PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT2G33550.1
Common NameASR3, F4P9.32
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family Trihelix
Protein Properties Length: 314aa    MW: 34861.3 Da    PI: 6.0421
Description Trihelix family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT2G33550.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1trihelix933.1e-2938131185
     trihelix   1 rWtkqevlaLiearremeerlrrgk.........lkkplWeevskkmrergferspkqCkekwenlnkrykkikegekkrtsessstcpyfdql 85 
                  rWt+qe+l+Li+++r  e+r+rrg+         +++p+W++vs++++++g++r+p+qC+++w+nl+++ykkike+e++ ++e++s +++ +++
  AT2G33550.1  38 RWTRQEILVLIQGKRVAENRVRRGRaagmalgsgQMEPKWASVSSYCKRHGVNRGPVQCRKRWSNLAGDYKKIKEWESQIKEETESYWVMRNDV 131
                  8**********************97778888888******************************************************999886 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.605.3E-538103IPR009057Homeodomain-like
PfamPF138377.4E-1338127No hitNo description
PROSITE profilePS500906.438104IPR017877Myb-like domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006952Biological Processdefense response
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0050777Biological Processnegative regulation of immune response
GO:0071219Biological Processcellular response to molecule of bacterial origin
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0042803Molecular Functionprotein homodimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000293anatomyguard cell
Sequence ? help Back to Top
Protein Sequence    Length: 314 aa     Download sequence    Send to blast
MALEQLGLGV SAVDGGENSS APSNDGGDDG VKTARLPRWT RQEILVLIQG KRVAENRVRR  60
GRAAGMALGS GQMEPKWASV SSYCKRHGVN RGPVQCRKRW SNLAGDYKKI KEWESQIKEE  120
TESYWVMRND VRREKKLPGF FDKEVYDIVD GGVIPPAVPV LSLGLAPASD EGLLSDLDRR  180
ESPEKLNSTP VAKSVTDVID KEKQEACVAD QGRVKEKQPE AANVEGGSTS QEERKRKRTS  240
FGEKEEEEEE GETKKMQNQL IEILERNGQL LAAQLEVQNL NLKLDREQRK DHGDSLVAVL  300
NKLADAVAKI ADKM
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.285160.0root
Expression -- Microarray ? help Back to Top
Source ID
Expression AtlasAT2G33550
AtGenExpressAT2G33550
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional repressor that binds DNA and plays a negative role in regulating microbe-associated molecular patterns-(MAMPs, e.g. flg22, elf18, chitin, and LPS) triggered immunity (PTI) by negatively regulating immune gene expression. {ECO:0000269|PubMed:25770109}.
Function -- GeneRIF ? help Back to Top
  1. ASR3 functions as a transcriptional repressor regulated by microbe-associated molecular patterns-activated MPK4 to fine-tune plant immune gene expression.
    [PMID: 25770109]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00288DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT2G33550.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Interaction ? help Back to Top
Source Intact With
IntActSearch Q8VZ20
Phenotype -- Disruption Phenotype ? help Back to Top
Source Description
UniProtDISRUPTION PHENOTYPE: Enhanced disease resistance to virulent bacterial pathogen infection such as P. syringae pv tomato (Pst) DC3000 and P. syringae pv maculicola (Psm) ES4326 associated with immune gene activation. {ECO:0000269|PubMed:25770109}.
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT2G33550
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY0963890.0AY096389.1 Arabidopsis thaliana unknown protein (At2g33550) mRNA, complete cds.
GenBankAY0653640.0AY065364.1 Arabidopsis thaliana unknown protein (At2g33550) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_850213.10.0Myb/SANT-like DNA-binding domain-containing protein
SwissprotQ8VZ200.0ASR3_ARATH; Trihelix transcription factor ASR3
TrEMBLD7LGB50.0D7LGB5_ARALL; Putative uncharacterized protein
STRINGAT2G33550.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP17471336
MalvidsOGEM65572843
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  3. Scheible WR, et al.
    Genome-wide reprogramming of primary and secondary metabolism, protein synthesis, cellular growth processes, and the regulatory infrastructure of Arabidopsis in response to nitrogen.
    Plant Physiol., 2004. 136(1): p. 2483-99
    [PMID:15375205]
  4. Jaspers P, et al.
    Unequally redundant RCD1 and SRO1 mediate stress and developmental responses and interact with transcription factors.
    Plant J., 2009. 60(2): p. 268-79
    [PMID:19548978]
  5. Castrillo G, et al.
    Speeding cis-trans regulation discovery by phylogenomic analyses coupled with screenings of an arrayed library of Arabidopsis transcription factors.
    PLoS ONE, 2011. 6(6): p. e21524
    [PMID:21738689]
  6. Arabidopsis Interactome Mapping Consortium
    Evidence for network evolution in an Arabidopsis interactome map.
    Science, 2011. 333(6042): p. 601-7
    [PMID:21798944]
  7. Causier B,Ashworth M,Guo W,Davies B
    The TOPLESS interactome: a framework for gene repression in Arabidopsis.
    Plant Physiol., 2012. 158(1): p. 423-38
    [PMID:22065421]
  8. Li B, et al.
    Phosphorylation of trihelix transcriptional repressor ASR3 by MAP KINASE4 negatively regulates Arabidopsis immunity.
    Plant Cell, 2015. 27(3): p. 839-56
    [PMID:25770109]