PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT2G22760.1
Common NameBHLH19, EN26, T30L20.2
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 295aa    MW: 33787.1 Da    PI: 6.0821
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT2G22760.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH331.1e-10119165455
                  HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
          HLH   4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                   h  +Er+RR+++ ++f  L  llP +     kK +K++iL  A+  +k+Lq
  AT2G22760.1 119 EHVLAERKRREKLSEKFIALSALLPGL-----KKADKVTILDDAISRMKQLQ 165
                  5899***********************.....9******************9 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088814.615115164IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.4E-8119165IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.103.7E-16119181IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474596.28E-16119181IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.17E-10120169No hitNo description
SMARTSM003536.2E-14121170IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000005anatomycultured plant cell
PO:0000013anatomycauline leaf
PO:0000033anatomyfruit valve
PO:0000036anatomyleaf vascular system
PO:0000051anatomypetiole epidermis
PO:0000056anatomyflower bud
PO:0000112anatomyshoot axis epidermis
PO:0000293anatomyguard cell
PO:0004006anatomymesophyll cell
PO:0004707anatomyfruit dehiscence zone
PO:0006016anatomyleaf epidermis
PO:0006036anatomyroot epidermis
PO:0006040anatomysepal epidermis
PO:0006504anatomyleaf trichome
PO:0009005anatomyroot
PO:0009047anatomystem
PO:0009049anatomyinflorescence
PO:0009053anatomypeduncle
PO:0009081anatomyinflorescence branch
PO:0020127anatomyprimary root
PO:0020128anatomyleaf margin
Sequence ? help Back to Top
Protein Sequence    Length: 295 aa     Download sequence    Send to blast
MDEDFFLPDF SLVDIDFDFN IYEENNLSPD ESLSNSRRAD QSSKFDHQMH FECLREKPKA  60
AVKPMMKINN KQQLISFDFS SNVISSPAAE EIIMDKLVGR GTKRKTCSHG TRSPVLAKEH  120
VLAERKRREK LSEKFIALSA LLPGLKKADK VTILDDAISR MKQLQEQLRT LKEEKEATRQ  180
MESMILVKKS KVFFDEEPNL SCSPSVHIEF DQALPEIEAK ISQNDILIRI LCEKSKGCMI  240
NILNTIENFQ LRIENSIVLP FGDSTLDITV LAQMDKDFSM SILKDLVRNL RLAMV
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1123128ERKRRE
2124129RKRREK
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible266455_at0.0
Expression AtlasAT2G22760-
AtGenExpressAT2G22760-
ATTED-IIAT2G22760-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in roots and leaves. {ECO:0000269|PubMed:12679534}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT2G22760.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By cold treatment. {ECO:0000269|PubMed:12679534}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Interaction ? help Back to Top
Source Intact With
IntActSearch Q1PF16
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT2G22760
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankDQ4465500.0DQ446550.1 Arabidopsis thaliana clone pENTR221-At2g22760 basic helix-loop-helix family protein (At2g22760) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_179861.20.0transcription factor bHLH19
SwissprotQ1PF160.0BH019_ARATH; Transcription factor bHLH19
TrEMBLC0SV560.0C0SV56_ARATH; Putative uncharacterized protein At2g22760 (Fragment)
STRINGAT2G22760.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP6561573
MalvidsOGEM49227146
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  5. Matsushima R,Fukao Y,Nishimura M,Hara-Nishimura I
    NAI1 gene encodes a basic-helix-loop-helix-type putative transcription factor that regulates the formation of an endoplasmic reticulum-derived structure, the ER body.
    Plant Cell, 2004. 16(6): p. 1536-49
    [PMID:15155889]
  6. Ma S,Gong Q,Bohnert HJ
    Dissecting salt stress pathways.
    J. Exp. Bot., 2006. 57(5): p. 1097-107
    [PMID:16510518]
  7. Truman W,de Zabala MT,Grant M
    Type III effectors orchestrate a complex interplay between transcriptional networks to modify basal defence responses during pathogenesis and resistance.
    Plant J., 2006. 46(1): p. 14-33
    [PMID:16553893]
  8. Underwood BA,Vanderhaeghen R,Whitford R,Town CD,Hilson P
    Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.
    Plant Biotechnol. J., 2006. 4(3): p. 317-24
    [PMID:17147637]
  9. Colinas J,Schmidler SC,Bohrer G,Iordanov B,Benfey PN
    Intergenic and genic sequence lengths have opposite relationships with respect to gene expression.
    PLoS ONE, 2008. 3(11): p. e3670
    [PMID:18989364]
  10. Jaspers P, et al.
    Unequally redundant RCD1 and SRO1 mediate stress and developmental responses and interact with transcription factors.
    Plant J., 2009. 60(2): p. 268-79
    [PMID:19548978]
  11. Efroni I, et al.
    Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses.
    Dev. Cell, 2013. 24(4): p. 438-45
    [PMID:23449474]