PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT2G30590.1
Common NameT06B20.6, T6B20.6, WRKY21
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family WRKY
Protein Properties Length: 380aa    MW: 43005.4 Da    PI: 10.3139
Description WRKY DNA-binding protein 21
Gene Model
Gene Model ID Type Source Coding Sequence
AT2G30590.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY98.15.9e-31314372360
                  -SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS-- CS
         WRKY   3 DgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhek 60 
                  D y+WrKYGqK++kgs++pr+YY+C+s  gCp++k+ver+ edp ++++tYe eHnh+k
  AT2G30590.1 314 DDYSWRKYGQKPIKGSPYPRGYYKCSSMrGCPARKHVERCLEDPAMLIVTYEAEHNHPK 372
                  99***********************9988****************************85 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF105336.0E-17264310IPR018872Zn-cluster domain
Gene3DG3DSA:2.20.25.804.0E-33300372IPR003657WRKY domain
PROSITE profilePS5081130.366307373IPR003657WRKY domain
SuperFamilySSF1182901.31E-26310372IPR003657WRKY domain
SMARTSM007742.0E-37312372IPR003657WRKY domain
PfamPF031062.0E-26314371IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005516Molecular Functioncalmodulin binding
GO:0043565Molecular Functionsequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 380 aa     Download sequence    Send to blast
MEEIEGTNRA AVESCHRVLN LLHRSQQQDH VGFEKNLVSE TREAVIRFKR VGSLLSSSVG  60
HARFRRAKKL QSHVSQSLLL DPCQQRTTEV PSSSSQKTPV LRSGFQELSL RQPSDSLTLG  120
TRSFSLNSNA KAPLLQLNQQ TMPPSNYPTL FPVQQQQQQQ QQQQQQEQQQ QQQQQQQQFH  180
ERLQAHHLHQ QQQLQKHQAE LMLRKCNGGI SLSFDNSSCT PTMSSTRSFV SSLSIDGSVA  240
NIEGKNSFHF GVPSSTDQNS LHSKRKCPLK GDEHGSLKCG SSSRCHCAKK RKHRVRRSIR  300
VPAISNKVAD IPPDDYSWRK YGQKPIKGSP YPRGYYKCSS MRGCPARKHV ERCLEDPAML  360
IVTYEAEHNH PKLPSQAITT
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ayd_A1e-20300375276WRKY transcription factor 1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.147270.0bud| flower| leaf| vegetative tissue
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO306846480.0
Genevisible267469_at0.0
Expression AtlasAT2G30590-
AtGenExpressAT2G30590-
ATTED-IIAT2G30590-
Functional Description ? help Back to Top
Source Description
TAIREncodes WRKY DNA-binding protein 21 (WRKY21).
UniProtTranscription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00284DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT2G30590.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By salicylic acid. {ECO:0000269|PubMed:11449049}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Interaction ? help Back to Top
Source Intact With
BioGRIDAT3G24140, AT4G08150
IntActSearch O04336
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT2G30590
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF2727470.0AF272747.1 Arabidopsis thaliana WRKY DNA-binding protein 21 (WRKY21) mRNA, complete cds.
GenBankAY1364410.0AY136441.1 Arabidopsis thaliana expressed protein (At2g30590) mRNA, complete cds.
GenBankBT0002310.0BT000231.1 Arabidopsis thaliana expressed protein (At2g30590) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_565703.10.0WRKY DNA-binding protein 21
SwissprotO043360.0WRK21_ARATH; Probable WRKY transcription factor 21
TrEMBLA0A178VWW80.0A0A178VWW8_ARATH; WRKY21
STRINGAT2G30590.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM35672861
Representative plantOGRP18171541
Publications ? help Back to Top
  1. Eulgem T,Rushton PJ,Robatzek S,Somssich IE
    The WRKY superfamily of plant transcription factors.
    Trends Plant Sci., 2000. 5(5): p. 199-206
    [PMID:10785665]
  2. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  3. Yu D,Chen C,Chen Z
    Evidence for an important role of WRKY DNA binding proteins in the regulation of NPR1 gene expression.
    Plant Cell, 2001. 13(7): p. 1527-40
    [PMID:11449049]
  4. Kreps JA, et al.
    Transcriptome changes for Arabidopsis in response to salt, osmotic, and cold stress.
    Plant Physiol., 2002. 130(4): p. 2129-41
    [PMID:12481097]
  5. Whitham SA, et al.
    Diverse RNA viruses elicit the expression of common sets of genes in susceptible Arabidopsis thaliana plants.
    Plant J., 2003. 33(2): p. 271-83
    [PMID:12535341]
  6. Vlieghe K, et al.
    Microarray analysis of E2Fa-DPa-overexpressing plants uncovers a cross-talking genetic network between DNA replication and nitrogen assimilation.
    J. Cell. Sci., 2003. 116(Pt 20): p. 4249-59
    [PMID:12953064]
  7. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  8. Park CY, et al.
    WRKY group IId transcription factors interact with calmodulin.
    FEBS Lett., 2005. 579(6): p. 1545-50
    [PMID:15733871]
  9. Phelps-Durr TL,Thomas J,Vahab P,Timmermans MC
    Maize rough sheath2 and its Arabidopsis orthologue ASYMMETRIC LEAVES1 interact with HIRA, a predicted histone chaperone, to maintain knox gene silencing and determinacy during organogenesis.
    Plant Cell, 2005. 17(11): p. 2886-98
    [PMID:16243907]
  10. Tosti N, et al.
    Gene expression profiles of O3-treated Arabidopsis plants.
    Plant Cell Environ., 2006. 29(9): p. 1686-702
    [PMID:16913859]
  11. Journot-Catalino N,Somssich IE,Roby D,Kroj T
    The transcription factors WRKY11 and WRKY17 act as negative regulators of basal resistance in Arabidopsis thaliana.
    Plant Cell, 2006. 18(11): p. 3289-302
    [PMID:17114354]
  12. Popescu SC, et al.
    Differential binding of calmodulin-related proteins to their targets revealed through high-density Arabidopsis protein microarrays.
    Proc. Natl. Acad. Sci. U.S.A., 2007. 104(11): p. 4730-5
    [PMID:17360592]
  13. Arabidopsis Interactome Mapping Consortium
    Evidence for network evolution in an Arabidopsis interactome map.
    Science, 2011. 333(6042): p. 601-7
    [PMID:21798944]