seedling development.
    Plant Cell, 2012. 24(10): p. 3997-4011
    [PMID:23104829]
  11. Shaikhali J
    GIP1 protein is a novel cofactor that regulates DNA-binding affinity of redox-regulated members of bZIP transcription factors involved in the early stages of Arabidopsis development.
    Protoplasma, 2015. 252(3): p. 867-83
    [PMID:25387999]