PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT2G23320.1
Common NameAtWRKY15, T20D16.5, WRKY15
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family WRKY
Protein Properties Length: 317aa    MW: 34263.6 Da    PI: 10.3009
Description WRKY DNA-binding protein 15
Gene Model
Gene Model ID Type Source Coding Sequence
AT2G23320.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY1001.5e-31241298359
                  -SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS
         WRKY   3 DgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 
                  D y+WrKYGqK++kgs++pr+YY+C+s  gCp++k+ver+a+d +++++tYeg+Hnh+
  AT2G23320.1 241 DDYSWRKYGQKPIKGSPHPRGYYKCSSVrGCPARKHVERAADDSSMLIVTYEGDHNHS 298
                  99************************988****************************7 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF105336.4E-16190237IPR018872Zn-cluster domain
Gene3DG3DSA:2.20.25.804.2E-33228298IPR003657WRKY domain
PROSITE profilePS5081130.607234300IPR003657WRKY domain
SuperFamilySSF1182908.76E-27237299IPR003657WRKY domain
SMARTSM007741.7E-37239299IPR003657WRKY domain
PfamPF031063.9E-27241297IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010200Biological Processresponse to chitin
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005516Molecular Functioncalmodulin binding
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000084anatomyplant sperm cell
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025195anatomypollen tube cell
PO:0025281anatomypollen
PO:0001016developmental stageL mature pollen stage
PO:0001017developmental stageM germinated pollen stage
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 317 aa     Download sequence    Send to blast
MAVELMTRNY ISGVGADSFA VQEAAASGLK SIENFIGLMS RDSFNSDQPS SSSASASASA  60
AADLESARNT TADAAVSKFK RVISLLDRTR TGHARFRRAP VHVISPVLLQ EEPKTTPFQS  120
PLPPPPQMIR KGSFSSSMKT IDFSSLSSVT TESDNQKKIH HHQRPSETAP FASQTQSLST  180
TVSSFSKSTK RKCNSENLLT GKCASASSSG RCHCSKKRKI KQRRIIRVPA ISAKMSDVPP  240
DDYSWRKYGQ KPIKGSPHPR GYYKCSSVRG CPARKHVERA ADDSSMLIVT YEGDHNHSLS  300
AADLAGAAVA DLILESS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ayd_A2e-22227299273WRKY transcription factor 1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.248830.0flower| leaf| root| seed| vegetative tissue
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO306820380.0
Genevisible245051_at0.0
Expression AtlasAT2G23320-
AtGenExpressAT2G23320-
ATTED-IIAT2G23320-
Functional Description ? help Back to Top
Source Description
TAIREncodes WRKY DNA-binding protein 15 (WRKY15).
UniProtTranscription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250}.
Function -- GeneRIF ? help Back to Top
  1. WRKY15 transcription factor modulates plant growth and salt/osmotic stress responses.
    [PMID: 23169634]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00275DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT2G23320.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By salicylic acid. {ECO:0000269|PubMed:11449049}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT2G23320
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF2247040.0AF224704.1 Arabidopsis thaliana WRKY DNA-binding protein 15 (WRKY15) mRNA, complete cds.
GenBankAY0629500.0AY062950.1 Arabidopsis thaliana putative WRKY-type DNA-binding protein (At2g23320) mRNA, complete cds.
GenBankAF3701940.0AF370194.1 Arabidopsis thaliana putative WRKY-type DNA-binding protein (At2g23320) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_179913.10.0WRKY DNA-binding protein 15
SwissprotO221760.0WRK15_ARATH; Probable WRKY transcription factor 15
TrEMBLR0HTZ80.0R0HTZ8_9BRAS; Uncharacterized protein
STRINGAT2G23320.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP1417875
MalvidsOGEM17152887
Publications ? help Back to Top
  1. Eulgem T,Rushton PJ,Robatzek S,Somssich IE
    The WRKY superfamily of plant transcription factors.
    Trends Plant Sci., 2000. 5(5): p. 199-206
    [PMID:10785665]
  2. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  3. Yu D,Chen C,Chen Z
    Evidence for an important role of WRKY DNA binding proteins in the regulation of NPR1 gene expression.
    Plant Cell, 2001. 13(7): p. 1527-40
    [PMID:11449049]
  4. Mahalingam R, et al.
    Characterizing the stress/defense transcriptome of Arabidopsis.
    Genome Biol., 2003. 4(3): p. R20
    [PMID:12620105]
  5. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  6. Navarro L, et al.
    The transcriptional innate immune response to flg22. Interplay and overlap with Avr gene-dependent defense responses and bacterial pathogenesis.
    Plant Physiol., 2004. 135(2): p. 1113-28
    [PMID:15181213]
  7. Guti
    Phylogenetic profiling of the Arabidopsis thaliana proteome: what proteins distinguish plants from other organisms?
    Genome Biol., 2004. 5(8): p. R53
    [PMID:15287975]
  8. Miao Y,Laun T,Zimmermann P,Zentgraf U
    Targets of the WRKY53 transcription factor and its role during leaf senescence in Arabidopsis.
    Plant Mol. Biol., 2004. 55(6): p. 853-67
    [PMID:15604721]
  9. Park CY, et al.
    WRKY group IId transcription factors interact with calmodulin.
    FEBS Lett., 2005. 579(6): p. 1545-50
    [PMID:15733871]
  10. Devoto A, et al.
    Expression profiling reveals COI1 to be a key regulator of genes involved in wound- and methyl jasmonate-induced secondary metabolism, defence, and hormone interactions.
    Plant Mol. Biol., 2005. 58(4): p. 497-513
    [PMID:16021335]
  11. Phelps-Durr TL,Thomas J,Vahab P,Timmermans MC
    Maize rough sheath2 and its Arabidopsis orthologue ASYMMETRIC LEAVES1 interact with HIRA, a predicted histone chaperone, to maintain knox gene silencing and determinacy during organogenesis.
    Plant Cell, 2005. 17(11): p. 2886-98
    [PMID:16243907]
  12. Tosti N, et al.
    Gene expression profiles of O3-treated Arabidopsis plants.
    Plant Cell Environ., 2006. 29(9): p. 1686-702
    [PMID:16913859]
  13. Cao D,Cheng H,Wu W,Soo HM,Peng J
    Gibberellin mobilizes distinct DELLA-dependent transcriptomes to regulate seed germination and floral development in Arabidopsis.
    Plant Physiol., 2006. 142(2): p. 509-25
    [PMID:16920880]
  14. AbuQamar S, et al.
    Expression profiling and mutant analysis reveals complex regulatory networks involved in Arabidopsis response to Botrytis infection.
    Plant J., 2006. 48(1): p. 28-44
    [PMID:16925600]
  15. Journot-Catalino N,Somssich IE,Roby D,Kroj T
    The transcription factors WRKY11 and WRKY17 act as negative regulators of basal resistance in Arabidopsis thaliana.
    Plant Cell, 2006. 18(11): p. 3289-302
    [PMID:17114354]
  16. Qutob D, et al.
    Phytotoxicity and innate immune responses induced by Nep1-like proteins.
    Plant Cell, 2006. 18(12): p. 3721-44
    [PMID:17194768]
  17. Libault M,Wan J,Czechowski T,Udvardi M,Stacey G
    Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-ligase genes responding to chitin, a plant-defense elicitor.
    Mol. Plant Microbe Interact., 2007. 20(8): p. 900-11
    [PMID:17722694]
  18. Ramel F, et al.
    Genome-wide interacting effects of sucrose and herbicide-mediated stress in Arabidopsis thaliana: novel insights into atrazine toxicity and sucrose-induced tolerance.
    BMC Genomics, 2007. 8: p. 450
    [PMID:18053238]
  19. Ho LH, et al.
    Identification of regulatory pathways controlling gene expression of stress-responsive mitochondrial proteins in Arabidopsis.
    Plant Physiol., 2008. 147(4): p. 1858-73
    [PMID:18567827]
  20. Ascencio-Ib
    Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.
    Plant Physiol., 2008. 148(1): p. 436-54
    [PMID:18650403]
  21. Wang Y, et al.
    Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.
    Plant Physiol., 2008. 148(3): p. 1201-11
    [PMID:18775970]
  22. Jakoby MJ, et al.
    Transcriptional profiling of mature Arabidopsis trichomes reveals that NOECK encodes the MIXTA-like transcriptional regulator MYB106.
    Plant Physiol., 2008. 148(3): p. 1583-602
    [PMID:18805951]
  23. Inz
    A subcellular localization compendium of hydrogen peroxide-induced proteins.
    Plant Cell Environ., 2012. 35(2): p. 308-20
    [PMID:21443605]
  24. Vanderauwera S, et al.
    AtWRKY15 perturbation abolishes the mitochondrial stress response that steers osmotic stress tolerance in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2012. 109(49): p. 20113-8
    [PMID:23169634]