PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT2G31070.1
Common NameT16B12.12, TCP10
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family TCP
Protein Properties Length: 361aa    MW: 40379.2 Da    PI: 7.1217
Description TCP domain protein 10
Gene Model
Gene Model ID Type Source Coding Sequence
AT2G31070.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1TCP109.93.8e-3426119182
          TCP   1 aagkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgt............ssssaseceaesssssa 82 
                  a+g+kdrhsk+ T++g+RdRRvRlsa++a++f+d+qd+LG+d++sk+++WL+++ak+ai++l               +++++s +   ++++++
  AT2G31070.1  26 ATGRKDRHSKVFTSKGPRDRRVRLSAHTAIQFYDVQDRLGYDRPSKAVDWLIKKAKTAIDKLELGettttttrqepvNTKPESPTLVFQRENND 119
                  589**********************************************************987744544444444433333333222222222 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF036344.6E-3227120IPR005333Transcription factor, TCP
PROSITE profilePS5136932.2972987IPR017887Transcription factor TCP subgroup
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009965Biological Processleaf morphogenesis
GO:0030154Biological Processcell differentiation
GO:0045962Biological Processpositive regulation of development, heterochronic
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000056anatomyflower bud
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009001anatomyfruit
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 361 aa     Download sequence    Send to blast
MGLKGYSVGE GGGEIVEVQG GHIIRATGRK DRHSKVFTSK GPRDRRVRLS AHTAIQFYDV  60
QDRLGYDRPS KAVDWLIKKA KTAIDKLELG ETTTTTTRQE PVNTKPESPT LVFQRENNDQ  120
TQFVAANLDP EDAMKTFFPA TTTTNGGGGT NINFQNYPHQ DDNNMVSRTT TPPPNLSQDL  180
GLSLHPFQGN NNTVVVPETN NFTTTHFDTF GRISGWNHHD LTMTSSSSSE HQQQEQEERS  240
NGGFMVNHHP HHHHHQPSMM TLLNSQQQQV FLGGQQQQQQ RGTLQSSLFP HSFRSWDHHQ  300
TTSDHHHHQN QASSMFASSS QYGSHGMMMM QGLSFPNTTR LLHGEEATQP NSSSSPPNSH  360
L
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5zkt_A5e-223487154Putative transcription factor PCF6
5zkt_B5e-223487154Putative transcription factor PCF6
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.252380.0bud| leaf
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO306848060.0
Genevisible266481_at0.0
Expression AtlasAT2G31070-
AtGenExpressAT2G31070-
ATTED-IIAT2G31070-
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: First observed in the distal and middle regions of cotyledons of heart-shaped embryos. Later localized in bending cotyledon, and mature embryos, but no signals were detected in the presumptive shoot apical meristem (SAM) and the boundary region during embryogenesis. Expressed during ovule development (PubMed:25378179). {ECO:0000269|PubMed:17307931, ECO:0000269|PubMed:25378179}.
UniprotTISSUE SPECIFICITY: Mostly detected in lateral organs, such as leaves and flowers. Expressed in cotyledons, particularly in the vascular region, in leaves, roots, stems, buds, flowers and immature siliques. {ECO:0000269|PubMed:11158442, ECO:0000269|PubMed:17307931}.
Functional Description ? help Back to Top
Source Description
TAIRTCP family protein involved in heterchronic regulation of leaf differentiation.
UniProtPlays a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes, probably through the induction of miRNA (e.g. miR164). Participates in ovule develpment (PubMed:25378179). {ECO:0000269|PubMed:17307931, ECO:0000269|PubMed:25378179}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT2G31070.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Interaction ? help Back to Top
Source Intact With
BioGRIDAT2G37000, AT3G15030, AT3G02150, AT3G27010, AT3G47620, AT4G18390, AT4G27330, AT5G08070, AT5G08330, AT5G51910, AT5G60970, AT1G14920, AT1G30210, AT1G35560, AT1G53230, AT1G58100, AT1G65620, AT1G69690
IntActSearch O82277
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT2G31070
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC0053110.0AC005311.3 Arabidopsis thaliana chromosome 2 clone T16B12 map m283, complete sequence.
GenBankAY0599450.0AY059945.1 Arabidopsis thaliana Unknown protein (At2g31070; T16B12.12) mRNA, complete cds.
GenBankBT0011940.0BT001194.1 Arabidopsis thaliana Unknown protein (At2g31070) mRNA, complete cds.
GenBankCP0026850.0CP002685.1 Arabidopsis thaliana chromosome 2, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_565712.10.0TCP domain protein 10
SwissprotO822770.0TCP10_ARATH; Transcription factor TCP10
TrEMBLD7LCY30.0D7LCY3_ARALL; Uncharacterized protein
STRINGAT2G31070.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM141581924
Representative plantOGRP18015163
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Suzuki T,Sakurai K,Ueguchi C,Mizuno T
    Two types of putative nuclear factors that physically interact with histidine-containing phosphotransfer (Hpt) domains, signaling mediators in His-to-Asp phosphorelay, in Arabidopsis thaliana.
    Plant Cell Physiol., 2001. 42(1): p. 37-45
    [PMID:11158442]
  3. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  4. Qin G, et al.
    An indole-3-acetic acid carboxyl methyltransferase regulates Arabidopsis leaf development.
    Plant Cell, 2005. 17(10): p. 2693-704
    [PMID:16169896]
  5. Damerval C,Le Guilloux M,Jager M,Charon C
    Diversity and evolution of CYCLOIDEA-like TCP genes in relation to flower development in Papaveraceae.
    Plant Physiol., 2007. 143(2): p. 759-72
    [PMID:17189327]
  6. Aguilar-Martínez JA,Poza-Carrión C,Cubas P
    Arabidopsis BRANCHED1 acts as an integrator of branching signals within axillary buds.
    Plant Cell, 2007. 19(2): p. 458-72
    [PMID:17307924]
  7. Koyama T,Furutani M,Tasaka M,Ohme-Takagi M
    TCP transcription factors control the morphology of shoot lateral organs via negative regulation of the expression of boundary-specific genes in Arabidopsis.
    Plant Cell, 2007. 19(2): p. 473-84
    [PMID:17307931]
  8. Efroni I,Blum E,Goldshmidt A,Eshed Y
    A protracted and dynamic maturation schedule underlies Arabidopsis leaf development.
    Plant Cell, 2008. 20(9): p. 2293-306
    [PMID:18805992]
  9. Nag A,King S,Jack T
    miR319a targeting of TCP4 is critical for petal growth and development in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2009. 106(52): p. 22534-9
    [PMID:20007771]
  10. Koyama T,Mitsuda N,Seki M,Shinozaki K,Ohme-Takagi M
    TCP transcription factors regulate the activities of ASYMMETRIC LEAVES1 and miR164, as well as the auxin response, during differentiation of leaves in Arabidopsis.
    Plant Cell, 2010. 22(11): p. 3574-88
    [PMID:21119060]
  11. Brady SM, et al.
    A stele-enriched gene regulatory network in the Arabidopsis root.
    Mol. Syst. Biol., 2011. 7: p. 459
    [PMID:21245844]
  12. Li Z,Li B,Shen WH,Huang H,Dong A
    TCP transcription factors interact with AS2 in the repression of class-I KNOX genes in Arabidopsis thaliana.
    Plant J., 2012. 71(1): p. 99-107
    [PMID:22380849]
  13. Danisman S, et al.
    Analysis of functional redundancies within the Arabidopsis TCP transcription factor family.
    J. Exp. Bot., 2013. 64(18): p. 5673-85
    [PMID:24129704]
  14. Mar
    Large-scale identification of gibberellin-related transcription factors defines group VII ETHYLENE RESPONSE FACTORS as functional DELLA partners.
    Plant Physiol., 2014. 166(2): p. 1022-32
    [PMID:25118255]
  15. Wei B, et al.
    The molecular mechanism of sporocyteless/nozzle in controlling Arabidopsis ovule development.
    Cell Res., 2015. 25(1): p. 121-34
    [PMID:25378179]
  16. Chen GH,Sun JY,Liu M,Liu J,Yang WC
    SPOROCYTELESS is a novel embryophyte-specific transcription repressor that interacts with TPL and TCP proteins in Arabidopsis.
    J Genet Genomics, 2014. 41(12): p. 617-25
    [PMID:25527103]
  17. Koyama T,Sato F,Ohme-Takagi M
    Roles of miR319 and TCP Transcription Factors in Leaf Development.
    Plant Physiol., 2017. 175(2): p. 874-885
    [PMID:28842549]
  18. Bresso EG,Chorostecki U,Rodriguez RE,Palatnik JF,Schommer C
    Spatial Control of Gene Expression by miR319-Regulated TCP Transcription Factors in Leaf Development.
    Plant Physiol., 2018. 176(2): p. 1694-1708
    [PMID:29133375]